Search Results - "Mowry, Bryan J."

Genetic influences on cost-efficient organization of human cortical functional networks by Fornito, Alex, Zalesky, Andrew, Bassett, Danielle S, Meunier, David, Ellison-Wright, Ian, Yücel, Murat, Wood, Stephen J, Shaw, Karen, O'Connor, Jennifer, Nertney, Deborah, Mowry, Bryan J, Pantelis, Christos, Bullmore, Edward T

“…The human cerebral cortex is a complex network of functionally specialized regions interconnected by axonal fibers, but the organizational principles…”
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Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications by Levinson, Douglas F., Duan, Jubao, Oh, Sang, Wang, Kai, Sanders, Alan R., Shi, Jianxin, Zhang, Nancy, Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Kendler, Kenneth S., Freedman, Robert, Dudbridge, Frank, Pe'er, Itsik, Hakonarson, Hakon, Bergen, Sarah E., Fanous, Ayman H., Holmans, Peter A., Gejman, Pablo V.

“…Objective:To evaluate previously reported associations of copy number variants (CNVs) with schizophrenia and to identify additional associations, the authors…”
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Genetic interactions of schizophrenia using gene-based statistical epistasis exclusively identify nervous system-related pathways and key hub genes by Periyasamy, Sathish, Youssef, Pierre, John, Sujit, Thara, Rangaswamy, Mowry, Bryan J

“…The relationship between genotype and phenotype is governed by numerous genetic interactions (GIs), and the mapping of GI networks is of interest for two main…”
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Interpreting the role of de novo protein-coding mutations in neuropsychiatric disease by Gratten, Jacob, Visscher, Peter M, Mowry, Bryan J, Wray, Naomi R

“…Jake Gratten and colleagues discuss challenges in interpreting the role of de novo mutations in neuropsychiatric and other complex diseases. They argue that…”
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Additive Genetic Variation in Schizophrenia Risk Is Shared by Populations of African and European Descent by de Candia, Teresa R., Lee, S. Hong, Yang, Jian, Browning, Brian L., Gejman, Pablo V., Levinson, Douglas F., Mowry, Bryan J., Hewitt, John K., Goddard, Michael E., O’Donovan, Michael C., Purcell, Shaun M., Posthuma, Danielle, Visscher, Peter M., Wray, Naomi R., Keller, Matthew C.

“…To investigate the extent to which the proportion of schizophrenia’s additive genetic variation tagged by SNPs is shared by populations of European and African…”
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Identification of sialyltransferase 8B as a generalized susceptibility gene for psychotic and mood disorders on chromosome 15q25-26 by McAuley, Erica Z, Scimone, Anna, Tiwari, Yash, Agahi, Giti, Mowry, Bryan J, Holliday, Elizabeth G, Donald, Jennifer A, Weickert, Cynthia Shannon, Mitchell, Phillip B, Schofield, Peter R, Fullerton, Janice M

“…We previously identified a significant bipolar spectrum disorder linkage peak on 15q25-26 using 35 extended families with a broad clinical phenotype, including…”
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Genome-Wide Association Study of Clinical Dimensions of Schizophrenia: Polygenic Effect on Disorganized Symptoms by Fanous, Ayman H., Zhou, Baiyu, Aggen, Steven H., Bergen, Sarah E., Amdur, Richard L., Duan, Jubao, Sanders, Alan R., Shi, Jianxin, Mowry, Bryan J., Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Dudbridge, Frank, Holmans, Peter A., Ripke, Stephan, Gejman, Pablo V., Kendler, Kenneth S., Levinson, Douglas F.

