Search Results - "Mueller, Natasha"

Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium by Verlinde, Christophe L M J, Fan, Erkang, Shibata, Sayaka, Zhang, Zongsheng, Sun, Zhihua, Deng, Wei, Ross, Jennifer, Kim, Jessica, Xiao, Liren, Arakaki, Tracy L, Bosch, Jürgen, Caruthers, Jonathan M, Larson, Eric T, Letrong, Isolde, Napuli, Alberto, Kelly, Angela, Mueller, Natasha, Zucker, Frank, Van Voorhis, Wesley C, Buckner, Frederick S, Merritt, Ethan A, Hol, Wim G J

“…The history of fragment-based drug discovery, with an emphasis on crystallographic methods, is sketched, illuminating various contributions, including our own,…”
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Low T3 Syndrome on Admission and Response to Nutritional Support in Malnourished Medical Inpatients by Müller, Natasha Anouschka, Kaegi-Braun, Nina, Durmisi, Mirsada, Gressies, Carla, Tribolet, Pascal, Stanga, Zeno, Mueller, Beat, Schuetz, Philipp

“…Abstract Context During illness, deiodination of thyroxine (T4) to triiodothyronine (T3) is downregulated. This is called “low T3 syndrome”, an adaptive…”
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Association of admission cortisol levels with outcomes and treatment response in patients at nutritional risk: A secondary analysis of a randomized clinical trial by Durmisi, Mirsada, Kaegi-Braun, Nina, Müller, Natasha A., Wunderle, Carla, Tribolet, Pascal, Stanga, Zeno, Mueller, Beat, Schuetz, Philipp

“…INTRODUCTIONCortisol is a metabolically active stress hormone that may play a role in the pathogenesis of malnutrition. We studied the association between…”
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Pitfalls in the Detection of Insulinomas With Glucagon-Like Peptide-1 Receptor Imaging by Antwi, Kwadwo, Hepprich, Matthias, Müller, Natasha A., Reubi, Jean Claude, Fani, Melpomeni, Rottenburger, Christof, Nicolas, Guillaume, Kaul, Felix, Christ, Emanuel R., Wild, Damian

“…PURPOSEPhysiological pancreaticoduodenal uptake of radiolabeled exendin-4 in Brunner glands of the proximal duodenum is the most common pitfall for false…”
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Screening a fragment cocktail library using ultrafiltration by Shibata, Sayaka, Zhang, Zhongsheng, Korotkov, Konstantin V., Delarosa, Jaclyn, Napuli, Alberto, Kelley, Angela M., Mueller, Natasha, Ross, Jennifer, Zucker, Frank H., Buckner, Frederick S., Merritt, Ethan A., Verlinde, Christophe L. M. J., Van Voorhis, Wesley C., Hol, Wim G. J., Fan, Erkang

“…Ultrafiltration provides a generic method to discover ligands for protein drug targets with millimolar to micromolar K d , the typical range of fragment-based…”
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The structure of Plasmodium vivax phosphatidylethanolamine-binding protein suggests a functional motif containing a left-handed helix by Arakaki, Tracy, Neely, Helen, Boni, Erica, Mueller, Natasha, Buckner, Frederick S., Van Voorhis, Wesley C., Lauricella, Angela, DeTitta, George, Luft, Joseph, Hol, Wim G. J., Merritt, Ethan A.

“…The structure of a putative Raf kinase inhibitor protein (RKIP) homolog from the eukaryotic parasite Plasmodium vivax has been studied to a resolution of 1.3 Å…”
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