Search Results - "Movsesian, M A"

Utility of long-term surveillance endomyocardial biopsy: a multi-institutional analysis by Stehlik, J, Starling, R C, Movsesian, M A, Fang, J C, Brown, R N, Hess, M L, Lewis, N P, Kirklin, J K

“…The utility of long-term endomyocardial biopsy surveillance in heart transplant recipients has been questioned. This study was undertaken to identify risk…”
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Beta-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors: shifting the focus from inotropy to cyclic adenosine monophosphate by Movsesian, Matthew A.

“…Clinical trials of beta-adrenergic receptor agonists and cyclic nucleotide phosphodiesterase inhibitors in heart failure have demonstrated a reduction in…”
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Identification of a novel isoform of the cyclic-nucleotide phosphodiesterase PDE3A expressed in vascular smooth-muscle myocytes by Choi, Y H, Ekholm, D, Krall, J, Ahmad, F, Degerman, E, Manganiello, V C, Movsesian, M A

“…We have identified a new cyclic-nucleotide phosphodiesterase isoform, PDE3A, and cloned its cDNA from cultured aortic myocytes. The nucleotide sequence of its…”
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Molecular Cloning and Expression of Human Myocardial cGMP-Inhibited cAMP Phosphodiesterase by Meacci, Elisabetta, Taira, Masato, Moos, Malcolm, Smith, Carolyn J., Movsesian, Matthew A., Degerman, Eva, Belfrage, per, Manganiello, Vincent

“…We have cloned a cDNA for a myocardial cGMP-inhibited cAMP phosphodiesterase (cGI PDE) from a human heart cDNA library in λ Zap II. The open reading frame [3.5…”
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Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling by Weninger, S., Van Craenenbroeck, K., Cameron, R.T., Vandeput, F., Movsesian, M.A., Baillie, G.S., Lefebvre, R.A.

“…Phosphodiesterase (PDE) 3 and PDE4, which degrade cyclic adenosine monophosphate (cAMP), are important regulators of 5-hydroxytryptamine (5-HT) 4 receptor…”
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Therapeutic potential of cyclic nucleotide phosphodiesterase inhibitors in heart failure by Movsesian, M A

“…There are several reasons to believe that agents that augment cAMP-mediated signalling in cardiac myocytes should have beneficial effects in patients with…”
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Pharmacologic and hemodynamic effects of combined beta-agonist stimulation and phosphodiesterase inhibition in the failing human heart by Gilbert, E M, Hershberger, R E, Wiechmann, R J, Movsesian, M A, Bristow, M R

“…We measured the individual and combined effects of the beta-agonist dobutamine and the phosphodiesterase inhibitor enoximone both in vitro and in vivo in the…”
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Phosphorylation of phospholamban by calcium-activated, phospholipid-dependent protein kinase. Stimulation of cardiac sarcoplasmic reticulum calcium uptake by Movsesian, M A, Nishikawa, M, Adelstein, R S

“…Ca2+-activated, phospholipid-dependent protein kinase (protein kinase C) is able to catalyze the phosphorylation of phospholamban in a canine cardiac…”
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Postpartum myocardial infarction by Movsesian, M A, Wray, R B

“…A 29 year old woman had a myocardial infarction three weeks post partum. Coronary angiography was performed six days later. No abnormalities were seen…”
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Sarcoplasmic reticulum-associated cyclic adenosine 5'-monophosphate phosphodiesterase activity in normal and failing human hearts by Movsesian, M A, Smith, C J, Krall, J, Bristow, M R, Manganiello, V C

“…Sarcoplasmic reticulum-associated cAMP phosphodiesterase activity was examined in microsomes prepared from the left ventricular myocardium of eight heart…”
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Effect of ryanodine on sarcoplasmic reticulum Ca2+ accumulation in nonfailing and failing human myocardium by NIMER, L. R, NEEDLEMAN, D. H, HAMILTON, S. L, KRALL, J, MOVSESIAN, M. A

“…The purpose of this study was to determine whether abnormal Ca2+ release through ryanodine-sensitive Ca2+ channels in the sarcoplasmic reticulum might…”
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Cytosolic and sarcoplasmic reticulum-associated low Km, cGMP-inhibited cAMP phosphodiesterase in mammalian myocardium by Smith, C J, Krall, J, Manganiello, V C, Movsesian, M A

“…The distribution and phosphoprotein band patterns of low Km, cGMP-inhibited cAMP phosphodiesterase (cGI PDE) activity were examined in cytosolic and microsomal…”
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Ca2+-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium by MOVSESIAN, M. A, KARIMI, M, GREEN, K, JONES, L. R

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Calcium uptake by sarcoplasmic reticulum and its modulation by cAMP-dependent phosphorylation in normal and failing human myocardium by Movsesian, M A

“…ATP-dependent, oxalate-supported Ca2+ uptake by cardiac sarcoplasmic reticulum was examined in microsomes prepared from left-ventricular free wall myocardium…”
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Ca(2+)-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium by Movsesian, M A, Karimi, M, Green, K, Jones, L R

“…Observations of abnormalities in the diastolic components of intracellular Ca2+ transients in failing human left ventricular myocardium have raised the…”
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Inhibitors of cyclic nucleotide phosphodiesterase PDE3 as adjunct therapy for dilated cardiomyopathy by Movsesian, Matthew A, Alharethi, Rami

“…PDE3 cyclic nucleotide phosphodiesterases are important in cyclic AMP (cAMP) and possibly cyclic GMP-mediated signalling in cardiac and vascular smooth muscle…”
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Calcium sequestration by the sarcoplasmic reticulum in heart failure by Movsesian, M A, Schwinger, R H

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Effects of Intracellular Acidosis on [Ca2+]i Transients, Transsarcolemmal Ca2+ Fluxes, and Contraction in Ventricular Myocytes by Kohmoto, Osami, Spitzer, Kenneth W, Movsesian, Matthew A, Barry, William H

“…We examined the effects of intracellular acidosis produced by washout of NH4Cl on [Ca]i transients (indo-1 fluorescence), cell contraction (video motion…”
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cAMP-Mediated Signal Transduction and Sarcoplasmic Reticulum Function in Heart Failure by MOVSESIAN, MATTHEW A.

“…There is evidence that the effects of β‐adrenergic receptor agonists on myocardial contractility result principally from the phosphorylation of phospholamban…”
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Identification and characterization of proteins in sarcoplasmic reticulum from normal and failing human left ventricles by Movsesian, M A, Leveille, C, Krall, J, Colyer, J, Wang, J H, Campbell, K P

“…Monoclonal and polyclonal antibodies to the major sarcoplasmic reticulum proteins of rabbit skeletal and canine cardiac muscle have been used to identify and…”
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