Search Results - "Moya, Eva"
-
1
Activity of BET-proteolysis targeting chimeric (PROTAC) compounds in triple negative breast cancer
Published in Journal of experimental & clinical cancer research (30-08-2019)“…Triple negative breast cancer (TNBC) is an incurable disease where novel therapeutic strategies are needed. Proteolysis targeting chimeric (PROTAC) are novel…”
Get full text
Journal Article -
2
Synthetic Lethality Interaction Between Aurora Kinases and CHEK1 Inhibitors in Ovarian Cancer
Published in Molecular cancer therapeutics (01-11-2017)“…Ovarian cancer is characterized by frequent mutations at TP53. These tumors also harbor germline mutations at homologous recombination repair genes, so they…”
Get full text
Journal Article -
3
Transcriptomic immunologic signature associated with favorable clinical outcome in basal-like breast tumors
Published in PloS one (04-05-2017)“…Most patients with early stage triple negative breast cancer (TNBC) receive adjuvant chemotherapy. Activation of the immune system is associated with tumor…”
Get full text
Journal Article -
4
Photovoice: Integrating Course-Based Research in Undergraduate and Graduate Social Work Education
Published in The British journal of social work (01-03-2021)“…Abstract Research skills are vital to students’ professional careers and must be cultivated in the social work curriculum. While students and faculty may…”
Get full text
Journal Article -
5
Human Papillomavirus Vaccine Acceptance (HPV-VA) and Vaccine Uptake (HPV-VU): assessing the impact of theory, culture, and trusted sources of information in a Hispanic community
Published in BMC public health (14-09-2023)“…Abstract Background Human papillomavirus (HPV) is the most common sexually transmitted infection and is associated with many types of cancers that…”
Get full text
Journal Article -
6
Isolation and Characterization of Nitrate-Reducing Bacteria as Potential Probiotics for Oral and Systemic Health
Published in Frontiers in microbiology (15-09-2020)“…Recent evidence indicates that the reduction of salivary nitrate by oral bacteria can contribute to prevent oral diseases, as well as increase systemic nitric…”
Get full text
Journal Article -
7
Pharmacological screening and transcriptomic functional analyses identify a synergistic interaction between dasatinib and olaparib in triple‐negative breast cancer
Published in Journal of cellular and molecular medicine (01-03-2020)“…Identification of druggable vulnerabilities is a main objective in triple‐negative breast cancer (TNBC), where no curative therapies exist. Gene set enrichment…”
Get full text
Journal Article -
8
Genetic mutational status of genes regulating epigenetics: Role of the histone methyltransferase KMT2D in triple negative breast tumors
Published in PloS one (16-04-2019)“…Epigenetic regulating proteins like histone methyltransferases produce variations in several functions, some of them associated with the generation of…”
Get full text
Journal Article -
9
Functional transcriptomic annotation and protein–protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer
Published in Breast cancer research and treatment (01-04-2018)“…Purpose Although obesity is a risk factor for breast cancer, little effort has been made in the identification of druggable molecular alterations in…”
Get full text
Journal Article -
10
Effect of Executive Functioning, Decision-Making and Self-Reported Impulsivity on the Treatment Outcome of Pathologic Gambling
Published in Journal of psychiatry & neuroscience (01-05-2011)“…Background Impairments in self-regulatory behaviour reflect a deficit in executive functioning and decision-making, as well as higher levels of self-reported…”
Get full text
Journal Article -
11
Roman and medieval crops in the Iberian Peninsula: A first overview of seeds and fruits from archaeological sites
Published in Quaternary international (02-01-2019)“…This paper presents an overview of the current state of research on Roman, Late Antique and medieval agriculture in the Iberian Peninsula through the study of…”
Get full text
Journal Article -
12
Integration of Social, Cultural, and Biomedical Strategies into an Existing Couple-Based Behavioral HIV/STI Prevention Intervention: Voices of Latino Male Couples
Published in PloS one (30-03-2016)“…Successful HIV prevention and treatment requires evidence-based approaches that combine biomedical strategies with behavioral interventions that are socially…”
Get full text
Journal Article -
13
Antitumoral Activity of a CDK9 PROTAC Compound in HER2-Positive Breast Cancer
Published in International journal of molecular sciences (13-05-2022)“…Cyclin-dependent kinases (CDKs) are a broad family of proteins involved in the cell cycle and transcriptional regulation. In this article, we explore the…”
Get full text
Journal Article -
14
Infant-gut associated Bifidobacterium dentium strains utilize the galactose moiety and release lacto-N-triose from the human milk oligosaccharides lacto-N-tetraose and lacto-N-neotetraose
Published in Scientific reports (02-12-2021)“…Much evidence suggests a role for human milk oligosaccharides (HMOs) in establishing the infant microbiota in the large intestine, but the response of…”
Get full text
Journal Article -
15
Hispanic Survivors and Caregivers of Human Papillomavirus–Associated Cancers: Lived Experiences in a U.S.–Mexico Border Community
Published in Health education & behavior (01-10-2023)“…Although human papillomavirus (HPV)-associated cancers are preventable and treatable at early stages, health disparities in HPV-associated cancer outcomes…”
Get full text
Journal Article -
16
Expression of MHC class I, HLA-A and HLA-B identifies immune-activated breast tumors with favorable outcome
Published in Oncoimmunology (03-10-2019)“…Antigen recognition by MHC class I molecules is a key step for the initiation of the immune response. We hypothesized that expression of these molecules could…”
Get full text
Journal Article -
17
Evaluation of transcriptionally regulated genes identifies NCOR1 in hormone receptor negative breast tumors and lung adenocarcinomas as a potential tumor suppressor gene
Published in PloS one (28-11-2018)“…Regulation of transcription is a key process in cellular homeostasis. It depends on regulators that either repress or stimulate the transcription of genes,…”
Get full text
Journal Article -
18
MZ1 co-operates with trastuzumab in HER2 positive breast cancer
Published in Journal of experimental & clinical cancer research (19-03-2021)“…Although the anti-HER2 antibody trastuzumab augments patient survival in HER2+ breast cancer, a relevant number of patients progress to this treatment. In this…”
Get full text
Journal Article -
19
Intensification of corn fiber saccharification using a tailor made enzymatic cocktail
Published in Enzyme and microbial technology (01-01-2024)“…The transition from an economic model based on resource extraction to a more sustainable and circular economy requires the development of innovative methods to…”
Get full text
Journal Article -
20
Differential Proteomic Analysis of Human Glioblastoma and Neural Stem Cells Reveals HDGF as a Novel Angiogenic Secreted Factor
Published in Stem cells (Dayton, Ohio) (01-05-2012)“…Presence in glioblastomas of cancer cells with normal neural stem cell (NSC) properties, tumor initiating capacity, and resistance to current therapies…”
Get full text
Journal Article