Search Results - "Moxham, Cary P."
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Site-specific Conjugation on Serine → Cysteine Variant Monoclonal Antibodies
Published in The Journal of biological chemistry (29-09-2000)“…We have engineered a cysteine residue at position 442 (EU/OU numbering) in the third constant domain (CH3) of the heavy chain of several IgGs with different…”
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Toward Antibody-directed Enzyme Prodrug Therapy with the T268G Mutant of Human Carboxypeptidase A1 and Novel in VivoStable Prodrugs of Methotrexate
Published in The Journal of biological chemistry (20-06-1997)“…Antibody-directed enzyme prodrug therapy (ADEPT) has the potential of greatly enhancing antitumor selectivity of cancer therapy by synthesizing…”
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3
Fat cell .beta.1-adrenergic receptor: structural evidence for existence of disulfide bridges essential for ligand binding
Published in Biochemistry (Easton) (01-10-1985)Get full text
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Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate
Published in The Journal of biological chemistry (20-06-1997)“…Antibody-directed enzyme prodrug therapy (ADEPT) has the potential of greatly enhancing antitumor selectivity of cancer therapy by synthesizing…”
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5
Insulin/IGF-I receptor hybrids: a mechanism for increasing receptor diversity
Published in Journal of cellular biochemistry (01-02-1992)“…Insulin and IGF-I receptors are homologous disulfide linked alpha 2 beta 2 tetramers. These tetramers are formed biosynthetically when proreceptors containing…”
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6
Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor
Published in Endocrinology (Philadelphia) (01-03-1992)“…Stimulation by insulin-like growth factor-I (IGF-I) of LISN C4 cells, a mouse fibroblast cell line that overexpresses human IGF-I receptors, led to an increase…”
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7
Expression and Characterization of Human Pancreatic Preprocarboxypeptidase A1 and Preprocarboxypeptidase A2
Published in Archives of biochemistry and biophysics (01-08-1996)“…We are investigating the potential utility of human carboxypeptidases A in antibody-directed enzyme prodrug therapy (ADEPT). Hybridization screening of a human…”
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8
Fat cell β1-adrenergic receptor: structural evidence for existence of disulfide bridges essential for ligand binding
Published in Biochemistry (Easton) (01-10-1985)Get full text
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9
Changes in immunohistochemical properties of beta-adrenergic receptors in frog erythrocytes by isoproterenol-induced desensitization
Published in Life sciences (1973) (1988)“…Immunohistochemical properties of beta-adrenergic receptor (BAR) in frog erythrocytes have been studied by using antiserum raised against purified guinea pig…”
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