Search Results - "Mudgal, Rajat"

Prospects for mucosal vaccine: shutting the door on SARS-CoV-2 by Mudgal, Rajat, Nehul, Sanketkumar, Tomar, Shailly

“…The sudden emergence of a highly transmissible and pathogenic coronavirus SARS-CoV-2 in December 2019 from China and its rapid global spread has posed an…”
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Xanthine Oxidoreductase in the Pathogenesis of Endothelial Dysfunction: An Update by Mudgal, Rajat, Singh, Sanjiv

“…Xanthine oxidoreductase (XOR) is a rate-limiting enzyme in the formation of uric acid (UA) and is involved in the generation of reactive oxygen species (ROS)…”
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Bioactive components to inhibit foam cell formation in atherosclerosis by Singh, Sanjiv, Changkija, Senti, Mudgal, Rajat, Ravichandiran, V.

“…Background The production of lipid-laden cells in macrophages after significant ingestion of oxidized low-density lipoprotein is considered the most critical…”
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The neuroprotective effect of ascorbic acid against imidacloprid-induced neurotoxicity and the role of HO-1 in mice by Mudgal, Rajat, Sharma, Satyam, Singh, Sanjiv, Ravichandiran, V

“…Imidacloprid (IMI) is not only a neurotoxic agricultural pesticide but also a possible food contaminant. The aims of this study were to (1) explore the…”
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Biomechanical Role of Epsin in Influenza A Virus Entry by Joseph, Jophin G, Mudgal, Rajat, Lin, Shan-Shan, Ono, Akira, Liu, Allen P

“…Influenza A virus (IAV) utilizes clathrin-mediated endocytosis for cellular entry. Membrane-bending protein epsin is a cargo-specific adaptor for IAV entry…”
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Inhibition of Chikungunya virus by an adenosine analog targeting the SAM‐dependent nsP1 methyltransferase by Mudgal, Rajat, Mahajan, Supreeti, Tomar, Shailly

“…Alphaviruses, including Chikungunya (CHIKV) and Venezuelan equine encephalitis virus (VEEV), are among the leading causes of recurrent epidemics all over the…”
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A Glu-Glu-Tyr Sequence in the Cytoplasmic Tail of the M2 Protein Renders Influenza A Virus Susceptible to Restriction of the Hemagglutinin-M2 Association in Primary Human Macrophages by Bedi, Sukhmani, Mudgal, Rajat, Haag, Amanda, Ono, Akira

“…Influenza A virus (IAV) assembly at the plasma membrane is orchestrated by at least five viral components, including hemagglutinin (HA), neuraminidase (NA),…”
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Development of an ELISA assay for screening inhibitors against divalent metal ion dependent alphavirus capping enzyme by Kaur, Ramanjit, Mudgal, Rajat, Narwal, Manju, Tomar, Shailly

“…•Development of a non-radioactive ELISA assay for CHIKV nsP1 enzymatic activity.•ICP-MS unraveled the presence of Mg2+ ions in purified nsP1.•The D63 A mutant…”
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Glycan-dependent chikungunya viral infection divulged by antiviral activity of NAG specific chi-like lectin by Kaur, Ramanjit, Neetu, Mudgal, Rajat, Jose, Joyce, Kumar, Pravindra, Tomar, Shailly

“…Highly pathogenic alphaviruses display complex glycans on their surface. These glycans play a crucial role in viral pathogenesis by facilitating glycan-host…”
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Alphavirus antivirals targeting RNA‐dependent RNA polymerase domain of nsP4 divulged using surface plasmon resonance by Pareek, Akshay, Kumar, Ravi, Mudgal, Rajat, Neetu, Neetu, Sharma, Monica, Kumar, Pravindra, Tomar, Shailly

“…Alphaviruses are continuously re‐emerging and pose a global threat to human health and currently no antiviral drug is commercially available for alphaviral…”
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Chikungunya virus inhibition by peptidomimetic inhibitors targeting virus-specific cysteine protease by Singh, Harvijay, Mudgal, Rajat, Narwal, Manju, Kaur, Ramanjit, Singh, Vedita Anand, Malik, Anjali, Chaudhary, Madhulika, Tomar, Shailly

“…Chikungunya virus (CHIKV), a mosquito-borne pathogenic virus that reemerged and caused epidemic in the Indian Ocean island of La Réunion, is a potential public…”
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Selective Estrogen Receptor Modulators Limit Alphavirus Infection by Targeting the Viral Capping Enzyme nsP1 by Mudgal, Rajat, Bharadwaj, Chandrima, Dubey, Aakriti, Choudhary, Shweta, Nagarajan, Perumal, Aggarwal, Megha, Ratra, Yashika, Basak, Soumen, Tomar, Shailly

“…Alphaviruses cause animal or human diseases that are characterized by febrile illness, debilitating arthralgia, or encephalitis. Selective estrogen receptor…”
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Evaluation of antiviral activity of piperazine against Chikungunya virus targeting hydrophobic pocket of alphavirus capsid protein by Aggarwal, Megha, Kaur, Ramanjit, Saha, Amrita, Mudgal, Rajat, Yadav, Ravi, Dash, Paban Kumar, Parida, Manmohan, Kumar, Pravindra, Tomar, Shailly

“…Small heterocyclic molecules such as piperazine are potential pharmacotherapeutic agents and binding of these molecules to the hydrophobic pocket of capsid…”
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Analysis of tweets to find the basis of popularity based on events semantic similarity by Mudgal, Rajat Kumar, Niyogi, Rajdeep, Milani, Alfredo, Franzoni, Valentina

“…PurposeThe purpose of this paper is to propose and experiment a framework for analysing the tweets to find the basis of popularity of a person and extract the…”
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Sentiment Extraction and Classification for the Analysis of Users Interest in Tweets by Milani, Alfredo, Rajdeep, Niyogi, Mangal, Nimita, Franzoni, Valentina

“…PurposeThis paper aims to propose an approach for the analysis of user interest based on tweets, which can be used in the design of user recommendation…”
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