“…ObjectiveMultiple sources of evidence suggest that genetic factors influence variation in clinical features of schizophrenia. The authors present the first…”
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Immune dysregulation and self-reactivity in schizophrenia: Do some cases of schizophrenia have an autoimmune basis? by Jones, Amanda L, Mowry, Bryan J, Pender, Michael P, Greer, Judith M

“…Schizophrenia affects 1% of the world's population, but its cause remains obscure. Numerous theories have been proposed regarding the cause of schizophrenia,…”
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Common variants on chromosome 6p22.1 are associated with schizophrenia by Gejman, Pablo V, Shi, Jianxin, Levinson, Douglas F, Duan, Jubao, Sanders, Alan R, Zheng, Yonglan, Pe'er, Itsik, Dudbridge, Frank, Holmans, Peter A, Whittemore, Alice S, Mowry, Bryan J, Olincy, Ann, Amin, Farooq, Cloninger, C. Robert, Silverman, Jeremy M, Buccola, Nancy G, Byerley, William F, Black, Donald W, Crowe, Raymond R, Oksenberg, Jorge R, Mirel, Daniel B, Kendler, Kenneth S, Freedman, Robert

“…Schizophrenia, a devastating psychiatric disorder, has a prevalence of 0.5-1%, with high heritability (80-85%) and complex transmission. Recent studies…”
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Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study by Periyasamy, Sathish, John, Sujit, Padmavati, Raman, Rajendren, Preeti, Thirunavukkarasu, Priyadarshini, Gratten, Jacob, Vinkhuyzen, Anna, McRae, Allan, Holliday, Elizabeth G, Nyholt, Dale R, Nancarrow, Derek, Bakshi, Andrew, Hemani, Gibran, Nertney, Deborah, Smith, Heather, Filippich, Cheryl, Patel, Kalpana, Fowdar, Javed, McLean, Duncan, Tirupati, Srinivasan, Nagasundaram, Arunkumar, Gundugurti, Prasad Rao, Selvaraj, Krishnamurthy, Jegadeesan, Jayaprakash, Jorde, Lynn B, Wray, Naomi R, Brown, Matthew A, Suetani, Rachel, Giacomotto, Jean, Thara, Rangaswamy, Mowry, Bryan J

“…Genome-wide association studies (GWASs) in European populations have identified more than 100 schizophrenia-associated loci. A schizophrenia GWAS in a unique…”
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No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics by Sanders, Alan R., Duan, Jubao, Levinson, Douglas F., Shi, Jianxin, He, Deli, Hou, Cuiping, Burrell, Gregory J., Rice, John P., Nertney, Deborah A., Olincy, Ann, Rozic, Pablo, Vinogradov, Sophia, Buccola, Nancy G., Mowry, Bryan J., Freedman, Robert, Amin, Farooq, Black, Donald W., Silverman, Jeremy M., Byerley, William F., Crowe, Raymond R., Cloninger, C. Robert, Martinez, Maria, Gejman, Pablo V.

“…Objective: The authors carried out a genetic association study of 14 schizophrenia candidate genes ( RGS4, DISC1, DTNBP1, STX7, TAAR6, PPP3CC, NRG1, DRD2,…”
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Is there a role for antibodies targeting muscarinic acetylcholine receptors in the pathogenesis of schizophrenia? by Ryan, Alexander E, Mowry, Bryan J, Kesby, James P, Scott, James G, Greer, Judith M

“…Objective: Muscarinic receptor dysfunction has been suggested to play an important role in the pathophysiology of schizophrenia. Recently, it has also become…”
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Genome-Wide Association Study of Male Sexual Orientation by Sanders, Alan R., Beecham, Gary W., Guo, Shengru, Dawood, Khytam, Rieger, Gerulf, Badner, Judith A., Gershon, Elliot S., Krishnappa, Ritesha S., Kolundzija, Alana B., Duan, Jubao, Gejman, Pablo V., Bailey, J. Michael, Martin, Eden R.

“…Family and twin studies suggest that genes play a role in male sexual orientation. We conducted a genome-wide association study (GWAS) of male sexual…”
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Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium by Peterson, Roseann E., Bigdeli, Tim B., Ripke, Stephan, Bacanu, Silviu-Alin, Gejman, Pablo V., Levinson, Douglas F., Li, Qingqin S., Rujescu, Dan, Rietschel, Marcella, Weinberger, Daniel R., Straub, Richard E., Walters, James T.R., Owen, Michael J., O'Donovan, Michael C., Mowry, Bryan J., Ophoff, Roel A., Andreassen, Ole A., Esko, Tõnu, Petryshen, Tracey L., Kendler, Kenneth S., Fanous, Ayman H.

