Search Results - "Mrowka, Piotr"
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Raman Spectroscopy as a Research and Diagnostic Tool in Clinical Hematology and Hematooncology
Published in International journal of molecular sciences (16-03-2024)“…Raman spectroscopy is a molecular spectroscopic technique able to provide detailed information about the chemical structure, phase, crystallinity, and…”
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Effect of substrate stiffness on the osteogenic differentiation of bone marrow stem cells and bone-derived cells
Published in Cell biology international (01-06-2013)“…There is a profound dependence of cell behaviour on the stiffness of its microenvironment. To gain a better understanding of the regulation of cellular…”
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P656: NOVEL THIAZOLIDINEDIONE WITH HDAC INHIBITING PROPERTIES OPTIMIZED FOR CHRONIC MYELOID LEUKEMIA TREATMENT
Published in HemaSphere (08-08-2023)Get full text
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P393: GENETIC CHARACTERISTICS OF PEDIATRIC B‐OTHER ACUTE LYMPHOBLASTIC LEUKEMIA COHORT USING TARGETED RNA SEQUENCING
Published in HemaSphere (08-08-2023)Get full text
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PB1710: AN EXTENDED FLOW CYTOMETRY PANEL AS A SCREENING TOOL FOR PH‐LIKE ALL
Published in HemaSphere (08-08-2023)Get full text
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Statins inhibit ABCB1 and ABCG2 drug transporter activity in chronic myeloid leukemia cells and potentiate antileukemic effects of imatinib
Published in Experimental hematology (01-06-2014)“…Despite undisputed success of tyrosine kinase inhibitors in the therapy of chronic myeloid leukemia (CML), development of drug resistance and inability to cure…”
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Statins impair antitumor effects of rituximab by inducing conformational changes of CD20
Published in PLoS medicine (01-03-2008)“…Rituximab is used in the treatment of CD20+ B cell lymphomas and other B cell lymphoproliferative disorders. Its clinical efficacy might be further improved by…”
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Multifunctional composite combining chitosan microspheres for drug delivery embedded in shape memory polyester-urethane matrix
Published in Composites science and technology (05-01-2021)“…Multifunctional composite biomaterials (3b-PU/CH_M) consisting of chitosan microspheres (CH-M) that provide drug release functionality and crosslinked…”
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Studies on enzymatic degradation of multifunctional composite consisting of chitosan microspheres and shape memory polyurethane matrix
Published in Polymer degradation and stability (01-12-2020)“…•In vitro degradation studies of 3b-PU/CH-M composite consisting of chitosan microspheres (CH-M) embedded in polyester-urethane matrix were performed in…”
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Cytotoxic Potential of Bioactive Compounds from Aspergillus flavus , an Endophytic Fungus Isolated from Cynodon dactylon, against Breast Cancer: Experimental and Computational Approach
Published in Molecules (Basel, Switzerland) (12-12-2022)“…Endophytic fungi are a diverse group of microorganisms that colonize the inter- or intracellular spaces of plants and exhibit mutual benefits. Their…”
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Dynamic Changes in the Ability to Release Neutrophil ExtraCellular Traps in the Course of Childhood Acute Leukemias
Published in International journal of molecular sciences (15-01-2021)“…Acute leukemias, the most common cancers in children, are characterized by excessive proliferation of malignant progenitor cells. As a consequence of impaired…”
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l-Ornithine-N5-monooxygenase (PvdA) Substrate Analogue Inhibitors for Pseudomonas aeruginosa Infections Treatment: Drug Repurposing Computational Studies
Published in Biomolecules (Basel, Switzerland) (25-06-2022)“…is an opportunistic pathogen that can cause acute and severe infections. Increasing resistance to antibiotics has given rise to the urgent need for an…”
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Proteasome Inhibition Potentiates Antitumor Effects of Photodynamic Therapy in Mice through Induction of Endoplasmic Reticulum Stress and Unfolded Protein Response
Published in Cancer research (Chicago, Ill.) (15-05-2009)“…Photodynamic therapy (PDT) is an approved therapeutic procedure that exerts cytotoxic activity toward tumor cells by inducing production of reactive oxygen…”
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Design and in vitro evaluation of electrospun shape memory polyurethanes for self-fitting tissue engineering grafts and drug delivery systems
Published in Materials Science & Engineering C (01-05-2020)“…Integration of multiple features including shape memory, biodegradation, and sustained drug delivery in a single material offers the opportunity to…”
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Alterations in lipid metabolism accompanied by changes in protein and carotenoid content as spectroscopic markers of human T cell activation
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-06-2024)“…This work aims to understand better the mechanism of cellular processes accompanying the activation of human T cells and to develop a novel, fast, label-free…”
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P1374: RAMAN SPECTROSCOPY STUDIES OF IMMUNE RESPONSE ELEMENTS
Published in HemaSphere (08-08-2023)Get full text
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Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells
Published in European journal of pharmaceutical sciences (01-11-2020)“…•A series of novel permuted thiazolidinedione derivatives were designed and synthesized as GLUT1 inhibitors.•The representative Compound G5 demonstrated GLUT1,…”
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Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential
Published in European journal of medicinal chemistry (15-09-2020)“…Cancer cells increase their glucose uptake and glycolytic activity to meet the high energy requirements of proliferation. Glucose transporters (GLUTs), which…”
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Discovery of 5-naphthylidene-2,4-thiazolidinedione derivatives as selective HDAC8 inhibitors and evaluation of their cytotoxic effects in leukemic cell lines
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] •Selective and Non-hydroxamate HDAC8 inhibitors instead pan inhibitors.•5-Naphthylidene-2,4-thiazolidinedione derivatives were designed and…”
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