Search Results - "Muñoz‐Antonia, Teresita"
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Racial and Ethnic Differences in the Epidemiology and Genomics of Lung Cancer
Published in Cancer control (01-10-2016)“…Lung cancer is the most common cancer in the world. In addition to the geographical and sex-specific differences in the incidence, mortality, and survival…”
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Characterization of epidermal growth factor receptor (EGFR) P848L, an unusual EGFR variant present in lung cancer patients, in a murine Ba/F3 model
Published in FEBS open bio (01-10-2019)“…Lung cancer patients with mutations in epidermal growth factor receptor (EGFR) benefit from treatments targeting tyrosine kinase inhibitors (TKIs). However,…”
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A community‐based lung cancer rapid tissue donation protocol provides high‐quality drug‐resistant specimens for proteogenomic analyses
Published in Cancer medicine (Malden, MA) (01-01-2020)“…Background For the advancement of cancer research, the collection of tissue specimens from drug‐resistant tumors after targeted therapy is crucial. Although…”
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Suppression of Rho B Expression in Invasive Carcinoma from Head and Neck Cancer Patients
Published in Clinical cancer research (01-07-2002)“…Purpose: In contrast to Ras small GTPases, which contribute to human malignancy when overexpressed or constitutively activated, convincing evidence for the…”
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Trim28 contributes to EMT via regulation of E-cadherin and N-cadherin in lung cancer cell lines
Published in PloS one (01-07-2014)“…In previous work, we demonstrated that transcription factor Trim28 (Tripartite motif containing 28) plays a tumor-suppressor role in early-staged…”
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ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer
Published in PloS one (20-01-2016)“…Epithelial-mesenchymal transition (EMT) is one mechanism of acquired resistance to inhibitors of the epidermal growth factor receptor-tyrosine kinases…”
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Differences in Smad4 Expression in Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Squamous Cell Carcinoma
Published in Clinical cancer research (01-05-2005)“…The SMADs are a group of interrelated proteins that mediate transforming growth factor β (TGF-β) signaling. Upon TGF-β binding the TGF-β type I receptor…”
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Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarker
Published in PloS one (19-11-2018)“…Prediction of lung cancer metastasis relies on post-resection assessment of tumor histology, which is a severe limitation since only a minority of lung cancer…”
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Regulation of the human transforming growth factor β type II receptor gene promoter by novel Sp1 sites
Published in Oncogene (18-10-2001)“…The transforming growth factor-beta (TGF beta) type II receptor (T beta R-II) is responsible for transducing the growth inhibitory signals of TGF beta. The T…”
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Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer
Published in PloS one (11-12-2014)“…Lung cancer is the second most common cancer and the leading cause of cancer-related deaths. Despite recent advances in the development of targeted therapies,…”
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Lung cancer mutations and use of targeted agents in Hispanics
Published in Reviews on recent clinical trials (01-01-2014)“…Hispanic/Latinos (H/L) are expected to grow to over 24% of the USA population by 2050 and lung cancer is the number one cause of cancer death among H/L men…”
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Expression of TGFβ type‐II receptor in association with markers of proliferation and apoptosis in premalignant lung lesions
Published in Cancer (01-10-2007)“…BACKGROUND. Analysis of the early molecular abnormalities that play an oncogenic role in the progression of pulmonary neoplasia may lead to the identification…”
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Defective Transforming Growth Factor β Signaling Pathway in Head and Neck Squamous Cell Carcinoma as Evidenced by the Lack of Expression of Activated Smad2
Published in Clinical cancer research (01-06-2001)“…Purpose: Transforming growth factor β (TGF-β) regulates cell growth and differentiation, in normal squamous epithelium, via specific TGF-β receptors and…”
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Don't neglect cultural diversity in oncology care
Published in Journal of the National Comprehensive Cancer Network (01-05-2014)“…The growing Hispanic population in the United States mandates the need for oncology providers to become more familiar with disease patterns and cultural belief…”
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Worse Clinical and Survival Outcomes in Breast Cancer Patients Living in Puerto Rico Compared to Hispanics, Non-Hispanic Blacks, and Non-Hispanic Whites from Florida
Published in Journal of racial and ethnic health disparities (14-11-2024)“…Herein, we report the characterization of four cohorts of breast cancer patients including (1) non-Hispanic Whites in Florida, (2) non-Hispanic Blacks in…”
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Expression of Transforming Growth Factor β Type II Receptors in Head and Neck Squamous Cell Carcinoma
Published in Clinical cancer research (01-06-1999)“…Transforming growth factor (TGF)-β is a potent regulator of growth and differentiation in normal squamous epithelium. TGF-β exerts its antiproliferative effect…”
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Patient, caregiver and physician perspectives on participating in a thoracic rapid tissue donation program
Published in Patient education and counseling (01-04-2018)“…•Rapid Tissue Donation (RTD) recruitment poses several ethical challenges.•Exploring patient and family perspectives is critical for successful…”
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Improving Awareness of Cancer Clinical Trials Among Hispanic Patients and Families: Audience Segmentation Decisions for a Media Intervention
Published in Journal of health communication (01-09-2013)“…Clinical trials hold great promise for cancer treatment; yet, Hispanic cancer patients have low rates of clinical trial participation. Lack of awareness and…”
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Abstract 1050: Alvespimycin (17-DMAG) blocks TGFβ-induced EMT and migration in A549 lung cancer cells
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Background: Transforming Growth Factor β (TGFβ) can induce Epithelial-to-Messenchymal Transition (EMT) in Non-Small Cell Lung Cancer (NSCLC) leading to…”
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Altruism in terminal cancer patients and rapid tissue donation program: does the theory apply?
Published in Medicine, health care, and philosophy (01-11-2013)“…Rapid tissue donation (RTD) is an advancing oncology research procedure for collecting tumors, metastases, and unaffected tissue 2–6 h after death. Researchers…”
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