Search Results - "Müsken, Mathias"

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors by Storz, Michael P, Maurer, Christine K, Zimmer, Christina, Wagner, Nathalie, Brengel, Christian, de Jong, Johannes C, Lucas, Simon, Müsken, Mathias, Häussler, Susanne, Steinbach, Anke, Hartmann, Rolf W

“…2-Heptyl-4-hydroxyquinoline (HHQ) and Pseudomonas quinolone signal (PQS) are involved in the regulation of virulence factor production and biofilm formation in…”
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Lamellipodia-like actin networks in cells lacking WAVE regulatory complex by Kage, Frieda, Döring, Hermann, Mietkowska, Magdalena, Schaks, Matthias, Grüner, Franziska, Stahnke, Stephanie, Steffen, Anika, Müsken, Mathias, Stradal, Theresia E. B., Rottner, Klemens

“…ABSTRACT Cell migration frequently involves the formation of lamellipodia induced by Rac GTPases activating WAVE regulatory complex (WRC) to drive Arp2/3…”
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A 96-well-plate-based optical method for the quantitative and qualitative evaluation of Pseudomonas aeruginosa biofilm formation and its application to susceptibility testing by Häussler, Susanne, Müsken, Mathias, Di Fiore, Stefano, Römling, Ute

“…A major reason for bacterial persistence during chronic infections is the survival of bacteria within biofilm structures, which protect cells from…”
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Isolation and characterization of bacteriophages specific to Streptococcus equi subspecies zooepidemicus and evaluation of efficacy ex vivo by Köhne, Martin, Hüsch, Ronja, Tönissen, Anna, Schmidt, Matthias, Müsken, Mathias, Böttcher, Denny, Hirnet, Juliane, Plötz, Madeleine, Kittler, Sophie, Sieme, Harald

“…Streptococcus (S.) equi subspecies (subsp.) zooepidemicus is an important facultative pathogen in horses and can cause severe infections in other species…”
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Genetic determinants of Pseudomonas aeruginosa biofilm establishment by Musken, Mathias, Di Fiore, Stefano, Dotsch, Andreas, Fischer, Rainer, Haussler, Susanne

“…1 Chronic Pseudomonas Infection Research Group, Helmholtz Center for Infection Research, Inhoffenstrasse 7, D-38124 Braunschweig, Germany 2 Institute for…”
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Qipengyuania pacifica sp. nov., a Novel Carotenoid-Producing Marine Bacterium of the Family Erythrobacteraceae, Isolated from Sponge (Demospongiae), and Antimicrobial Potential of Its Crude Extract by Tareen, Sanaullah, Risdian, Chandra, Müsken, Mathias, Wink, Joachim

“…A marine Alphaproteobacterium designated as strain NZ-96T was isolated in February 2021, from a sponge species (Demospongiae) collected in muddy sediments with…”
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Targeting bioenergetics is key to counteracting the drug-tolerant state of biofilm-grown bacteria by Donnert, Monique, Elsheikh, Sarah, Arce-Rodriguez, Alejandro, Pawar, Vinay, Braubach, Peter, Jonigk, Danny, Haverich, Axel, Weiss, Siegfried, Müsken, Mathias, Häussler, Susanne

“…Embedded in an extracellular matrix, biofilm-residing bacteria are protected from diverse physicochemical insults. In accordance, in the human host the general…”
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Alteriqipengyuania abyssalis sp. nov., a Novel Member of the Class Alphaproteobacteria Isolated from Sponge, and Emended Description of the Genus Alteriqipengyuania by Tareen, Sanaullah, Risdian, Chandra, Müsken, Mathias, Wink, Joachim

“…A novel Gram-negative, aerobic, motile, lemon-yellow-colored, and non-spore-forming rod-shaped bacterium designated strain NZ-12BT was isolated in February…”
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Use of Single-Frequency Impedance Spectroscopy to Characterize the Growth Dynamics of Biofilm Formation in Pseudomonas aeruginosa by van Duuren, Jozef B. J. H., Müsken, Mathias, Karge, Bianka, Tomasch, Jürgen, Wittmann, Christoph, Häussler, Susanne, Brönstrup, Mark

“…Impedance spectroscopy has been applied in prokaryotic and eukaryotic cytometry as a label-free method for the investigation of adherent cells. In this paper,…”
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cGAS-Mediated Innate Immunity Spreads Intercellularly through HIV-1 Env-Induced Membrane Fusion Sites by Xu, Shuting, Ducroux, Aurélie, Ponnurangam, Aparna, Vieyres, Gabrielle, Franz, Sergej, Müsken, Mathias, Zillinger, Thomas, Malassa, Angelina, Ewald, Ellen, Hornung, Veit, Barchet, Winfried, Häussler, Susanne, Pietschmann, Thomas, Goffinet, Christine

