Search Results - "Müller, F. U."

CREB critically regulates action potential shape and duration in the adult mouse ventricle by Schulte, J S, Seidl, M D, Nunes, F, Freese, C, Schneider, M, Schmitz, W, Müller, F U

“…The cAMP response element binding protein (CREB) belongs to the CREB/cAMP response element binding modulator/activating transcription factor 1 family of…”
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Gene construction, expression and functional testing of an inotropic peptide from the venom of the black scorpion Hottentotta judaicus by Tekook, M.A., Fabritz, L., Kirchhof, P., König, S., Müller, F.U., Schmitz, W., Tal, T., Zlotkin, E., Kirchhefer, U.

“…Anti-insect depressant toxins represent a subfamily of scorpion venom-derived β-toxins that are polypeptides composed of 61–65 amino acid residues stabilized…”
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Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21 by Müller, Ulrich F., Lambert, Laurence, Göringer, H. Ulrich

“…RNA editing within the mitochondria of African trypanosomes is characterized by the insertion and deletion of uridylate residues into otherwise incomplete…”
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CREM-transgene mice: An animal model of atrial fibrillation and thrombogenesis by Bukowska, A., Felgendreher, M., Scholz, B., Wolke, C., Schulte, J.S., Fehrmann, E., Wardelmann, E., Seidl, M.D., Lendeckel, U., Himmler, K., Gardemann, A., Goette, A., Müller, F.U.

“…The molecular pathomechanisms underlying atrial thrombogenesis are multifactorial and still require detailed investigations. Transgenic mice with…”
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Cardiac expression of the CREM repressor isoform CREM-IbΔC-X in mice leads to arrhythmogenic alterations in ventricular cardiomyocytes by Schulte, J. S., Fehrmann, E., Tekook, M. A., Kranick, D., Fels, B., Li, N., Wehrens, X. H. T., Heinick, A., Seidl, M. D., Schmitz, W., Müller, F. U.

“…Chronic β-adrenergic stimulation is regarded as a pivotal step in the progression of heart failure which is associated with a high risk for arrhythmia. The…”
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Triggered activity in atrial myocytes is influenced by Na+/Ca2+ exchanger activity in genetically altered mice by Bögeholz, N., Pauls, P., Kaese, S., Schulte, J.S., Lemoine, M.D., Dechering, D.G., Frommeyer, G., Goldhaber, J.I., Seidl, M.D., Kirchhefer, U., Eckardt, L., Müller, F.U., Pott, C.

“…In atrial fibrillation, increased function of the Na+/Ca2+-exchanger (NCX) is one among several electrical remodeling mechanisms. Using the patch-clamp- and…”
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Re-creating an RNA world by Mueller, U F

“…The RNA world hypothesis states that life originated via a system based on RNA genomes and RNA catalysts. Researchers have been trying to develop such a system…”
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Fibre-related nitric oxide synthase (NOS) in Duchenne muscular dystrophy by Punkt, K, Schering, S, Fritzsche, M, Asmussen, G, Minin, E A, Samoilova, V E, Müller, F-U, Schmitz, W, Hasselblatt, M, Paulus, W, Müller-Werdan, U, Slezak, J, Koehler, G, Boecker, W, Buchwalow, I B

“…Nitric oxide (NO) mediates fundamental physiological actions on skeletal muscle. The loss of NO synthase (NOS) from the sarcolemma was assumed to be associated…”
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Effects of endotoxin on human myocardial contractility involvement of nitric oxide and peroxynitrite by Flesch, Markus, Kilter, Heiko, Cremers, Bodo, Laufs, Ulrich, Südkamp, Michael, Ortmann, Monika, Müller, Frank U, Böhm, Michael

“…OBJECTIVES This study examined the effects of endotoxin on cardiac contractility in human myocardium. BACKGROUND In animal myocardium, endotoxin and cytokine…”
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Transcription factor cAMP response element modulator (Crem) restrains Pdgf-dependent proliferation of vascular smooth muscle cells in mice by Seidl, M. D., Steingräber, A. K., Wolf, C. T., Sur, T. M. H., Hildebrandt, I., Witten, A., Stoll, M., Fischer, J. W., Schmitz, W., Müller, F. U.

