Search Results - "Moxham, Cary P."

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    Site-specific Conjugation on Serine → Cysteine Variant Monoclonal Antibodies by Stimmel, Julie B., Merrill, Barbara M., Kuyper, Lee F., Moxham, Cary P., Hutchins, Jeff T., Fling, Mary E., Kull, Frederick C.

    Published in The Journal of biological chemistry (29-09-2000)
    “…We have engineered a cysteine residue at position 442 (EU/OU numbering) in the third constant domain (CH3) of the heavy chain of several IgGs with different…”
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    Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate by Smith, G K, Banks, S, Blumenkopf, T A, Cory, M, Humphreys, J, Laethem, R M, Miller, J, Moxham, C P, Mullin, R, Ray, P H, Walton, L M, Wolfe, 3rd, L A

    Published in The Journal of biological chemistry (20-06-1997)
    “…Antibody-directed enzyme prodrug therapy (ADEPT) has the potential of greatly enhancing antitumor selectivity of cancer therapy by synthesizing…”
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    Insulin/IGF-I receptor hybrids: a mechanism for increasing receptor diversity by Moxham, C P, Jacobs, S

    Published in Journal of cellular biochemistry (01-02-1992)
    “…Insulin and IGF-I receptors are homologous disulfide linked alpha 2 beta 2 tetramers. These tetramers are formed biosynthetically when proreceptors containing…”
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  6. 6

    Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor by Yamamoto, K, Lapetina, E G, Moxham, C P

    Published in Endocrinology (Philadelphia) (01-03-1992)
    “…Stimulation by insulin-like growth factor-I (IGF-I) of LISN C4 cells, a mouse fibroblast cell line that overexpresses human IGF-I receptors, led to an increase…”
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  7. 7

    Expression and Characterization of Human Pancreatic Preprocarboxypeptidase A1 and Preprocarboxypeptidase A2 by Laethem, Ronald M., Blumenkopf, Todd A., Cory, Michael, Elwell, Lynn, Moxham, Cary P., Ray, Paul H., Walton, Leslie M., Smith, Gary K.

    Published in Archives of biochemistry and biophysics (01-08-1996)
    “…We are investigating the potential utility of human carboxypeptidases A in antibody-directed enzyme prodrug therapy (ADEPT). Hybridization screening of a human…”
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    Changes in immunohistochemical properties of beta-adrenergic receptors in frog erythrocytes by isoproterenol-induced desensitization by Alho, H, Dillion-Carter, O, Moxham, C P, Malbon, C C, Chuang, D M

    Published in Life sciences (1973) (1988)
    “…Immunohistochemical properties of beta-adrenergic receptor (BAR) in frog erythrocytes have been studied by using antiserum raised against purified guinea pig…”
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