Search Results - "Můnz, Christian"

Latency and lytic replication in Epstein–Barr virus-associated oncogenesis by Münz, Christian

“…Epstein–Barr virus (EBV) was the first tumour virus identified in humans. The virus is primarily associated with lymphomas and epithelial cell cancers. These…”
Get full text

Altered EBV specific immune control in multiple sclerosis by Münz, Christian

“…Since the 1980s it is known that immune responses to the Epstein-Barr virus (EBV) are elevated in multiple sclerosis (MS) patients. Recent seroepidemiologial…”
Get full text

Immune control of human γ-herpes infections by Münz, Christian

“…Recent evidence suggests that infection with the Epstein Barr virus (EBV) initiates a prodromal phase of multiple sclerosis (MS) in individuals with genetic…”
Get full text

Autophagy proteins influence endocytosis for MHC restricted antigen presentation by Münz, Christian

“…T cells of the adaptive immune system monitor protein degradation products via their presentation on major histocompatibility complex (MHC) molecules to…”
Get full text

Degrade to stay healthy-Proteolytic interplay during inflammation by Münz, Christian

“…Proteasomes and autophagy constitute the 2 main proteolytic machineries for cytoplasmic content. A new study in PLOS Biology now demonstrates that autophagy…”
Get full text

Immune checkpoints in T cells during oncogenic γ‐herpesvirus infections by Münz, Christian

“…Epstein–Barr virus (EBV) and Kaposi sarcoma‐associated herpesvirus (KSHV) are two persistent oncogenic γ‐herpesviruses with an exclusive tropism for humans…”
Get full text

Natural killer cell responses to human oncogenic γ-herpesvirus infections by Münz, Christian

“…The two γ-herpesviruses Epstein Barr virus (EBV) and Kaposi sarcoma associated herpesvirus (KSHV) are each associated with more than 1% of all tumors in…”
Get full text

Non-canonical functions of autophagy proteins in immunity and infection by Münz, Christian

“…The molecular machinery of macroautophagy, a catabolic pathway for cytoplasmic constituent degradation in lysosomes, remodels membranes by lipid…”
Get full text

Non-canonical roles of autophagy proteins in endocytosis and exocytosis by Münz, Christian

“…Autophagy, the pathways that degrade cytoplasmic constituents in lysosomes, contribute to most biological processes from aging and neurodegeneration to…”
Get more information

The Autophagic Machinery in Viral Exocytosis by Münz, Christian

“…The discovery of the molecular machinery of autophagy, namely Atg proteins, was awarded with the Nobel prize in physiology and medicine to Yoshinori Ohsumi in…”
Get full text

Autophagy proteins in antigen processing for presentation on MHC molecules by Muenz, Christian

“…Summary Autophagy describes catabolic pathways that deliver cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC)…”
Get full text

Cytotoxicity in Epstein Barr virus specific immune control by Münz, Christian

“…•Persistent oncogenic Epstein Barr virus (EBV) infection is kept in check by cytotoxic lymphocytes.•Primary immunodeficiencies suggest these to primarily be…”
Get full text

The Macroautophagy Machinery in MHC Restricted Antigen Presentation by Münz, Christian

“…Autophagy-related (ATG) gene products regulate macroautophagy, LC3-associated phagocytosis (LAP) and LC3-dependent extracellular vesicle loading and secretion…”
Get full text

Modulation of Epstein-Barr-Virus (EBV)-Associated Cancers by Co-Infections by Münz, Christian

“…The oncogenic and persistent Epstein Barr virus (EBV) is carried by more than 95% of the human adult population. While asymptomatic in most of these, EBV can…”
Get full text

Innate and Adaptive Immunity through Autophagy by Schmid, Dorothee, Münz, Christian

“…The two main proteolytic machineries of eukaryotic cells, lysosomes and proteasomes, receive substrates by different routes. Polyubiquitination targets…”
Get full text

Epstein-Barr Virus-Specific Immune Control by Innate Lymphocytes by Münz, Christian

“…Epstein-Barr virus (EBV) is a potent B cell transforming pathogen in humans. In most persistently EBV-infected individuals, potent cytotoxic lymphocyte…”
Get full text

Immune Escape by Non-coding RNAs of the Epstein Barr Virus by Münz, Christian

“…Epstein Barr virus (EBV) is one of the most successful pathogens of humans, persistently colonizing more than 95% of the adult human population. At the same…”
Get full text

The Macroautophagy Machinery in Endo- and Exocytosis by Münz, Christian

“…Macroautophagy and the autophagy-related gene (Atg) machinery execute during their canonical function cytoplasmic constituent degradation in lysosomes. This…”
Get full text

The Role of Lytic Infection for Lymphomagenesis of Human γ-Herpesviruses by Münz, Christian

“…Epstein Barr virus (EBV) and Kaposi sarcoma associated herpesvirus (KSHV) are two oncogenic human γ-herpesviruses that are each associated with 1-2% of human…”
Get full text

Epstein–Barr virus as a leading cause of multiple sclerosis: mechanisms and implications by Bjornevik, Kjetil, Münz, Christian, Cohen, Jeffrey I., Ascherio, Alberto

“…Epidemiological studies have provided compelling evidence that multiple sclerosis (MS) is a rare complication of infection with the Epstein–Barr virus (EBV), a…”
Get full text