Search Results - "Mozolewski, Paweł"

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  1. 1

    Oxidative Stress as an Important Contributor to the Pathogenesis of Psoriasis by Pleńkowska, Joanna, Gabig-Cimińska, Magdalena, Mozolewski, Paweł

    “…This review discusses how oxidative stress (OS), an imbalance between oxidants and antioxidants in favor of the oxidants, increased production of reactive…”
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    Journal Article
  2. 2

    The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation by Moskot, Marta, Montefusco, Sandro, Jakóbkiewicz-Banecka, Joanna, Mozolewski, Paweł, Węgrzyn, Alicja, Di Bernardo, Diego, Węgrzyn, Grzegorz, Medina, Diego L., Ballabio, Andrea, Gabig-Cimińska, Magdalena

    Published in The Journal of biological chemistry (13-06-2014)
    “…Genistein (5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one) has been previously proposed as a potential drug for use in substrate reduction therapy for…”
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    Journal Article
  3. 3

    Mitochondrial alterations accompanied by oxidative stress conditions in skin fibroblasts of Huntington’s disease patients by Jędrak, Paulina, Mozolewski, Paweł, Węgrzyn, Grzegorz, Więckowski, Mariusz R.

    Published in Metabolic brain disease (01-12-2018)
    “…Huntington disease (HD) is an autosomal dominant neurodegenerative disorder manifesting as progressive impairment of motor function and different…”
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    Journal Article
  4. 4

    Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids by Moskot, Marta, Jakóbkiewicz-Banecka, Joanna, Kloska, Anna, Smolińska, Elwira, Mozolewski, Paweł, Malinowska, Marcelina, Rychłowski, Michał, Banecki, Bogdan, Węgrzyn, Grzegorz, Gabig-Cimińska, Magdalena

    Published in Scientific reports (23-03-2015)
    “…Flavonoids were found previously to modulate efficiency of synthesis of glycosaminoglycans (GAGs), compounds which are accumulated in cells of patients…”
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    Journal Article
  5. 5

    Differential RNA editing landscapes in host cell versus the SARS-CoV-2 genome by Kurkowiak, Małgorzata, Fletcher, Sarah, Daniels, Alison, Mozolewski, Paweł, Silvestris, Domenico Alessandro, Król, Ewelina, Marek-Trzonkowska, Natalia, Hupp, Ted, Tait-Burkard, Christine

    Published in iScience (17-11-2023)
    “…The SARS-CoV-2 pandemic was defined by the emergence of new variants formed through virus mutation originating from random errors not corrected by viral…”
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    Journal Article
  6. 6

    Non-steroidal anti-inflammatory drugs are safe with respect to the transcriptome of human dermal fibroblasts by Mozolewski, Paweł, Jakóbkiewicz-Banecka, Joanna, Węgrzyn, Grzegorz, Banecki, Bogdan, Gabig-Cimińska, Magdalena

    Published in European journal of pharmacology (05-01-2018)
    “…Non-steroidal anti-inflammatory drugs (NSAIDs) provide important benefits to millions of patients, but are associated with a number of serious adverse events…”
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  7. 7

    Nonsteroidal anti-inflammatory drugs modulate cellular glycosaminoglycan synthesis by affecting EGFR and PI3K signaling pathways by Mozolewski, Paweł, Moskot, Marta, Jakóbkiewicz-Banecka, Joanna, Węgrzyn, Grzegorz, Bocheńska, Katarzyna, Banecki, Bogdan, Gabig-Cimińska, Magdalena

    Published in Scientific reports (27-02-2017)
    “…In this report, selected non-steroidal anti-inflammatory drugs (NSAIDs), indomethacin and nimesulide, and analgesics acetaminophen, alone, as well as in…”
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    Journal Article
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    Familial Alzheimer’s disease-associated PSEN1 mutations affect neurodevelopment through increased Notch signaling by Hurley, Erin M., Mozolewski, Pawel, Dobrowolski, Radek, Hsieh, Jenny

    Published in Stem cell reports (11-07-2023)
    “…Alzheimer’s disease (AD) is the most common neurodegenerative disorder, but its root cause may lie in neurodevelopment. PSEN1 mutations cause the majority of…”
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    Journal Article
  13. 13

    The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health by Mozolewski, Pawel, Jeziorek, Maciej, Schuster, Christoph M, Bading, Hilmar, Frost, Bess, Dobrowolski, Radek

    Published in Journal of cell science (15-04-2021)
    “…Nuclear Ca2+ has emerged as one of the most potent mediators of the dialogue between neuronal synapses and the nucleus that regulates heterochromatin states,…”
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