Non-invasive respiratory support in children and young adults with complex medical conditions in pediatric palliative care

ObjectiveDyspnoea and sleep-disordered breathing (SDB) are common in children with life-limiting conditions but studies on treatment with non-invasive ventilation (NIV) or continuous positive airway pressure (CPAP) are scarce. The aim of the study was to describe children treated with long-term NIV/...

Full description

Saved in:

Bibliographic Details
Published in:	Archives of disease in childhood Vol. 109; no. 11; pp. 918 - 923
Main Authors:	Fauroux, Brigitte, Taytard, Jessica, Ioan, Iulia, Lubrano, Marc, Le Clainche, Laurence, Bokov, Plamen, Dudoignon, Benjamin, Debelleix, Stephane, Galode, Francois, Coutier, Laurianne, Sigur, Elodie, Labouret, Geraldine, Ollivier, Morgane, Binoche, Alexandra, Bergougnioux, Jean, Mbieleu, Blaise, Essid, Aben, Hullo, Eglantine, Barzic, Audrey, Moreau, Johan, Jokic, Mikael, Denamur, Sophie, Aubertin, Guillaume, Schweitzer, Cyril, Becourt, Arnaud, Mouydi, Mariam, Ladaurade, Alice, Bui, Stéphanie, Cros, Pierrick, Labbé, Guillaume, Lampin, Marie Emilie, Mordacq, Clemence, Masson, Alexandra, Hangard, Pauline, Stremler, Nathalie, Baravalle-Einaudi, Melisande, Renoux, Marie Catherine, Matecki, Stefan, Fleurence, Emmanuelle, Fina, Agnes, Giovannini-Chami, Lisa, Khirani, Sonia, Griffon, Lucie, Diaz, Véronique, Pomedio, Michael, Heyman, Rachel, Gachelin, Elsa, Perisson, Caroline, Pervillé, Anne, Breining, Audrey, Genevois, Aline
Format:	Journal Article
Language:	English
Published:	England BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 12-07-2024 BMJ Publishing Group LTD BMJ Publishing Group
Subjects:	Anatomy Apnea Central nervous system Children Children & youth Continuous positive airway pressure Disease Dyspnea Families & family life Family (Sociological Unit) Gas exchange Hospitals Life Sciences Mechanical ventilation Medical Services National Surveys Nervous system Networks Neuromuscular diseases Original research Ostomy Outcome Measures Paediatrics Pain Palliation Palliative Care Patients Pediatrics Quality of life Questionnaires Respiration Respiratory Medicine Severe Disabilities Sleep Sleep disorders State Surveys Ventilation Young adults Italy Spain Palliative Care Pain Sleep Paediatrics Respiratory Medicine
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	ObjectiveDyspnoea and sleep-disordered breathing (SDB) are common in children with life-limiting conditions but studies on treatment with non-invasive ventilation (NIV) or continuous positive airway pressure (CPAP) are scarce. The aim of the study was to describe children treated with long-term NIV/CPAP within a paediatric palliative care programme in France.MethodsCross-sectional survey on children and young adults with complex medical conditions treated within the French paediatric NIV network with long-term NIV/CPAP. Characteristics of the patients were analysed and patient-related outcome measures of NIV/CPAP benefit were reported.ResultsThe data of 50 patients (68% boys), median age 12 (0.4–21) years were analysed. Twenty-three (46%) patients had a disorder of the central nervous system and 5 (10%) a chromosomal anomaly. Thirty-two (64%) patients were treated with NIV and 18 (36%) with CPAP. NIV/CPAP was initiated on an abnormal Apnoea-Hypopnoea Index in 18 (36%) of the patients, an abnormal nocturnal gas exchange alone in 28 (56%), and after an acute respiratory failure in 11 (22%) of the patients. Mean objective NIV/CPAP adherence was 9.3±3.7 hours/night. NIV/CPAP was associated with a decrease in dyspnoea in 60% of patients, an increase in sleep duration in 60% and in sleep quality in 74%, and an improvement in parents’ sleep in 40%.ConclusionsIn children with life-limiting conditions, long-term NIV/CPAP may be associated with relief of dyspnoea, an improvement of SDB and an improvement in parents’ sleep.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0003-9888 1468-2044 1468-2044
DOI:	10.1136/archdischild-2023-326782