Search Results - "Mu, Chenglong"
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Dynamic PGAM5 multimers dephosphorylate BCL-xL or FUNDC1 to regulate mitochondrial and cellular fate
Published in Cell death and differentiation (01-03-2020)“…Mitochondria are highly dynamic organelles and respond to stress by changing their fission-fusion cycle, undergoing mitophagy, or releasing apoptotic proteins…”
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2
Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy
Published in Cell research (01-02-2017)“…Autophagy requires diverse membrane sources and involves membrane trafficking of mATG9, the only membrane protein in the ATG family. However, the molecular…”
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3
The SIAH2-NRF1 axis spatially regulates tumor microenvironment remodeling for tumor progression
Published in Nature communications (04-03-2019)“…The interactions between tumor cells with their microenvironments, including hypoxia, acidosis and immune cells, lead to the tumor heterogeneity which promotes…”
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4
Zyxin-Siah2–Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways
Published in Nature communications (31-03-2016)“…The evolutionarily conserved Hippo pathway is a regulator that controls organ size, cell growth and tissue homeostasis. Upstream signals of the Hippo pathway…”
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Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy
Published in Autophagy (01-01-2015)“…Mitochondria serve as membrane sources and signaling platforms for regulating autophagy. Accumulating evidence has also shown that damaged mitochondria are…”
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Receptor-mediated mitophagy regulates EPO production and protects against renal anemia
Published in eLife (04-05-2021)“…Erythropoietin (EPO) drives erythropoiesis and is secreted mainly by the kidney upon hypoxic or anemic stress. The paucity of EPO production in renal…”
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Prostate cancer cells synergistically defend against CD8+ T cells by secreting exosomal PD‐L1
Published in Cancer medicine (Malden, MA) (01-08-2023)“…Background Metastatic castration‐resistant prostate cancer (mCRPC) remains fatal and incurable, despite a variety of treatments that can delay disease…”
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8
Hypoxia-induced proteasomal degradation of DBC1 by SIAH2 in breast cancer progression
Published in eLife (01-08-2022)“…DBC1 has been characterized as a key regulator of physiological and pathophysiological activities, such as DNA damage, senescence, and tumorigenesis. However,…”
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9
High-fat diet promotes prostate cancer metastasis via RPS27
Published in Cancer & metabolism (16-02-2024)“…Metastasis is the leading cause of death among prostate cancer (PCa) patients. Obesity is associated with both PCa-specific and all-cause mortality. High-fat…”
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10
MoS2@ZIF-8 doped waterborne polyurethane membranes with water vapor permeable, lubricating, and antibacterial properties
Published in Progress in organic coatings (01-12-2021)“…In this research, a multi-functional waterborne polyurethane (WPU) membrane was developed through the in-situ synthesis of molybdenum disulfide/zeolitic…”
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11
Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
Published in Nature cell biology (01-01-2015)“…Wu and colleagues report that under hypoxic conditions the LATS2 kinase is targeted for degradation by the SIAH2 ubiquitin ligase, leading to inhibition of the…”
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12
Pt nanoenzyme decorated yolk-shell nanoplatform as an oxygen generator for enhanced multi-modality imaging-guided phototherapy
Published in Journal of colloid and interface science (15-06-2022)“…Fe3O4@PDA@Pt-PEG-Ce6 nanoplatform have been prepared for multi-mode imaging-guided PDT and PTT tumor therapeutics. [Display omitted] The unsatisfactory…”
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13
Versatile Nanoplatforms with enhanced Photodynamic Therapy: Designs and Applications
Published in Theranostics (01-01-2020)“…As an emerging antitumor strategy, photodynamic therapy (PDT) has attracted intensive attention for the treatment of various malignant tumors owing to its…”
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Journal Article Book Review -
14
Pom Functionalized Ionogels with Tunable Optical, Mechanical, Electrical, and Sensory Properties
Published in Advanced functional materials (01-04-2024)“…Abstract Ionogels, with wide applications in tissue engineering, soft robotics, and flexible iontronic devices, require tunable optical, mechanical, and…”
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Recent advances in graphite carbon nitride-based nanocomposites: structure, antibacterial properties and synergies
Published in Nanoscale advances (30-06-2021)“…Bacterial infections and transmission threaten human health and well-being. Graphite carbon nitride (g-C 3 N 4 ), a promising photocatalytic antibacterial…”
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Fluorinated branched polymer enables Ce6 and IR780 more effective for phototherapy
Published in Nano select (16-07-2021)“…Abstract Phototherapy is gradually becoming a primary technique for treating tumors due to increased efficacy and less side effects. It largely depends on the…”
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17
PAFAH2 suppresses synchronized ferroptosis to ameliorate acute kidney injury
Published in Nature chemical biology (01-07-2024)“…Synchronized ferroptosis contributes to nephron loss in acute kidney injury (AKI). However, the propagation signals and the underlying mechanisms of the…”
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Graphitic Carbon Nitride/Zeolitic Imidazolate Framework‑8 Nanoparticles with Antibacterial Properties for Textile Coating
Published in ACS applied nano materials (22-10-2021)“…Textiles that protect against bacterial nosocomial infections are vital owing to the associated high morbidity, mortality, and a series of challenges that…”
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19
NRF1‐mediated mitochondrial biogenesis antagonizes innate antiviral immunity
Published in The EMBO journal (15-08-2023)“…Mitochondrial biogenesis is the process of generating new mitochondria to maintain cellular homeostasis. Here, we report that viruses exploit mitochondrial…”
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Nondegradable ubiquitinated ATG9A organizes Golgi integrity and dynamics upon stresses
Published in Cell reports (Cambridge) (16-08-2022)“…ATG9A is a highly conserved membrane protein required for autophagy initiation. It is trafficked from the trans-Golgi network (TGN) to the phagophore to act as…”
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