Search Results - "Muñoz, Ivan M."

Quantification and enantiomeric distribution of clenbuterol in several bovine tissues using UHPLC–tandem mass spectrometry: Evaluation of a risk factor associated with meat contamination by Velasco‐Bejarano, Benjamín, Espinoza‐Muñoz, Ivan M., Álvarez‐Sánchez, Alan, Gómez‐Tagle, Anuar, Velasco‐Carrillo, Ricardo, Bautista, Jahir, Rodríguez, Leonardo

“…Clenbuterol (Clb) (4‐amino‐α‐[(tert‐butylamine) methyl]‐3,5‐dichlorobenzyl alcohol) is a sympathomimetic agent that exhibits β2‐agonist activity. It is applied…”
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RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health by Feeney, Laura, Muñoz, Ivan M., Lachaud, Christophe, Toth, Rachel, Appleton, Paul L., Schindler, Detlev, Rouse, John

“…Defects in the repair of DNA interstrand crosslinks (ICLs) are associated with the genome instability syndrome Fanconi anemia (FA). Here we report that cells…”
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Phosphoproteomic screening identifies physiological substrates of the CDKL5 kinase by Muñoz, Ivan M, Morgan, Michael E, Peltier, Julien, Weiland, Florian, Gregorczyk, Mateusz, Brown, Fiona CM, Macartney, Thomas, Toth, Rachel, Trost, Matthias, Rouse, John

“…Mutations in the gene encoding the protein kinase CDKL5 cause a debilitating neurodevelopmental disease termed CDKL5 disorder. The impact of these mutations on…”
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Coordination of Structure-Specific Nucleases by Human SLX4/BTBD12 Is Required for DNA Repair by Muñoz, Ivan M., Hain, Karolina, Déclais, Anne-Cécile, Gardiner, Mary, Toh, Geraldine W., Sanchez-Pulido, Luis, Heuckmann, Johannes M., Toth, Rachel, Macartney, Thomas, Eppink, Berina, Kanaar, Roland, Ponting, Chris P., Lilley, David M.J., Rouse, John

“…Budding yeast Slx4 interacts with the structure-specific endonuclease Slx1 to ensure completion of ribosomal DNA replication. Slx4 also interacts with the…”
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Control of histone methylation and genome stability by PTIP by Muñoz, Ivan M, Rouse, John

“…PTIP regulates gene transcription by controlling the methylation of histone H3, and also has important roles in cellular responses to DNA damage or to…”
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Family with Sequence Similarity 60A (FAM60A) Protein Is a Cell Cycle-fluctuating Regulator of the SIN3-HDAC1 Histone Deacetylase Complex by Muñoz, Ivan M., MacArtney, Thomas, Sanchez-Pulido, Luis, Ponting, Chris P., Rocha, Sonia, Rouse, John

“…The SIN3A-HDAC complex deacetylates histones thereby repressing gene transcription. Here we describe family with sequence similarity 60A (FAM60A), a cell…”
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Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage by Munoz, Ivan M, Jowsey, Paul A, Toth, Rachel, Rouse, John

“…Human (h)PTIP plays important but poorly understood roles in cellular responses to DNA damage. hPTIP interacts with 53BP1 tumour suppressor but only when 53BP1…”
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Endogenous DNA 3′ Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease by Álvarez-Quilón, Alejandro, Wojtaszek, Jessica L., Mathieu, Marie-Claude, Patel, Tejas, Appel, C. Denise, Hustedt, Nicole, Rossi, Silvia Emma, Wallace, Bret D., Setiaputra, Dheva, Adam, Salomé, Ohashi, Yota, Melo, Henrique, Cho, Tiffany, Gervais, Christian, Muñoz, Ivan M., Grazzini, Eric, Young, Jordan T.F., Rouse, John, Zinda, Michael, Williams, R. Scott, Durocher, Daniel

“…The APEX2 gene encodes APE2, a nuclease related to APE1, the apurinic/apyrimidinic endonuclease acting in base excision repair. Loss of APE2 is lethal in cells…”
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Improved genome editing in human cell lines using the CRISPR method by Munoz, Ivan M, Szyniarowski, Piotr, Toth, Rachel, Rouse, John, Lachaud, Christophe

“…The Cas9/CRISPR system has become a popular choice for genome editing. In this system, binding of a single guide (sg) RNA to a cognate genomic sequence enables…”
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PTIP/Swift is required for efficient PCNA ubiquitination in response to DNA damage by Göhler, Thomas, Munoz, Ivan M., Rouse, John, Blow, J. Julian

“…Monoubiquitination of proliferating cell nuclear antigen (PCNA) enables translesion synthesis (TLS) by specialized DNA polymerases to replicate past damaged…”
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Phosphoproteomic screening identifies physiological substrates of the CDKL 5 kinase by Muñoz, Ivan M, Morgan, Michael E, Peltier, Julien, Weiland, Florian, Gregorczyk, Mateusz, Brown, Fiona CM, Macartney, Thomas, Toth, Rachel, Trost, Matthias, Rouse, John

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Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage by Munoz, Ivan M., Jowsey, Paul A., Toth, Rachel, Rouse, John

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Corrigendum: Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage by Munoz, Ivan M, Jowsey, Paul A, Toth, Rachel, Rouse, John

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Improved Genome Editing in Human Cell Lines Using the CRISPR Method: e109752 by Munoz, Ivan M, Szyniarowski, Piotr, Toth, Rachel, Rouse, John, Lachaud, Christophe

“…The Cas9/CRISPR system has become a popular choice for genome editing. In this system, binding of a single guide (sg) RNA to a cognate genomic sequence enables…”
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