Search Results - "Mpabalwani, Evans"
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Burden and Epidemiology of Rotavirus Diarrhea in Selected African Countries: Preliminary Results from the African Rotavirus Surveillance Network
Published in The Journal of infectious diseases (01-09-2010)“…Severe rotavirus diarrhea in children <5 years of age is a major public health problem; however, limited regional and country specific data on rotavirus…”
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Malaria is the leading cause of acute kidney injury among a Zambian paediatric renal service cohort retrospectively evaluated for aetiologies, predictors of the need for dialysis, and outcomes
Published in PloS one (25-10-2023)“…Background Whilst malaria is a prominent aetiology associated with acute kidney injury (AKI) in many parts of Africa, a shift in the traditional AKI…”
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Impact of Rotavirus Vaccination on Diarrheal Hospitalizations in Children Aged <5 Years in Lusaka, Zambia
Published in Clinical infectious diseases (01-05-2016)“…Background. Monovalent rotavirus vaccine was introduced in the routine public health immunization program in Lusaka, Zambia, in January 2012 and was rolled out…”
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Rotavirus breakthrough infections responsible for gastroenteritis in vaccinated infants who presented with acute diarrhoea at University Teaching Hospitals, Children's Hospital in 2016, in Lusaka Zambia
Published in PloS one (04-02-2021)“…In Zambia, before rotavirus vaccine introduction, the virus accounted for about 10 million episodes of diarrhoea, 63 000 hospitalisations and 15 000 deaths in…”
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Whole Genome Analysis of Human Rotaviruses Reveals Single Gene Reassortant Rotavirus Strains in Zambia
Published in Viruses (18-09-2021)“…Rotarix vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole…”
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Risk Factors Associated With Increased Mortality From Intussusception in African Infants
Published in Journal of pediatric gastroenterology and nutrition (01-01-2020)“…ABSTRACT Objectives: Morbidity and mortality from intussusception, the leading cause of bowel obstruction in infants, is higher in Africa than in other regions…”
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Zinc absorption from biofortified maize meets the requirements of young rural Zambian children
Published in The Journal of nutrition (01-03-2015)“…The zinc content of maize, a major global food staple, is generally insufficient alone to meet the requirements of young children. The primary objective of…”
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The Burden of Invasive Bacterial Disease and the Impact of 10-Valent Pneumococcal Conjugate Vaccine in Children <5 years hospitalized for Meningitis in Lusaka, Zambia, 2010-2019
Published in The Journal of infectious diseases (01-09-2021)“…Despite the availability of vaccines, invasive bacterial diseases remain a public health concern and cause childhood morbidity and mortality. We investigated…”
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Children infected by human herpesvirus 6B with febrile seizures are more likely to develop febrile status epilepticus: A case‐control study in a referral hospital in Zambia
Published in Journal of medical virology (01-11-2018)“…Background Human herpesvirus 6B (HHV‐6B) is the causative agent of Roseola infantum, and has also been suggested to play a role in the pathogenesis of febrile…”
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Perspectives on development and advancement of new tuberculosis vaccines
Published in International journal of infectious diseases (01-04-2024)“…•Development of novel vaccines has been slow, and tuberculosis (TB) remains a neglected disease.•Drug-resistant TB is rising in incidence because of the recent…”
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Genomic Analysis of G2P[4] Group A Rotaviruses in Zambia Reveals Positive Selection in Amino Acid Site 7 of Viral Protein 3
Published in Viruses (01-02-2023)“…The G2P[4] genotype is among the rotavirus strains that circulate commonly in humans. Several countries have reported its immediate upsurge after the…”
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Declines in Pneumonia and Meningitis Hospitalizations in Children Under 5 Years of Age After Introduction of 10-Valent Pneumococcal Conjugate Vaccine in Zambia, 2010–2016
Published in Clinical infectious diseases (05-09-2019)“…Abstract Background Pneumococcus is a leading cause of pneumonia and meningitis. Zambia introduced a 10-valent pneumococcal conjugate vaccine (PCV10) in July…”
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Diversity of rotavirus strains circulating in children under five years of age who presented with acute gastroenteritis before and after rotavirus vaccine introduction, University Teaching Hospital, Lusaka, Zambia, 2008–2015
Published in Vaccine (12-11-2018)“…Following the introduction of rotavirus vaccine into the routine immunization schedule, the burden of rotavirus disease has significantly reduced in Zambia…”
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Safety and immunogenicity of a live attenuated pentavalent rotavirus vaccine in HIV-exposed infants with or without HIV infection in Africa
Published in AIDS (London) (02-01-2017)“…OBJECTIVE:Although many HIV-infected (HIV+) and HIV-exposed but uninfected (HEU) infants have received live rotavirus vaccines since the WHO recommended…”
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An Unusual Cause of Lymphadenopathy: Rosai Dorfman Disease in a 7-Year-Old Female Zambian Child: Case Report and Literature Review
Published in Clinical medicine insights. Case reports (01-01-2024)“…Rosai Dorfman disease (RDD) is a rare non-Langerhans histiocytic disorder, which belongs to the R group of the 2016 revised histiocytic classification. It's…”
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Review of Naturally Occurring Intussusception in Young Children in the WHO African Region prior to the Era of Rotavirus Vaccine Utilization in the Expanded Programme of Immunization
Published in Journal of tropical pediatrics (1980) (01-06-2017)“…Rotavirus vaccines, Rotarix and RotaTeq, are increasingly being introduced in national immunization programmes in Africa to prevent severe dehydrating acute…”
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Safety of artemether-lumefantrine in pregnant women with malaria: results of a prospective cohort study in Zambia
Published in Malaria journal (01-09-2010)“…Safety data regarding exposure to artemisinin-based combination therapy in pregnancy are limited. This prospective cohort study conducted in Zambia evaluated…”
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Molecular Characterisation of a Rare Reassortant Porcine-Like G5P[6] Rotavirus Strain Detected in an Unvaccinated Child in Kasama, Zambia
Published in Pathogens (Basel) (17-08-2020)“…A human-porcine reassortant strain, RVA/Human-wt/ZMB/UFS-NGS-MRC-DPRU4723/2014/G5P[6], was identified in a sample collected in 2014 from an unvaccinated 12…”
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Multicountry Analysis of Spectrum of Clinical Manifestations of Children <5 Years of Age Hospitalized with Diarrhea
Published in Emerging infectious diseases (01-12-2019)“…After introduction of rotavirus vaccine, other pathogens might become leading causes of hospitalizations for severe diarrhea among children <5 years of age…”
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Intussusception Incidence Rates in 9 Zambian Hospitals, 2007–2011: Prerotavirus Vaccine Introduction
Published in The Pediatric infectious disease journal (01-01-2014)“…BACKGROUND:Intussusception, a rare adverse event associated with rotavirus vaccines in some settings, is a common cause of intestinal obstruction in infants…”
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