Search Results - "Mu, Wenli"

Examining Chronic Inflammation, Immune Metabolism, and T Cell Dysfunction in HIV Infection by Mu, Wenli, Patankar, Vaibhavi, Kitchen, Scott, Zhen, Anjie

“…Chronic Human Immunodeficiency Virus (HIV) infection remains a significant challenge to global public health. Despite advances in antiretroviral therapy (ART),…”
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FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling by Zong, Shuai, Jiao, Yulian, Liu, Xin, Mu, Wenli, Yuan, Xiaotian, Qu, Yunyun, Xia, Yu, Liu, Shuang, Sun, Huanxin, Wang, Laicheng, Cui, Bin, Liu, Xiaowen, Li, Ping, Zhao, Yueran

“…FKBP4 belongs to the family of immunophilins, which serve as a regulator for steroid receptor activity. Thus, FKBP4 has been recognized to play a critical role…”
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The Role of Macrophage Efferocytosis in the Pathogenesis of Apical Periodontitis by Guan, Xiaoyue, Wang, Yuting, Li, Wenlan, Mu, Wenli, Tang, Yifei, Wang, Mingfei, Seyam, Abdelrahman, Yang, Yao, Pan, Lifei, Hou, Tiezhou

“…Macrophages (Mφs) play a crucial role in the homeostasis of the periapical immune micro-environment caused by bacterial infection. Mφ efferocytosis has been…”
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Engineering CAR T Cells to Target the HIV Reservoir by Mu, Wenli, Carrillo, Mayra A, Kitchen, Scott G

“…The HIV reservoir remains to be a difficult barrier to overcome in order to achieve a therapeutic cure for HIV. Several strategies have been developed to purge…”
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Robust CAR-T memory formation and function via hematopoietic stem cell delivery by Zhen, Anjie, Carrillo, Mayra A, Mu, Wenli, Rezek, Valerie, Martin, Heather, Hamid, Philip, Chen, Irvin S Y, Yang, Otto O, Zack, Jerome A, Kitchen, Scott G

“…Due to the durability and persistence of reservoirs of HIV-1-infected cells, combination antiretroviral therapy (ART) is insufficient in eradicating infection…”
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Targeting autophagy to treat HIV immune dysfunction by Mu, Wenli, Martin, Heather, Zhen, Anjie

“…Chronic immune activation and inflammation are hallmarks of Human Immunodeficiency Virus-1 (HIV-1) pathogenesis. Therefore, approaches to safely reduce…”
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Cannabidiol modulates expression of type I IFN response genes and HIV infection in macrophages by Tomer, Shallu, Mu, Wenli, Suryawanshi, Gajendra, Ng, Hwee, Wang, Li, Wennerberg, Wally, Rezek, Valerie, Martin, Heather, Chen, Irvin, Kitchen, Scott, Zhen, Anjie

“…Cannabis ( ) is a widely used drug in the United States and the frequency of cannabis use is particularly high among people living with HIV (PLWH). One key…”
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Dexamethasone Sensitizes Acute Monocytic Leukemia Cells to Ara-C by Upregulating FKBP51 by Sun, Huanxin, Liu, Xiaowen, Wang, Laicheng, Cui, Bin, Mu, Wenli, Xia, Yu, Liu, Shuang, Liu, Xin, Jiao, Yulian, Zhao, Yueran

“…In this study, we demonstrated that the expression of FK506 binding protein 51 (FKBP51) is upregulated in acute monocytic leukemia (AML-M5) cells by…”
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Correction: Robust CAR-T memory formation and function via hematopoietic stem cell delivery by Zhen, Anjie, Carrillo, Mayra A, Mu, Wenli, Rezek, Valerie, Martin, Heather, Hamid, Philip, Chen, Irvin S. Y, Yang, Otto O, Zack, Jerome A, Kitchen, Scott G

“…[This corrects the article DOI: 10.1371/journal.ppat.1009404.]…”
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Capturing 3D Chromatin Maps of Human Primary Monocytes: Insights From High-Resolution Hi-C by Xia, Yu, Liu, Xiaowen, Mu, Wenli, Ma, Chunyan, Wang, Laicheng, Jiao, Yulian, Cui, Bin, Hu, Shengnan, Gao, Ying, Liu, Tao, Sun, Huanxin, Zong, Shuai, Liu, Xin, Zhao, Yueran

“…Although the variation in chromatin architecture during adaptive immune responses has been thoroughly investigated, the 3D landscape of innate immunity is…”
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A novel rapid and reproducible flow cytometric method for optimization of transfection efficiency in cells by Homann, Stefanie, Hofmann, Christian, Gorin, Aleksandr M, Nguyen, Huy Cong Xuan, Huynh, Diana, Hamid, Phillip, Maithel, Neil, Yacoubian, Vahe, Mu, Wenli, Kossyvakis, Athanasios, Sen Roy, Shubhendu, Yang, Otto Orlean, Kelesidis, Theodoros

