Search Results - "Muehlenweg, B"

Inhibition of urokinase plasminogen activator with a novel enzyme inhibitor, wxc-340, ameliorates endotoxin and surgery-accelerated growth of murine metastases by KILLEEN, S. D, ANDREWS, E. J, WANG, J. H, WU, T, SCHMALIX, W, MUEHLENWEG, B, REDMOND, H. P

“…The urokinase plasminogen activator (u-PA) is intimately associated with tumour invasion and metastases. Surgery facilitates accelerated metastatic tumour…”
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Clinical relevance of matrix metalloproteinase-13 determined with a new highly specific and sensitive ELISA in ascitic fluid of advanced ovarian carcinoma patients by Hantke, Bernd, Harbeck, Nadia, Schmalfeldt, Barbara, Claes, Ingeborg, Hiller, Oliver, Luther, Marc-Oliver, Welk, Anita, Kuhn, Walther, Schmitt, Manfred, Tschesche, Harald, Muehlenweg, Bernd

“…Matrix metalloproteinases (MMPs) are involved in many physiological and pathophysiological processes, including tumor cell invasion and metastasis. For one…”
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Inhibition of the invasion capacity of carcinoma cells by WX‐UK1, a novel synthetic inhibitor of the urokinase‐type plasminogen activator system by Ertongur, Suna, Lang, Stephan, Mack, Brigitte, Wosikowski, Katja, Muehlenweg, Bernd, Gires, Olivier

“…The overall survival rate of patients suffering from carcinomas has remained poor and nearly unchanged over the last decades. This is mainly due to the…”
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High-affinity urokinase-derived cyclic peptides inhibiting urokinase/urokinase receptor-interaction: effects on tumor growth and spread by Sato, Sumito, Kopitz, Charlotte, Schmalix, Wolfgang A, Muehlenweg, Bernd, Kessler, Horst, Schmitt, Manfred, Krüger, Achim, Magdolen, Viktor

“…Urokinase-type plasminogen activator (uPA) binds with high affinity to its specific cell surface receptor (uPAR) (CD87) via a well-defined sequence within the…”
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The solution structure and dynamics of human neutrophil gelatinase-associated lipocalin by Coles, M, Diercks, T, Muehlenweg, B, Bartsch, S, Zölzer, V, Tschesche, H, Kessler, H

“…Human neutrophil gelatinase-associated lipocalin (HNGAL) is a member of the lipocalin family of extracellular proteins that function as transporters of small,…”
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Interference with the urokinase plasminogen activator system: a promising therapy concept for solid tumours by Muehlenweg, B, Sperl, S, Magdolen, V, Schmitt, M, Harbeck, N

“…There is abundant evidence that the plasminogen activator (PA) system with its key components uPA (urokinase-type plasminogen activator), its cell surface…”
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Identification of markers for the selection of patients undergoing renal cell carcinoma-specific immunotherapy by Seliger, Barbara, Menig, Matthias, Lichtenfels, Rudolf, Atkins, Derek, Bukur, Jürgen, Halder, Thomas M., Kersten, Michael, Harder, Alois, Ackermann, Angelika, Beck, Joachim, Muehlenweg, Bernd, Brenner, Walburgis, Melchior, Sebastian, Kellner, Roland, Lottspeich, Friedrich

“…Renal cell carcinoma (RCC) represents the most common malignant tumor in the kidney and is resistant to conventional therapies. The diagnosis of RCC is often…”
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Bacterial endotoxin enhances colorectal cancer cell adhesion and invasion through TLR-4 and NF-κB dependent activation of the urokinase plasminogen activator system by Killeen, S.D., Wang, J.H., Andrews, E.J., Schmalix, W., Muehlenweg, B., Redmond, H.P.

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Identification of a novel urokinase receptor splice variant and its prognostic relevance in breast cancer by Luther, Thomas, Kotzsch, Matthias, Meye, Axel, Langerholc, Thomaz, Füssel, Susanne, Olbricht, Natalie, Albrecht, Sybille, Ockert, Detlev, Muehlenweg, Bernd, Friedrich, Katrin, Grosser, Marianne, Schmitt, Manfred, Baretton, Gustavo, Magdolen, Viktor

“…The cellular receptor for urokinase-type plasminogen activator, uPAR, plays a central role in both cell surface-associated proteolysis and cellular adhesion…”
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Induction of tumor cell death by high hydrostatic pressure as a novel supporting technique in orthopedic surgery by Diehl, Peter, Schmitt, Manfred, Blümelhuber, Gerrit, Frey, Benjamin, Van Laak, Susanne, Fischer, Steffen, Muehlenweg, Bernd, Meyer-Pittroff, Roland, Gollwitzer, Hans, Mittelmeier, Wolfram

“…As vegetative forms of microorganisms are impaired by high hydrostatic pressure (HHP) in the range of 400-600 MPa, the non-thermal inactivation of vegetative…”
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A novel type of bifunctional inhibitor directed against proteolytic activity and receptor/ligand interaction. Cystatin with a urokinase receptor binding site by Muehlenweg, B, Assfalg-Machleidt, I, Parrado, S G, Bürgle, M, Creutzburg, S, Schmitt, M, Auerswald, E A, Machleidt, W, Magdolen, V

“…Cancer invasion and metastasis is a process requiring a coordinated series of (anti-)adhesive, migratory, and pericellular proteolytic events involving various…”
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Protein expression of MMP-13, uPA, and PAI-1 in pseudocapsular and interface tissue around implants of loose artificial hip joints and in osteoarthritis by Diehl, Peter, Hantke, Bernd, Hennig, Michael, Tschesche, Harald, Mittelmeier, Wolfram, Schmitt, Manfred, Muehlenweg, Bernd

“…Matrix metalloproteinase 13 (MMP-13), urokinase type plasminogen activator (uPA), and plasminogen activator inhibitor type-1 (PAI-1) have been reported to be…”
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Natural and synthetic inhibitors of the tumor-associated serine protease urokinase-type plasminogen activator by Magdolen, V, Arroyo de Prada, N, Sperl, S, Muehlenweg, B, Luther, T, Wilhelm, O G, Magdolen, U, Graeff, H, Reuning, U, Schmitt, M

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Interaction of plasminogen activator inhibitor type‐1 (PAI‐1) with vitronectin: Characterization of different PAI‐1 mutants by Arroyo De Prada, Nuria, Schroeck, Florian, Sinner, Eva‐Kathrin, Muehlenweg, Bernd, Twellmeyer, Jens, Sperl, Stefan, Wilhelm, Olaf G., Schmitt, Manfred, Magdolen, Viktor

“…The serpin plasminogen activator inhibitor type 1 (PAI‐1) plays an important role in physiological processes such as thrombolysis and fibrinolysis, as well as…”
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Epitope Mapping of Monoclonal Antibodies Directed to PAI-1 Using PAI-1/PAI-2 Chimera and PAI-1-Derived Synthetic Peptides by Muehlenweg, Bernd, Guthaus, Elke, de Prada, Nuria Arroyo, Schmitt, Manfred, Schmiedeberg, Niko, Kotzsch, Matthias, Creutzburg, Sabine, Kramer, Michael D, Kessler, Horst, Wilhelm, Olaf G, Magdolen, Viktor

“…Plasminogen activator inhibitor type-1 is a key regulatory protein of the fibrinolytic system that is involved in a variety of physiological and…”
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