Search Results - "Mueller, Lauren E."

Dopamine transients do not act as model-free prediction errors during associative learning by Sharpe, Melissa J., Batchelor, Hannah M., Mueller, Lauren E., Yun Chang, Chun, Maes, Etienne J. P., Niv, Yael, Schoenbaum, Geoffrey

“…Dopamine neurons are proposed to signal the reward prediction error in model-free reinforcement learning algorithms. This term represents the unpredicted or…”
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BRG1 in the Nucleus Accumbens Regulates Cocaine-Seeking Behavior by Wang, Zi-Jun, Martin, Jennifer A, Mueller, Lauren E, Caccamise, Aaron, Werner, Craig T, Neve, Rachael L, Gancarz, Amy M, Li, Jun-Xu, Dietz, David M

“…Abstract Background Drug addiction is defined as a chronic disease characterized by compulsive drug seeking and episodes of relapse despite prolonged periods…”
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A novel role for the actin-binding protein drebrin in regulating opiate addiction by Martin, Jennifer A., Werner, Craig T., Mitra, Swarup, Zhong, Ping, Wang, Zi-Jun, Gobira, Pedro H., Stewart, Andrew. F., Zhang, Jay, Erias, Kyra, Siemian, Justin N., Hagarty, Devin, Mueller, Lauren E., Neve, Rachael L., Li, Jun-Xu, Chandra, Ramesh, Dietz, Karen C., Lobo, Mary Kay, Gancarz, Amy M., Yan, Zhen, Dietz, David M.

“…Persistent transcriptional and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribute to the long-lasting behavioral…”
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Activin receptor signaling regulates cocaine-primed behavioral and morphological plasticity by Gancarz, Amy M, Wang, Zi-Jun, Schroeder, Gabrielle L, Damez-Werno, Diane, Braunscheidel, Kevin M, Mueller, Lauren E, Humby, Monica S, Caccamise, Aaron, Martin, Jennifer A, Dietz, Karen C, Neve, Rachael L, Dietz, David M

“…Gancarz et al . identify Activin-receptor signaling—including the downstream transcription factor Smad3—as an intracellular signaling pathway that is regulated…”
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DISC1 signaling in cocaine addiction: Towards molecular mechanisms of co-morbidity by Gancarz, Amy, Jouroukhin, Yan, Saito, Atsushi, Shevelkin, Alexey, Mueller, Lauren E., Kamiya, Atsushi, Dietz, David M., Pletnikov, Mikhail V.

“…•Cocaine self-administration up-regulates DISC1 expression in the nucleus accumbens.•DISC1 knockdown in the nucleus accumbens increases cocaine…”
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Dopamine transients are sufficient and necessary for acquisition of model-based associations by Sharpe, Melissa J, Chang, Chun Yun, Liu, Melissa A, Batchelor, Hannah M, Mueller, Lauren E, Jones, Joshua L, Niv, Yael, Schoenbaum, Geoffrey

“…Learning to predict reward is thought to be driven by dopaminergic prediction errors, which reflect discrepancies between actual and expected value. Here the…”
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Spatial Representations in Rat Orbitofrontal Cortex by Wikenheiser, Andrew M, Gardner, Matthew P H, Mueller, Lauren E, Schoenbaum, Geoffrey

“…The orbitofrontal cortex (OFC) and hippocampus share striking cognitive and functional similarities. As a result, both structures have been proposed to encode…”
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Past experience shapes the neural circuits recruited for future learning by Sharpe, Melissa J., Batchelor, Hannah M., Mueller, Lauren E., Gardner, Matthew P. H., Schoenbaum, Geoffrey

“…Experimental research controls for past experience, yet prior experience influences how we learn. Here, we tested whether we could recruit a neural population…”
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Dopaminergic prediction errors in the ventral tegmental area reflect a multithreaded predictive model by Takahashi, Yuji K., Stalnaker, Thomas A., Mueller, Lauren E., Harootonian, Sevan K., Langdon, Angela J., Schoenbaum, Geoffrey

“…Dopamine neuron activity is tied to the prediction error in temporal difference reinforcement learning models. These models make significant simplifying…”
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Teneurin C-terminal associated peptide (TCAP)-1 attenuates the development and expression of naloxone-precipitated morphine withdrawal in male Swiss Webster mice by Mueller, Lauren E., Wexler, Roseanne S., Lovejoy, David A., Stein, Robert B., Slee, Andrew M.

