Search Results - "Mu, Zepeng"
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Haplotype-resolved diverse human genomes and integrated analysis of structural variation
Published in Science (American Association for the Advancement of Science) (02-04-2021)“…Long-read and strand-specific sequencing technologies together facilitate the de novo assembly of high-quality haplotype-resolved human genomes without…”
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2
Alternative polyadenylation mediates genetic regulation of gene expression
Published in eLife (25-06-2020)“…Little is known about co-transcriptional or post-transcriptional regulatory mechanisms linking noncoding variation to variation in organismal traits. To begin…”
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The impact of cell type and context-dependent regulatory variants on human immune traits
Published in Genome Biology (29-04-2021)“…The vast majority of trait-associated variants identified using genome-wide association studies (GWAS) are noncoding, and therefore assumed to impact gene…”
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4
Mirabegron displays anticancer effects by globally browning adipose tissues
Published in Nature communications (22-11-2023)“…Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion, and…”
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Progesterone levels associated with proteinuria in male diabetes mellitus patients: A cross‐sectional retrospective study
Published in Journal of diabetes investigation (01-05-2023)“…ABSTRACT Introduction The relationship between progesterone (P) and diabetic nephropathy (DKD) is unclear. Herein, we investigated the relationship between…”
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Letter 2 regarding "Assessing the performance of ChatGPT in answering questions regarding cirrhosis and hepatocellular carcinoma"
Published in Clinical and molecular hepatology (01-01-2024)“…[...]for patients diagnosed with SLD, education plays a pivotal role in understanding, managing, and possibly reversing their condition. In our evolving…”
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A genetically engineered Escherichia coli that senses and degrades tetracycline antibiotic residue
Published in Synthetic and systems biotechnology (01-09-2018)“…Due to the abuse of antibiotics, antibiotic residues can be detected in both natural environment and various industrial products, posing threat to the…”
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CircRNA_103948 inhibits autophagy in colorectal cancer in a ceRNA manner
Published in Annals of the New York Academy of Sciences (01-11-2021)“…Circular RNA (circRNA) is implicated in many types of cancer; however, the expression and role of circRNAs in colorectal cancer (CRC) remains poorly…”
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Retracted: CircRNA_103948 inhibits autophagy in colorectal cancer in a ceRNA manner
Published in Annals of the New York Academy of Sciences (01-11-2021)“…Abstract Circular RNA (circRNA) is implicated in many types of cancer; however, the expression and role of circRNAs in colorectal cancer (CRC) remains poorly…”
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Shaping immunity: The influence of natural selection on population immune diversity
Published in Immunological reviews (01-05-2024)“…Summary Humans exhibit considerable variability in their immune responses to the same immune challenges. Such variation is widespread and affects individual…”
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A multi-tissue, splicing-based joint transcriptome-wide association study identifies susceptibility genes for breast cancer
Published in American journal of human genetics (06-06-2024)“…Splicing-based transcriptome-wide association studies (splicing-TWASs) of breast cancer have the potential to identify susceptibility genes. However, existing…”
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Alignment of single-cell RNA-seq samples without overcorrection using kernel density matching
Published in Genome research (01-04-2021)“…Single-cell RNA sequencing (scRNA-seq) technology is poised to replace bulk cell RNA sequencing for many biological and medical applications as it allows users…”
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Epigenetic variation impacts individual differences in the transcriptional response to influenza infection
Published in Nature genetics (01-03-2024)“…Humans display remarkable interindividual variation in their immune response to identical challenges. Yet, our understanding of the genetic and epigenetic…”
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Predictors of poor response to urate-lowering therapy in patients with gout and hyperuricemia: a post-hoc analysis of a multicenter randomized trial
Published in Clinical rheumatology (01-12-2019)“…Introduction Clinical guidelines have recommended a target of serum uric acid (SUA) level below 6.0 mg/dL for the urate-lowering therapy (ULT) of gout…”
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Blood glucose fluctuations detected by continuous glucose monitoring system in gout patients with normal glucose tolerance and the effect of urate‐lowering therapy
Published in International journal of rheumatic diseases (01-08-2020)“…Aim The aim of this study was to investigate whether there are blood glucose fluctuations in gout patients with hyperuricemia and normal glucose tolerance, and…”
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Clinical and Genome-Wide Analysis of Serum Platinum Levels after Cisplatin-Based Chemotherapy
Published in Clinical cancer research (01-10-2019)“…Serum platinum is measurable for years after completion of cisplatin-based chemotherapy (CBC). We report the largest investigation of serum platinum levels to…”
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Abstract 3904: Pharmacokinetic modeling of serum platinum reveals extent of long-term exposure and associated comorbidities after cisplatin treatment
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Platinum is detectable in the plasma years after completion of cisplatin treatment. Although it has been hypothesized that circulating platinum…”
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Pharmacokinetic (PK) modeling of serum platinum to reveal extent of long-term exposure and associated comorbidities after cisplatin treatment
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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