“…Transfection is one of the most frequently used techniques in molecular biology that is also applicable for gene therapy studies in humans. One of the biggest…”
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Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo by Mu, Wenli, Rezek, Valerie, Martin, Heather, Carrillo, Mayra A, Tomer, Shallu, Hamid, Philip, Lizarraga, Miguel A, Tibbe, Tristan D, Yang, Otto O, Jamieson, Beth D, Kitchen, Scott G, Zhen, Anjie

“…A hallmark of HIV-1 infection is chronic inflammation, even in patients treated with antiretroviral therapy (ART). Chronic inflammation drives HIV-1…”
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Non-integrating lentiviral vectors based on the minimal S/MAR sequence retain transgene expression in dividing cells by Xu, Zhen, Chen, Feng, Zhang, Lingling, Lu, Jing, Xu, Peng, Liu, Guang, Xie, Xuemin, Mu, Wenli, Wang, Yajun, Liu, Depei

“…Safe and efficient gene transfer systems are the basis of gene therapy applications. Non-integrating lentiviral （NIL） vectors are among the most promising…”
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Overexpression of a dominant-negative mutant of SIRT1 in mouse heart causes cardiomyocyte apoptosis and early-onset heart failure by Mu, WenLi, Zhang, QingJun, Tang, XiaoQiang, Fu, WenYan, Zheng, Wei, Lu, YunBiao, Li, HongLiang, Wei, YuSheng, Li, Li, She, ZhiGang, Chen, HouZao, Liu, DePei

“…SIRT1, a mammalian ortholog of yeast silent information regulator 2 （Sir2）, is an NAD＋-dependent protein deacetylase that plays a critical role in the…”
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A Flow Cytometric Method to Determine Transfection Efficiency by Mu, Wenli, Homann, Stefanie, Hofmann, Christian, Gorin, Alexandr, Huynh, Diana, Yang, Otto Orlean, Kelesidis, Theodoros

“…Mammalian cell transfection is a powerful technique commonly used in molecular biology to express exogenous DNA or RNA in cells and study gene and protein…”
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Effects of L1-ORF2 fragments on green fluorescent protein gene expression by Wang, Xiu-Fang, Jin, Xia, Wang, Xiaoyan, Liu, Jing, Feng, Jingjing, Yang, Qinqing, Mu, Wenli, Shi, Xiaojuan, Lu, Zhanjun

“…The retrotransposon known as long interspersed nuclear element-1 (L1) is 6 kb long, although most L1s in mammalian and other eukaryotic cells are truncated. L1…”
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Ginsenoside Rb1 ameliorates apical periodontitis via suppressing macrophage pyroptosis by Guan, Xiaoyue, Zhao, Rui, Wang, Yuting, Li, Wenlan, Pan, Lifei, Yang, Yao, Mu, Wenli, Hou, Tie Zhou

“…The objectives of current study were to investigate the role and related mechanism of Ginsenoside Rb1 (GRb1) on regulating apical periodontitis (AP) prognosis…”
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The possible role of Gremlin1 in inflammatory apical periodontitis by Guan, Xiaoyue, Shi, Chen, Wang, Yuting, He, Yani, Li, Yingxue, Yang, Yao, Mu, Wenli, Li, Wenlan, Hou, Tiezhou

“…OBJECTIVEIn this study, we investigated the involvement of Gremlin1 on the pathological process of apical periodontitis and detect the underlying mechanisms…”
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Delineate the effects of cannabidiol on type 1 IFN mediated inflammation during HIV infection by Tomer, Shallu, Mu, Wenli, Ng, Hwee, Wang, Li, Wennerberg, Wally, Razek, Valerie, Martin, Heather, Zhen, Anjie, Kitchen, Scott

“…Abstract Methods THP-1 and HMC3 cells were exposed to CBD/vehicle with and without stimulation with 2’3'-cGAMP (cGAMP), LPS, or PMA/ionomycin. qPCR was carried…”
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Induction of Autophagy reduces IFN-I mediated Inflammation and restores anti-HIV-1 T Cell response in vivo by Zhen, Anjie, Mu, Wenli, Rezek, Valerie, Martin, Heather, Carrillo, Mayra, Hamid, Philip, Lizarraga, Miguel, Yang, Otto, Jamieson, Beth, Kitchen, Scott

“…Abstract A hallmark of HIV-1 infection is chronic inflammation. Chronic immune activation drives the pathogenesis of HIV-1 infection, leading to loss of CD4+ T…”
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