Search Results - "Mozolewski, Paweł"
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Oxidative Stress as an Important Contributor to the Pathogenesis of Psoriasis
Published in International journal of molecular sciences (27-08-2020)“…This review discusses how oxidative stress (OS), an imbalance between oxidants and antioxidants in favor of the oxidants, increased production of reactive…”
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The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
Published in The Journal of biological chemistry (13-06-2014)“…Genistein (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) has been previously proposed as a potential drug for use in substrate reduction therapy for…”
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Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington’s disease patients
Published in Metabolic brain disease (01-12-2018)“…Huntington disease (HD) is an autosomal dominant neurodegenerative disorder manifesting as progressive impairment of motor function and different…”
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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Published in Scientific reports (23-03-2015)“…Flavonoids were found previously to modulate efficiency of synthesis of glycosaminoglycans (GAGs), compounds which are accumulated in cells of patients…”
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Differential RNA editing landscapes in host cell versus the SARS-CoV-2 genome
Published in iScience (17-11-2023)“…The SARS-CoV-2 pandemic was defined by the emergence of new variants formed through virus mutation originating from random errors not corrected by viral…”
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Non-steroidal anti-inflammatory drugs are safe with respect to the transcriptome of human dermal fibroblasts
Published in European journal of pharmacology (05-01-2018)“…Non-steroidal anti-inflammatory drugs (NSAIDs) provide important benefits to millions of patients, but are associated with a number of serious adverse events…”
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Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways
Published in Scientific reports (27-02-2017)“…In this report, selected non-steroidal anti-inflammatory drugs (NSAIDs), indomethacin and nimesulide, and analgesics acetaminophen, alone, as well as in…”
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Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Published in Scientific reports (09-12-2016)Get full text
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Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Published in Scientific reports (31-03-2016)Get full text
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Published in Scientific reports (09-12-2016)“…Scientific Reports 5: Article number: 9378; published online: 23 March 2015; updated: 09 December 2016…”
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Correction: Corrigendum: Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
Published in Scientific reports (31-03-2016)“…Scientific Reports 5: Article number: 9378; published online: 23 March 2015; updated: 31 March 2016 This Article contains an error in Figure 3, where the…”
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Familial Alzheimer’s disease-associated PSEN1 mutations affect neurodevelopment through increased Notch signaling
Published in Stem cell reports (11-07-2023)“…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, but its root cause may lie in neurodevelopment. PSEN1 mutations cause the majority of…”
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The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health
Published in Journal of cell science (15-04-2021)“…Nuclear Ca2+ has emerged as one of the most potent mediators of the dialogue between neuronal synapses and the nucleus that regulates heterochromatin states,…”
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The molecular mechanism of genistein action in lysosomal storage diseases: A transcriptomic approach
Published in Molecular genetics and metabolism (01-02-2013)Get full text
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