Search Results - "Mozsary, Christopher"
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Multi-omic, Single-Cell, and Biochemical Profiles of Astronauts Guide Pharmacological Strategies for Returning to Gravity
Published in Cell reports (Cambridge) (08-12-2020)“…The National Aeronautics and Space Administration (NASA) Twins Study created an integrative molecular profile of an astronaut during NASA’s first 1-year…”
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Borg extrachromosomal elements of methane-oxidizing archaea have conserved and expressed genetic repertoires
Published in Nature communications (26-06-2024)“…Borgs are huge extrachromosomal elements (ECE) of anaerobic methane-consuming “ Candidatus Methanoperedens” archaea. Here, we used nanopore sequencing to…”
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Clonal hematopoiesis before, during, and after human spaceflight
Published in Cell reports (Cambridge) (09-02-2021)Get full text
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Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions
Published in Nature communications (12-03-2021)“…In less than nine months, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) killed over a million people, including >25,000 in New York City…”
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Telomere Length Dynamics and DNA Damage Responses Associated with Long-Duration Spaceflight
Published in Cell reports (Cambridge) (08-12-2020)“…Telomere length dynamics and DNA damage responses were assessed before, during, and after one-year or shorter duration missions aboard the International Space…”
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Betacoronavirus-specific alternate splicing
Published in Genomics (San Diego, Calif.) (01-03-2022)“…Viruses can subvert a number of cellular processes including splicing in order to block innate antiviral responses, and many viruses interact with cellular…”
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Clonal Hematopoiesis Before, During, and After Human Spaceflight
Published in Cell reports (Cambridge) (08-12-2020)“…Clonal hematopoiesis (CH) occurs when blood cells harboring an advantageous mutation propagate faster than others. These mutations confer a risk for…”
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Towards geospatially-resolved public-health surveillance via wastewater sequencing
Published in Nature communications (27-09-2024)“…Wastewater is a geospatially- and temporally-linked microbial fingerprint of a given population, making it a potentially valuable tool for tracking public…”
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A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
Published in Journal of biomolecular techniques (01-09-2021)“…The COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates…”
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System-wide transcriptome damage and tissue identity loss in COVID-19 patients
Published in Cell reports. Medicine (15-02-2022)“…The molecular mechanisms underlying the clinical manifestations of coronavirus disease 2019 (COVID-19), and what distinguishes them from common seasonal…”
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