Search Results - "Mozzer, Ann"

Machine learning-driven multifunctional peptide engineering for sustained ocular drug delivery by Hsueh, Henry T., Chou, Renee Ti, Rai, Usha, Liyanage, Wathsala, Kim, Yoo Chun, Appell, Matthew B., Pejavar, Jahnavi, Leo, Kirby T., Davison, Charlotte, Kolodziejski, Patricia, Mozzer, Ann, Kwon, HyeYoung, Sista, Maanasa, Anders, Nicole M., Hemingway, Avelina, Rompicharla, Sri Vishnu Kiran, Edwards, Malia, Pitha, Ian, Hanes, Justin, Cummings, Michael P., Ensign, Laura M.

“…Sustained drug delivery strategies have many potential benefits for treating a range of diseases, particularly chronic diseases that require treatment for…”
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Antagonism of Quorum Sensing Phenotypes by Analogs of the Marine Bacterial Secondary Metabolite 3-Methyl- N -(2'-Phenylethyl)-Butyramide by Meschwitz, Susan M, Teasdale, Margaret E, Mozzer, Ann, Martin, Nicole, Liu, Jiayuan, Forschner-Dancause, Stephanie, Rowley, David C

“…Quorum sensing (QS) antagonists have been proposed as novel therapeutic agents to combat bacterial infections. We previously reported that the secondary…”
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Nanofiber‐based glaucoma drainage implant improves surgical outcomes by modulating fibroblast behavior by Josyula, Aditya, Mozzer, Ann, Szeto, Julia, Ha, Youlim, Richmond, Nicole, Chung, Seung Woo, Rompicharla, Sri Vishnu Kiran, Narayan, Janani, Ramesh, Samiksha, Hanes, Justin, Ensign, Laura, Parikh, Kunal, Pitha, Ian

“…Biomaterials are implanted in millions of individuals worldwide each year. Both naturally derived and synthetic biomaterials induce a foreign body reaction…”
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Cyclic strain alters the transcriptional and migratory response of scleral fibroblasts to TGFβ by Mozzer, Ann, Pitha, Ian

“…In glaucoma, scleral fibroblasts are exposed to IOP-associated mechanical strain and elevated TGFβ levels. These stimuli, in turn, lead to scleral remodeling…”
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Targeted Microglial Attenuation through Dendrimer–Drug Conjugates Improves Glaucoma Neuroprotection by Pitha, Ian, Kambhampati, Siva, Sharma, Anjali, Sharma, Rishi, McCrea, Liam, Mozzer, Ann, Kannan, Rangaramanujam M.

“…Retinal microglial/macrophage activation and optic nerve (ON) microglial/macrophage activation are glaucoma biomarkers and potential therapeutic targets for…”
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Regional Differences and Physiologic Behaviors in Peripapillary Scleral Fibroblasts by Szeto, Julia, Chow, Amanda, McCrea, Liam, Mozzer, Ann, Nguyen, Thao D, Quigley, Harry A, Pitha, Ian

“…The purpose of this study was to describe the cellular architecture of normal human peripapillary sclera (PPS) and evaluate surface topography's role in…”
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Engineered peptide-drug conjugate provides sustained protection of retinal ganglion cells with topical administration in rats by Hsueh, Henry T., Chou, Renee Ti, Rai, Usha, Kolodziejski, Patricia, Liyanage, Wathsala, Pejavar, Jahnavi, Mozzer, Ann, Davison, Charlotte, Appell, Matthew B., Kim, Yoo Chun, Leo, Kirby T., Kwon, HyeYoung, Sista, Maanasa, Anders, Nicole M., Hemingway, Avelina, Rompicharla, Sri Vishnu Kiran, Pitha, Ian, Zack, Donald J., Hanes, Justin, Cummings, Michael P., Ensign, Laura M.

“…Effective eye drop delivery systems for treating diseases of the posterior segment have yet to be clinically validated. Further, adherence to eye drop regimens…”
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