Search Results - "Mudavath, Shyam Lal"
-
1
Self-assembled nanomicelles for oral delivery of luteolin utilizing the intestinal lymphatic pathway to target pancreatic cancer
Published in Nanoscale (18-04-2024)“…Pancreatic cancer is one of the major cause of cancer-related deaths worldwide, and is mainly associated with carcinomas of the pancreatic tissue. Current…”
Get more information
Journal Article -
2
Modified solid lipid nanoparticles encapsulated with Amphotericin B and Paromomycin: an effective oral combination against experimental murine visceral leishmaniasis
Published in Scientific reports (22-07-2020)“…The development of an effective oral therapeutics is an immediate need for the control and elimination of visceral leishmaniasis (VL). We exemplify the…”
Get full text
Journal Article -
3
Dual Drug Delivery for Augmenting Bacterial Wound Complications via Tailored Ultradeformable Carriers
Published in Bioconjugate chemistry (19-06-2024)“…Addressing the complex challenge of healing of bacterially infected wounds, this study explores the potential of lipid nanomaterials, particularly advanced…”
Get full text
Journal Article -
4
Envisioning the innovations in nanomedicine to combat visceral leishmaniasis: for future theranostic application
Published in Nanomedicine (London, England) (01-07-2019)“…Visceral leishmaniasis (VL) is a life-threatening parasitic disease affecting impoverished people of the developing world; and much effort has been spent on…”
Get full text
Journal Article -
5
Sensible graphene oxide differentiates macrophages and Leishmania : a bio-nano interplay in attenuating intracellular parasite
Published in RSC advances (22-07-2020)“…is an obligate intracellular protozoan parasite, which resides in human macrophage vacuoles that are referred to as parasitophorus vacuoles. Amphotericin B…”
Get full text
Journal Article -
6
Immunotherapy and immunochemotherapy in combating visceral leishmaniasis
Published in Frontiers in medicine (17-05-2023)“…Visceral leishmaniasis (VL), a vector-borne disease, is caused by an obligate intramacrophage, kinetoplastid protozoan parasite of the genus . Globally, VL is…”
Get full text
Journal Article -
7
Nanodiagnostics in leishmaniasis: A new frontiers for early elimination
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-03-2021)“…Visceral leishmaniasis (VL) is still a major public health concern in developing countries having the highest outbreak and mortality potential. While the…”
Get full text
Journal Article -
8
Recuperating Biopharmaceutical Aspects of Amphotericin B and Paromomycin Using a Chitosan Functionalized Nanocarrier via Oral Route for Enhanced Anti-leishmanial Activity
Published in Frontiers in cellular and infection microbiology (15-10-2020)“…The design and development of new pharmaceutical formulations for the existing anti-leishmanial is a new strategic alternate to improve efficacy and safety…”
Get full text
Journal Article -
9
Evaluation of Safety and Antileishmanial Efficacy of Amine Functionalized Carbon-Based Composite Nanoparticle Appended With Amphotericin B: An in vitro and Preclinical Study
Published in Frontiers in chemistry (03-07-2020)“…Visceral leishmaniasis (VL) has been a major health concern in the developing world, primarily affecting impoverished people. It is caused by a protozoan…”
Get full text
Journal Article -
10
Comparative Evaluation of Blood and Serum Samples in Rapid Immunochromatographic Tests for Visceral Leishmaniasis
Published in Journal of Clinical Microbiology (01-12-2013)“…Classifications Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text
Journal Article -
11
Characterization and evaluation of amine-modified graphene amphotericin B for the treatment of visceral leishmaniasis: in vivo and in vitro studies
Published in Drug design, development and therapy (01-01-2014)“…Amphotericin B (AmB) has been the first-line treatment for visceral leishmaniasis (VL), a neglected protozoan disease, especially in regions like Bihar, India,…”
Get full text
Journal Article -
12
Niacin-induced flushing: Mechanism, pathophysiology, and future perspectives
Published in Archives of biochemistry and biophysics (01-11-2024)“…Flushing is a typical physiological reaction to high emotional reactions. It is characterized by cutaneous vasodilation and a feeling of warmth and skin…”
Get full text
Journal Article -
13
Fabrication, physicochemical characterization and In vitro anticancer activity of nerolidol encapsulated solid lipid nanoparticles in human colorectal cell line
Published in Colloids and surfaces, B, Biointerfaces (01-07-2022)“…Nerolidol is a sesquiterpene that occurs naturally and possesses a diverse set of biological characteristics including anticancer activity but has limited…”
Get full text
Journal Article -
14
Transport mechanism of hydroxy-propyl-beta-cyclodextrin modified solid lipid nanoparticles across human epithelial cells for the oral absorption of antileishmanial drugs
Published in Biochimica et biophysica acta. General subjects (01-08-2022)“…In this study, the transport mechanism of fluorescently labeled hydroxypropyl beta-cyclodextrin (HPβ-CD) modified SLNs loaded with Amphotericin B (AmB) and…”
Get full text
Journal Article -
15
Enkephalins as a therapeutic intervention for visceral leishmaniasis
Published in Medical hypotheses (01-11-2020)“…Visceral leishmaniasis (VL) is a neglected tropical disease with high incidence of mortality and morbidity. The emergence of drug resistant parasites, severe…”
Get full text
Journal Article -
16
Role of STAT3 in the initiation, progression, proliferation and metastasis of breast cancer and strategies to deliver JAK and STAT3 inhibitors
Published in Life sciences (1973) (15-11-2022)“…INTRODUCTIONBreast cancer (BC) accounts for the majority of cancers among the female population. Anomalous activation of various signaling pathways has become…”
Get full text
Journal Article -
17
Organ-restricted delivery through stimuli-responsive nanocarriers for lung cancer therapy
Published in Life sciences (1973) (01-12-2022)“…Lung Cancer (LC) is the malignant tumor of the lungs which is defined by the unrestricted cell development in the lung tissues which if left untreated may…”
Get full text
Journal Article -
18
Folate receptor targeted NIR cleavable liposomal delivery system augment penetration and therapeutic efficacy in breast cancer
Published in Biochimica et biophysica acta. General subjects (01-09-2023)“…Liposomes are predominantly used sorts of nanocarriers for active a targeted delivery through surface functionalization using targeting ligand. The folate…”
Get full text
Journal Article -
19
-
20
Effervescent based nano-gas carrier enhanced the bioavailability of poorly aqueous soluble drug: A comprehensive mechanistic understanding
Published in Journal of drug delivery science and technology (01-03-2022)“…The low aqueous solubility of drug molecules is a considerable hurdle to produce the desired pharmacological effect through any biological route of drug…”
Get full text
Journal Article