Search Results - "Mueller, BM"

Deficiency of plasminogen receptor, Plg‐RKT, causes defects in plasminogen binding and inflammatory macrophage recruitment in vivo by Miles, L. A., Baik, N., Lighvani, S., Khaldoyanidi, S., Varki, N. M., Bai, H., Mueller, B.M., Parmer, R. J.

“…Essentials Plg‐RKT is a novel integral membrane plasminogen receptor. The functions of Plg‐RKT in vivo are not known. Plg‐RKT is a key player in macrophage…”
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Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway by Riewald, Matthias, Petrovan, Ramona J., Donner, Aaron, Mueller, Barbara M., Ruf, Wolfram

“…The coagulant and inflammatory exacerbation in sepsis is counterbalanced by the protective protein C (PC) pathway. Activated PC (APC) was shown to use the…”
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Correction to “Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast CancerLink to Patient Survival, Hormone Receptor Status, and Metabolic Profiling” by Brockmöller, Scarlet F., Bucher, Elmar, Müller, Berit M., Budczies, Jan, Hilvo, Mika, Griffin, Julian L., Orešič, Matej, Kallioniemi, Olli, Iljin, Kristiina, Loibl, Sibylle, Darb-Esfahani, Silvia, Sinn, Bruno V., Klauschen, Frederick, Prinzler, Judith, Bangemann, Nikola, Ismaeel, Fakher, Fiehn, Oliver, Dietel, Manfred, Denkert, Carsten

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Regulation of angiogenesis by tissue factor cytoplasmic domain signaling by Friedlander, Martin, Ruf, Wolfram, Belting, Mattias, Dorrell, Michael I, Sandgren, Staffan, Aguilar, Edith, Ahamed, Jasimuddin, Dorfleutner, Andrea, Carmeliet, Peter, Mueller, Barbara M

“…Hemostasis initiates angiogenesis-dependent wound healing, and thrombosis is frequently associated with advanced cancer. Although activation of coagulation…”
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Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis by Shi, Xiaoli, Gangadharan, Beena, Brass, Lawrence F, Ruf, Wolfram, Mueller, Barbara M

“…The effects of the pleiotropic serine protease thrombin on tumor cells are commonly thought to be mediated by the thrombin receptor protease-activated receptor…”
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Requirement for binding of catalytically active factor VIIa in tissue factor-dependent experimental metastasis by Mueller, B M, Ruf, W

“…Tissue factor (TF), the initiating cell surface receptor of the coagulation cascade, plays important roles in embryogenesis, angiogenesis, and tumor cell…”
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Integrin Activation Controls Metastasis in Human Breast Cancer by Felding-Habermann, Brunhilde, O'Toole, Timothy E., Smith, Jeffrey W., Fransvea, Emilia, Ruggeri, Zaverio M., Ginsberg, Mark H., Hughes, Paul E., Pampori, Nisar, Shattil, Sanford J., Saven, Alan, Mueller, Barbara M.

“…Metastasis is the primary cause of death in human breast cancer. Metastasis to bone, lungs, liver, and brain involves dissemination of breast cancer cells via…”
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Carcinoma and Stromal Enzyme Activity Profiles Associated with Breast Tumor Growth in vivo by Jessani, Nadim, Humphrey, Mark, McDonald, W. Hayes, Niessen, Sherry, Masuda, Kim, Gangadharan, Beena, Yates, John R., Mueller, Barbara M., Cravatt, Benjamin F., Vogt, Peter K.

“…Cancer research depends on the use of human cell lines for both the in vitro (culture) and in vivo (xenograft) analysis of tumor progression and treatment…”
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A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-Binding Protein 280 by Ott, Ilka, Fischer, Edgar G., Miyagi, Yohei, Mueller, Barbara M., Ruf, Wolfram

“…Tissue factor (TF), the protease receptor initiating the coagulation system, functions in vascular development, angiogenesis, and tumor cell metastasis by…”
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Long-term outcome in COPD patients with pneumonic and nonpneumonic exacerbation: a 6-year prospective follow-up study by Grolimund, EG, Kutz, AK, Alan, MA, Mueller, BM, Schuetz, PS

“…Keywords: Receiver Operating Characteristic Curve, Improve Patient Care, Blood Marker, Discharge Level, Baseline Predictor…”
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Abstract PD06-01: Automated computational Ki67 scoring in the GeparTrio breast cancer study cohort by Klauschen, F, Wienert, S, Blohmer, J-U, Mueller, BM, Eiermann, W, Gerber, B, Tesch, H, Hilfrich, J, Huober, J, Fehm, T, Barinoff, J, Jackisch, C, Erbstoesser, E, Loibl, S, Denkert, C, von Minckwitz, G

“…Abstract Background: Scoring proliferation through Ki67-immunohistochemistry is an important component in predicting therapy response to chemotherapy in breast…”
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Plasminogen Activation/Plasmin in Rheumatoid Arthritis: Matrix Degradation and More by Judex, Martin O., Mueller, Barbara M.

“…Rheumatoid arthritis (RA) is one of the most common and most debilitating joint diseases, producing high personal, social, and economic costs. 1,2 Patients…”
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Low-density-lipoprotein-receptor-related protein (LRP) interacts with a GTP-binding protein by Goretzki, L, Mueller, B M

“…The low-density-lipoprotein-receptor-related protein (LRP) binds and internalizes numerous ligands, including lipoproteins, proteinase-inhibitor complexes and…”
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Estrogen induces lung metastasis through a host compartment-specific response by BANKA, Carole L, LUND, Caren V, NGUYEN, Mai T. N, PAKCHOIAN, Andrew J, MUELLER, Barbara M, ELICEIRI, Brian P

“…Direct proliferative effects of estrogen (E(2)) on estrogen receptor-positive tumors are well documented; however, the potential for E(2) to mediate effects…”
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Urokinase-Type Plasminogen Activator Binding to Its Receptor Stimulates Tumor Cell Migration by Enhancing Integrin-Mediated Signal Transduction by Yebra, Mayra, Goretzki, Lothar, Pfeifer, Michelle, Mueller, Barbara M.

“…Urokinase-type plasminogen activator (uPA) and its receptor (uPAR) participate in matrix degradation and cell migration by focusing proteolysis and functioning…”
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The Urokinase-Type Plasminogen Activator Receptor, a GPI-Linked Protein, Is Localized in Caveolae by Stahl, Andreas, Mueller, Barbara M.

“…The urokinase plasminogen activator receptor (uPAR), a glycosylphosphatidylinositol-linked glycoprotein, plays a central role in the regulation of pericellular…”
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Tissue factor signaling by Ruf, W, Mueller, B M

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Tumor cell adhesion and migration supported by interaction of a receptor-protease complex with its inhibitor by Fischer, E G, Riewald, M, Huang, H Y, Miyagi, Y, Kubota, Y, Mueller, B M, Ruf, W

“…Tissue factor (TF), the cell-surface receptor for coagulation factor VIIa, supports metastasis. Equally important for this process are (a) interactions of the…”
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Binding of urokinase to its receptor promotes migration and invasion of human melanoma cells in vitro by STAHL, A, MUELLER, B. M

“…Previously, we reported that urokinase-type plasminogen activator (uPA) plays a pivotal role in extracellular matrix dissolution by malignant melanoma cells…”
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Expression of Tissue Factor by Melanoma Cells Promotes Efficient Hematogenous Metastasis by Mueller, Barbara M., Reisfeld, Ralph A., Edgington, Thomas S., Ruf, Wolfram

“…Metastasis is a multistep process which requires highly adapted interactions of tumor cells with host target organs. Compared with nonmetastatic cells,…”
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