Search Results - "Mrestani, Achmed"
-
1
Enhanced Performance of the Optimized Dye CF583R in Direct Stochastic Optical Reconstruction Microscopy of Active Zones in Drosophila Melanogaster
Published in Cells (Basel, Switzerland) (28-08-2024)“…Super-resolution single-molecule localization microscopy (SMLM) of presynaptic active zones (AZs) and postsynaptic densities contributed to the observation of…”
Get full text
Journal Article -
2
Active zone compaction correlates with presynaptic homeostatic potentiation
Published in Cell reports (Cambridge) (05-10-2021)“…Neurotransmitter release is stabilized by homeostatic plasticity. Presynaptic homeostatic potentiation (PHP) operates on timescales ranging from minute- to…”
Get full text
Journal Article -
3
Single-Molecule Localization Microscopy of Presynaptic Active Zones in Drosophila melanogaster after Rapid Cryofixation
Published in International journal of molecular sciences (21-01-2023)“…Single-molecule localization microscopy (SMLM) greatly advances structural studies of diverse biological tissues. For example, presynaptic active zone (AZ)…”
Get full text
Journal Article -
4
Versatile Endogenous Editing of GluRIIA in Drosophila melanogaster
Published in Cells (Basel, Switzerland) (10-02-2024)“…Glutamate receptors at the postsynaptic side translate neurotransmitter release from presynapses into postsynaptic excitation. They play a role in many forms…”
Get full text
Journal Article -
5
Endogenous tagging of Unc-13 reveals nanoscale reorganization at active zones during presynaptic homeostatic potentiation
Published in Frontiers in cellular neuroscience (14-12-2022)“…Neurotransmitter release at presynaptic active zones (AZs) requires concerted protein interactions within a dense 3D nano-hemisphere. Among the complex protein…”
Get full text
Journal Article -
6
Altered gene expression profiles impair the nervous system development in individuals with 15q13.3 microdeletion
Published in Scientific reports (05-08-2022)“…The 15q13.3 microdeletion has pleiotropic effects ranging from apparently healthy to severely affected individuals. The underlying basis of the variable…”
Get full text
Journal Article -
7
Targeted volumetric single-molecule localization microscopy of defined presynaptic structures in brain sections
Published in Communications biology (25-03-2021)“…Revealing the molecular organization of anatomically precisely defined brain regions is necessary for refined understanding of synaptic plasticity. Although…”
Get full text
Journal Article -
8
Does diabetes mellitus affect the safety profile of valproic acid for the treatment of status epilepticus? A retrospective cohort study
Published in Neurological research and practice (24-10-2022)“…Abstract Background In the treatment of status epilepticus less is known about the influence of comorbidities on the safety profile of anticonvulsive drugs…”
Get full text
Journal Article -
9
Versatile Endogenous Editing of GluRIIA in IDrosophila melanogaster/I
Published in Cells (Basel, Switzerland) (01-02-2024)“…Glutamate receptors at the postsynaptic side translate neurotransmitter release from presynapses into postsynaptic excitation. They play a role in many forms…”
Get full text
Journal Article -
10
The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release
Published in Brain (London, England : 1878) (21-11-2022)“…Humans carrying the CORD7 (cone-rod dystrophy 7) mutation possess increased verbal IQ and working memory. This autosomal dominant syndrome is caused by the…”
Get full text
Journal Article -
11
Nanoscaled RIM clustering at presynaptic active zones revealed by endogenous tagging
Published in Life science alliance (01-12-2023)“…Chemical synaptic transmission involves neurotransmitter release from presynaptic active zones (AZs). The AZ protein Rab-3-interacting molecule (RIM) is…”
Get full text
Journal Article -
12
Improving one-step scarless genome editing in Drosophila melanogaster by combining ovo D co-CRISPR selection with sgRNA target site masking
Published in Biology methods and protocols (2022)“…The precise and rapid construction of alleles through CRISPR/Cas9-mediated genome engineering renders a powerful animal system for molecular structure-function…”
Get full text
Journal Article -
13
Improving one-step scarless genome editing in Drosophila melanogaster by combining ovoD co-CRISPR selection with sgRNA target site masking
Published in Biology methods and protocols (10-01-2022)“…Abstract The precise and rapid construction of alleles through CRISPR/Cas9-mediated genome engineering renders Drosophila melanogaster a powerful animal system…”
Get full text
Journal Article