Search Results - "Muenchmeier, Niklas"
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Nuclear transfer nTreg model reveals fate-determining TCR-β and novel peripheral nTreg precursors
Published in Proceedings of the National Academy of Sciences - PNAS (19-04-2016)“…To study the development and function of “natural-arising” T regulatory (nTreg) cells, we developed a novel nTreg model on pure nonobese diabetic background…”
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A novel CXCL10-based GPI-anchored fusion protein as adjuvant in NK-based tumor therapy
Published in PloS one (30-08-2013)“…Cellular therapy is a promising therapeutic strategy for malignant diseases. The efficacy of this therapy can be limited by poor infiltration of the tumor by…”
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Nuclear transfer nTreg model reveals fate-determining TCR-[Beta] and novel peripheral nTreg precursors
Published in Proceedings of the National Academy of Sciences - PNAS (19-04-2016)“…To study the development and function of "natural-arising" T regulatory (nTreg) cells, we developed a novel nTreg model on pure nonobese diabetic background…”
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Membrane-anchored chemokine fusion proteins: A novel class of adjuvants for immunotherapy
Published in Oncoimmunology (01-11-2013)“…Adoptive or active cancer immunotherapy can fail owing to the inefficient recruitment of effector leukocytes to malignant lesions. The intratumoral injection…”
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A multicenter retrospective evaluation of Chronic Myeloid Leukemia (CML) therapy in Austria assessing the impact of early treatment response on patient outcomes in a real-life setting: R-EFECT study
Published in Wiener Klinische Wochenschrift (01-08-2020)“…Summary Background Several clinical trials in chronic phase (CP) chronic myeloid leukemia (CML) showed that early response to tyrosine kinase inhibitor (TKI)…”
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Human Renal Cell Carcinoma Induces a Dendritic Cell Subset That Uses T-Cell Crosstalk for Tumor-Permissive Milieu Alterations
Published in The American journal of pathology (01-07-2011)“…Tissue dendritic cells (DCs) may influence the progression of renal cell carcinoma (RCC) by regulating the functional capacity of antitumor effector cells. DCs…”
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SDF‐1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization
Published in Stem cells (Dayton, Ohio) (01-09-2013)“…ABSTRACT The facilitated recruitment of vascular progenitor cells (VPCs) to ischemic areas might be a therapeutic target for neovascularization and repair…”
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A novel CXCL8 protein-based antagonist in acute experimental renal allograft damage
Published in Molecular immunology (01-02-2010)“…Acute renal allograft damage is caused by early leukocyte infiltration which is mediated in part by chemokines presented by glycosaminoglycan (GAG) structures…”
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Recruitment of Natural Killer Cells in Advanced Stages of Endogenously Arising B-cell Lymphoma: Implications for Therapeutic Cell Transfer
Published in Journal of immunotherapy (1997) (01-04-2012)“…During inflammation and in transplantable tumor models, natural killer (NK) cells are recruited to pathologic tissues and activated to produce proinflammatory…”
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Peritumoral administration of GPI-anchored TIMP-1 inhibits colon carcinoma growth in Rag-2 gamma chain-deficient mice
Published in Biological chemistry (01-09-2009)“…Exogenous application of recombinant TIMP-1 protein modified by addition of a glycosylphosphatidylinositol (GPI) anchor allows efficient insertion of the…”
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