“…Rationale Corticotropin-releasing factor (CRF), the apical stress-inducing hormone, exacerbates stress and addictive behaviors. TCAP-1 is a peptide that…”
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Prior Cocaine Use Alters the Normal Evolution of Information Coding in Striatal Ensembles during Value-Guided Decision-Making by Mueller, Lauren E, Sharpe, Melissa J, Stalnaker, Thomas A, Wikenheiser, Andrew M, Schoenbaum, Geoffrey

“…Substance use disorders (SUDs) are characterized by maladaptive behavior. The ability to properly adjust behavior according to changes in environmental…”
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Molecular Targets of Triple-Negative Breast Cancer: Where Do We Stand? by Newton, Emma E, Mueller, Lauren E, Treadwell, Scout M, Morris, Cindy A, Machado, Heather L

“…Triple-negative breast cancer (TNBC) is a highly aggressive form of breast cancer. Due to its heterogeneity and lack of hormone receptor expression, this…”
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Clinical outcomes and tumor microenvironment response to radiofrequency ablation therapy: a systematic review and meta-analysis by Mueller, Lauren E, Issa, Peter P, Hussein, Mohammad Hosny, Elshazli, Rami M, Haidari, Muhib, Errami, Youssef, Shama, Mohamed, Fawzy, Manal S, Kandil, Emad, Toraih, Eman

“…Radiofrequency ablation (RFA) utilizes minimally invasive high-energy current to precisely ablate tumor cells. It has been utilized in many cancer types…”
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Elevated potassium provides an ionic mechanism for deep brain stimulation in the hemiparkinsonian rat by Sutton, Alexander C., Yu, Wilson, Calos, Megan E., Mueller, Lauren E., Berk, Matthew, Shim, Jenny, Molho, Eric S., Brotchie, Jonathan M., Carlen, Peter L., Shin, Damian S.

“…The mechanism of high‐frequency stimulation used in deep brain stimulation (DBS) for Parkinson's disease (PD) has not been completely elucidated. Previously,…”
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Author Correction: Dopamine transients are sufficient and necessary for acquisition of model-based associations by Sharpe, Melissa J, Chang, Chun Yun, Liu, Melissa A, Batchelor, Hannah M, Mueller, Lauren E, Jones, Joshua L, Niv, Yael, Schoenbaum, Geoffrey

“…In the version of this article initially published, the laser activation at the start of cue X in experiment 1 was described in the first paragraph of the…”
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Correction: Corrigendum: Dopamine transients are sufficient and necessary for acquisition of model-based associations by Sharpe, Melissa J, Chang, Chun Yun, Liu, Melissa A, Batchelor, Hannah M, Mueller, Lauren E, Jones, Joshua L, Niv, Yael, Schoenbaum, Geoffrey

“…Nat. Neurosci. 20, 735–742 (2017); published online 3 April 2017; corrected online 10 April 2017; corrected after print 5 May 2017 In the version of this…”
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Erratum: Corrigendum: Dopamine transients are sufficient and necessary for acquisition of model-based associations by Sharpe, Melissa J, Chang, Chun Yun, Liu, Melissa A, Batchelor, Hannah M, Mueller, Lauren E, Jones, Joshua L, Niv, Yael, Schoenbaum, Geoffrey

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Corrigendum: Dopamine transients are sufficient and necessary for acquisition of model-based associations by Sharpe, Melissa J, Chang, Chun Yun, Liu, Melissa A, Batchelor, Hannah M, Mueller, Lauren E, Jones, Joshua L, Niv, Yael, Schoenbaum, Geoffrey

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SEMIOTICS IN ITALY: CESARE SEGRE, GIANFRANCO BETTETINI, PIER PAOLO PASOLINI, EMILIO GARRONI by MUELLER, LAUREN E

“…As Terrence Hawkes points out, the concept of structuralism has a distinctly French "air" about it but did not, however, develop from a strictly French base…”
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SEMIOTICS IN ITALY: CESARE SEGRE, GIANFRANCO BETTETINI, PIER PAOLO PASOLINI, EMILIO GARRONI by MUELLER, LAUREN E

“…As Terrence Hawkes points out, the concept of structuralism has a distinctly French "air" about it but did not, however, develop from a strictly French base…”
Get full text