“…Transcription factors of the cAMP response element-binding protein (Creb)/cAMP response element modulator (Crem) family were linked to the switch from a…”
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Transcription factor AP-2α triggers apoptosis in cardiac myocytes by Müller, F U, Loser, K, Kleideiter, U, Neumann, J, von Wallbrunn, C, Dobner, T, Scheld, H-H, Bantel, H, Engels, I H, Schulze-Osthoff, K, Schmitz, W

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Protein phosphatase activity is increased in a rat model of long-term beta-adrenergic stimulation by Bokník, P, Fockenbrock, M, Herzig, S, Knapp, J, Linck, B, Lüss, H, Müller, F U, Müller, T, Schmitz, W, Schröder, F, Neumann, J

“…We tested the hypothesis that altered phosphorylation of Ca2+ regulatory proteins contributes to contractile anomalies in cardiac hypertrophy. Cardiac…”
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Regional expression of phospholamban in the human heart by BOKNIK, P, UNKEL, C, VAHLENSIECK, U, ZIMMERMANN, N, JONES, L. R, NEUMANN, J, KIRCHHEFER, U, KLEIDEITER, U, KLEIN-WIELE, O, KNAPP, J, LINCK, B, LÜSS, H, MÜLLER, F. U, SCHMITZ, W

“…Several independent lines of evidence indicate that phospholamban (PLB) expression correlates positively with depression of force of contraction and duration…”
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The role of transcription factors in the formation of an arrhythmogenic substrate in congestive human heart failure by Schulte, J S, Seidl, M D, Müller, F U

“…Human congestive heart failure is accompanied by structural and electrical alterations leading to the development of an arrhythmogenic substrate. This…”
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Expression of calcium regulatory proteins in short-term hibernation and stunning in the in situ porcine heart by LÜSS, H, BOKNIK, P, HEUSCH, G, MÜLLER, F. U, NEUMANN, J, SCHMITZ, W, SCHULZ, R

“…Myocardial hibernation and stunning are characterised by a reversible contractile dysfunction during and after ischaemia, respectively. Calcium homeostasis…”
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The heat exchanger network design as a paradigm of technology integration by Tantimuratha, L, Kokossis, A.C, Müller, F.U

“…The work presents evidence from experiments that attempt to combine optimisation technologies of different qualities and advantages. The evidence is…”
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Effects of cantharidin on force of contraction and phosphatase activity in nonfailing and failing human hearts by Linck, Bettina, Boknik, Peter, Knapp, Jörg, Müller, Frank U., Neumann, Joachim, Schmitz, Wilhelm, Vahlensieck, Ute

“…1 The effect of the phosphatase inhibitor, cantharidin (3–300 μm) on force of contraction was studied in isolated electrically driven right ventricular…”
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Inotropic Effects of Diadenosine Tetraphosphate in Isolated Canine Cardiac Preparations by Neumann, J, Meissner, A, Bokník, P, Gombosová, I, Knapp, J, Lüss, H, Müller, F-U, Schlüter, H, Zidek, W, Rolf, N, Van Aken, H, Vahlensieck, U, Schmitz, W

“…We studied the effects of diadenosine tetraphosphate (AP4A) on the force of contraction in canine preparations. The force of contraction was measured in…”
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Molecular aspects of adrenergic signal transduction in cardiac failure by HAJJAR, R. J, MÜLLER, F. U, SCHMITZ, W, SCHNABEL, P, BÖHM, M

“…Abnormal beta-adrenergic signal transduction and intracellular Ca2+ handling appear to be a major cause of systolic and diastolic dysfunction in humans with…”
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Receptor mechanisms involved in the 5‐HT‐induced inotropic action in the rat isolated atrium by Läer, Stephanie, Remmers, Freerk, Scholz, Hasso, Stein, Birgitt, Ulrich Müller, Frank, Neumann, Joachim

“…1 The effects of 5‐hydroxytryptamine (5‐HT) in rat cardiac preparations were studied. 5‐HT up to 10 μM failed to affect contractility in papillary muscles…”
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