Search Results - "Muddineti, Omkara Swami"
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Transferrin-Modified Vitamin-E/Lipid Based Polymeric Micelles for Improved Tumor Targeting and Anticancer Effect of Curcumin
Published in Pharmaceutical research (01-05-2018)“…Purpose Transferrin receptor (TfR) is up-regulated in various malignant tumors not only to meet the iron requirement, but also to increase the cell survival…”
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Curcumin-loaded chitosan-cholesterol micelles: evaluation in monolayers and 3D cancer spheroid model
Published in Nanomedicine (London, England) (01-06-2017)“…To improve the bioavailability and anticancer potential of curcumin by using a cholesterol-conjugated chitosan micelle. Cholesterol was conjugated to chitosan…”
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Cholesterol-conjugated poly(D, L-lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in cancer therapy
Published in Drug delivery (01-01-2017)“…Polymeric micelles have been widely explored preclinically as suitable delivery systems for poorly soluble chemotherapeutic drugs in cancer therapy. The…”
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Current trends in using polymer coated gold nanoparticles for cancer therapy
Published in International journal of pharmaceutics (30-04-2015)“…[Display omitted] The interest in using the polymer-coated gold nanoparticles (P-AuNPs) for various biomedical applications, including the delivery of…”
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Current trends in the use of vitamin E-based micellar nanocarriers for anticancer drug delivery
Published in Expert opinion on drug delivery (03-06-2017)“…Owing to the complexity of cancer pathogenesis, conventional chemotherapy can be an inadequate method of killing cancer cells effectively. Nanoparticle-based…”
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Cholesterol-grafted chitosan micelles as a nanocarrier system for drug-siRNA co-delivery to the lung cancer cells
Published in International journal of biological macromolecules (15-10-2018)“…Combined delivery of a therapeutic small interfering RNA (siRNA) and a chemotherapeutic agent to cancer cells is promising as anticancer therapy, which could…”
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Curcumin Delivery by Poly(Lactide)-Based Co-Polymeric Micelles: An In Vitro Anticancer Study
Published in Pharmaceutical research (01-04-2016)“…Purpose This work describes the synthesis of block co-polymeric micelles, methoxy-poly(ethylene glycol)-poly(D,L-lactide) (mPEG-PLA) to encapsulate Curcumin…”
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Transferrin-anchored poly(lactide) based micelles to improve anticancer activity of curcumin in hepatic and cervical cancer cell monolayers and 3D spheroids
Published in International journal of biological macromolecules (01-09-2018)“…In recent years, actively targeted drug delivery systems have been utilized in pre-clinical studies for site-specific delivery of drugs, which reduces…”
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d‑α-Tocopheryl Succinate/Phosphatidyl Ethanolamine Conjugated Amphiphilic Polymer-Based Nanomicellar System for the Efficient Delivery of Curcumin and To Overcome Multiple Drug Resistance in Cancer
Published in ACS applied materials & interfaces (24-05-2017)“…Nanomedicines have emerged as a promising treatment strategy for cancer. Multiple drug resistance due to overexpression of various drug efflux transporters and…”
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Vitamin-E/lipid based PEGylated polymeric micellar doxorubicin to sensitize doxorubicin-resistant cells towards treatment
Published in Reactive & functional polymers (01-01-2019)“…Multiple drug resistance (MDR) hampers therapeutic outcome of many anti-cancer drugs, including doxorubicin (Dox) by reducing their intracellular concentration…”
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Lipid and poly (ethylene glycol)-conjugated bi-functionalized chlorine e6 micelles for NIR-light induced photodynamic therapy
Published in Photodiagnosis and photodynamic therapy (01-03-2020)“…[Display omitted] •Ce6 was linked to PEG, DOPE to form an amphiphilic polymer, DP-Ce6.•The amphiphilic polymer self-assembled to form polymeric micelles,…”
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Evaluation of Anti-Tumor Efficacy of Vorinostat Encapsulated Self-Assembled Polymeric Micelles in Solid Tumors
Published in AAPS PharmSciTech (01-10-2018)“…Vorinostat (VOR), a potent HDAC inhibitor, suffers from low solubility and poor absorption, which hinders its successful application in therapy, especially in…”
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Erratum to: Curcumin Delivery by Poly(Lactide)-Based Co-Polymeric Micelles: An In Vitro Anticancer Study
Published in Pharmaceutical research (01-07-2016)Get full text
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Cholesterol and vitamin E-conjugated PEGylated polymeric micelles for efficient delivery and enhanced anticancer activity of curcumin: evaluation in 2D monolayers and 3D spheroids
Published in Artificial cells, nanomedicine, and biotechnology (01-01-2018)“…A newly synthesized PEGylated cholesterol/α-tocopheryl succinate (α-TOS) linked polymer (CV) was self-assembled and loaded with curcumin to form a micellar…”
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