Synthesis of β-triazolyl sulfones via the reaction of vinyl sulfones with 1,2,4-triazoles under basic conditions

A method was developed for the synthesis of β-triazolyl sulfones from vinylsulfones and 1,2,4-triazoles in the presence of sodium triazolide taken as the base. The reaction was carried out in DMSO at room temperature for 120 h. The target compounds were obtained in 25–89% yields.

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Bibliographic Details
Published in:Russian chemical bulletin Vol. 71; no. 7; pp. 1544 - 1548
Main Authors: Radulov, P. S., Mozzhegorov, A. V., Mulina, O. M., Yaremenko, I. A., Ilovaisky, A. I., Terent’ev, A. O.
Format: Journal Article
Language:English
Published: New York Springer US 01-07-2022
Springer Nature B.V
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Summary:A method was developed for the synthesis of β-triazolyl sulfones from vinylsulfones and 1,2,4-triazoles in the presence of sodium triazolide taken as the base. The reaction was carried out in DMSO at room temperature for 120 h. The target compounds were obtained in 25–89% yields.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-022-3562-7