“…While 17% of US adults use tobacco regularly, smoking rates among persons with schizophrenia are upwards of 60%. Research supports a shared etiological basis…”
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Hybridization-based reconstruction of small non-coding RNA transcripts from deep sequencing data by Ragan, Chikako, Mowry, Bryan J, Bauer, Denis C

“…Recent advances in RNA sequencing technology (RNA-Seq) enables comprehensive profiling of RNAs by producing millions of short sequence reads from…”
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Fine-scaled human genetic structure revealed by SNP microarrays by Xing, Jinchuan, Watkins, W Scott, Witherspoon, David J, Zhang, Yuhua, Guthery, Stephen L, Thara, Rangaswamy, Mowry, Bryan J, Bulayeva, Kazima, Weiss, Robert B, Jorde, Lynn B

“…We report an analysis of more than 240,000 loci genotyped using the Affymetrix SNP microarray in 554 individuals from 27 worldwide populations in Africa, Asia,…”
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Elevated levels of autoantibodies targeting the M1 muscarinic acetylcholine receptor and neurofilament medium in sera from subgroups of patients with schizophrenia by Jones, Amanda L, Mowry, Bryan J, McLean, Duncan E, Mantzioris, Basil X, Pender, Michael P, Greer, Judith M

“…Abstract Schizophrenia is a severe debilitating brain disorder with a poorly understood aetiology. Among the diverse aetiological clues lies evidence for…”
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Genome-Wide Association Study of Multiplex Schizophrenia Pedigrees by Levinson, Douglas F., Shi, Jianxin, Wang, Kai, Oh, Sang, Riley, Brien, Pulver, Ann E., Wildenauer, Dieter B., Laurent, Claudine, Mowry, Bryan J., Gejman, Pablo V., Owen, Michael J., Kendler, Kenneth S., Nestadt, Gerald, Schwab, Sibylle G., Mallet, Jacques, Nertney, Deborah, Sanders, Alan R., Williams, Nigel M., Wormley, Brandon, Lasseter, Virginia K., Albus, Margot, Godard-Bauché, Stephanie, Alexander, Madeline, Duan, Jubao, O’Donovan, Michael C., Walsh, Dermot, O’Neill, Anthony, Papadimitriou, George N., Dikeos, Dimitris, Maier, Wolfgang, Lerer, Bernard, Campion, Dominique, Cohen, David, Jay, Maurice, Fanous, Ayman, Eichhammer, Peter, Silverman, Jeremy M., Norton, Nadine, Zhang, Nancy, Hakonarson, Hakon, Gao, Cynthia, Citri, Ami, Hansen, Mark, Ripke, Stephan, Dudbridge, Frank, Holmans, Peter A.

“…ObjectiveThe authors used a genome-wide association study (GWAS) of multiply affected families to investigate the association of schizophrenia to common…”
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Will Brain Cells Derived From Induced Pluripotent Stem Cells or Directly Converted From Somatic Cells (iNs) Be Useful for Schizophrenia Research? by FILIPPICH, Cheryl, WOLVETANG, Ernst J, MOWRY, Bryan J

“…The reprogramming of nonneuronal somatic cells to induced pluripotent stem cells and their derivation to functional brain cells as well as the related methods…”
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The Internet-Based MGS2 Control Sample: Self Report of Mental Illness by Sanders, Alan R., Levinson, Douglas F., Duan, Jubao, Dennis, J. Michael, Li, Rick, Kendler, Kenneth S., Rice, John P., Shi, Jianxin, Mowry, Bryan J., Amin, Farooq, Silverman, Jeremy M., Buccola, Nancy G., Byerley, William F., Black, Donald W., Freedman, Robert, Cloninger, C. Robert, Gejman, Pablo V.

“…ObjectiveThe Molecular Genetics of Schizophrenia (MGS2) project recruited an adult control sample of non-Hispanic European-ancestry (N=3,364) and African…”
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