“…Upon sensing cytoplasmic retroviral DNA in infected cells, cyclic GMP-AMP (cGAMP) synthase (cGAS) produces the cyclic dinucleotide cGAMP, which activates STING…”
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Transcriptome Dynamics of Pseudomonas aeruginosa during Transition from Overlapping To Non-Overlapping Cell Cycles by Alpers, Kathrin, Vatareck, Elisabeth, Gröbe, Lothar, Müsken, Mathias, Scharfe, Maren, Häussler, Susanne, Tomasch, Jürgen

“…Bacteria either duplicate their chromosome once per cell division or a new round of replication is initiated before the cells divide, thus cell cycles overlap…”
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Streptococcus pneumoniae Affects Endothelial Cell Migration in Microfluidic Circulation by Kopenhagen, Anna, Ramming, Isabell, Camp, Belinda, Hammerschmidt, Sven, Fulde, Marcus, Müsken, Mathias, Steinert, Michael, Bergmann, Simone

“…Bloodstream infections caused by induce strong inflammatory and procoagulant cellular responses and affect the endothelial barrier of the vascular system…”
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Screening Privileged Alkyl Guanidinium Motifs under Host-Mimicking Conditions Reveals a Novel Antibiotic with an Unconventional Mode of Action by Schum, Dominik, Elsen, Franziska A. V., Ruddell, Stuart, Schorpp, Kenji, Junca, Howard, Müsken, Mathias, Chen, Shu-Yu, Fiedler, Michaela K., Pickl, Thomas, Pieper, Dietmar H., Hadian, Kamyar, Zacharias, Martin, Sieber, Stephan A.

“…Screening large molecule libraries against pathogenic bacteria is often challenged by a low hit rate due to limited uptake, underrepresentation of antibiotic…”
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Novel colloidal associations of soyasaponins and lipid components (DPPC, cholesterol) as potential adjuvants for vaccines by de Groot, Carolin, Müsken, Mathias, Bleckmann, Maren, Ebensen, Thomas, Guzmán, Carlos A., Müller-Goymann, Christel C.

“…[Display omitted] Soyasaponins from soybean (Glycine max) represent promising new potent adjuvants for vaccine research because of their immunostimulating…”
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Isolation and characterization of the new Streptomyces phages Kamino, Geonosis, Abafar, and Scarif infecting a broad range of host species by Rackow, Bente, Rolland, Clara, Mohnen, Isabelle, Wittmann, Johannes, Müsken, Mathias, Overmann, Jörg, Frunzke, Julia

“…, a multifaceted genus of soil-dwelling bacteria belonging to the phylum , features intricate phage-host interactions shaped by its complex life cycle and the…”
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A Photoconvertible Reporter System for Bacterial Metabolic Activity Reveals That Staphylococcus aureus Enters a Dormant-Like State to Persist within Macrophages by Lang, Julia C., Seiß, Elena A., Moldovan, Adriana, Müsken, Mathias, Sauerwein, Till, Fraunholz, Martin, Müller, Andreas J., Goldmann, Oliver, Medina, Eva

“…Staphylococcus aureus is a leading cause of difficult-to-treat infections. The capacity of S. aureus to survive and persist within phagocytic cells is an…”
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Pacificimonas pallium sp. nov., an Isolated Bacterium from the Mantle of Pacific Oyster Crassostrea gigas in Germany, and Prediction of One-Carbon Metabolism by Pira, Hani, Risdian, Chandra, Müsken, Mathias, Schupp, Peter J., Wink, Joachim

“…A yellow bacterium from marine agar, strain WHA3T, was isolated from the mantel of the Pacific oysters Crassostrea gigas in the Wilhelmshaven Sea in northern…”
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Cortactin-dependent control of Par1b-regulated epithelial cell polarity in Helicobacter infection by Sharafutdinov, Irshad, Harrer, Aileen, Müsken, Mathias, Rottner, Klemens, Sticht, Heinrich, Täger, Christian, Naumann, Michael, Tegtmeyer, Nicole, Backert, Steffen

“…Cell polarity is crucial for gastric mucosal barrier integrity and mainly regulated by polarity-regulating kinase partitioning-defective 1b (Par1b). During…”
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Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype by Thöming, Janne G., Tomasch, Jürgen, Preusse, Matthias, Koska, Michal, Grahl, Nora, Pohl, Sarah, Willger, Sven D., Kaever, Volkhard, Müsken, Mathias, Häussler, Susanne

“…Studying parallel evolution of similar traits in independent within-species lineages provides an opportunity to address evolutionary predictability of…”
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Inhibitory Effects of the Fungal Pigment Rubiginosin C on Hyphal and Biofilm Formation in Candida albicans and Candida auris by Zeng, Haoxuan, Stadler, Marc, Abraham, Wolf-Rainer, Müsken, Mathias, Schrey, Hedda

“…The two fungal human pathogens, and , possess a variety of virulence mechanisms. Among them are the formation of biofilms to protect yeast against harsh…”
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