Search Results - "Moutuou, Moutuaata M."

Restoring T Cell Homeostasis After Allogeneic Stem Cell Transplantation; Principal Limitations and Future Challenges by Moutuou, Moutuaata M, Pagé, Gabriel, Zaid, Intesar, Lesage, Sylvie, Guimond, Martin

“…For several leukemia patients, allogeneic stem cell transplantation (allogeneic-SCT) is the unique therapeutic modality that could potentially cure their…”
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Studying Peripheral T Cell Homeostasis in Mice: A Concise Technical Review by Moutuou, Moutuaata M, Gauthier, Simon-David, Chen, Nicolas, Leboeuf, Dominique, Guimond, Martin

“…For several years, it was believed that the thymus was entirely responsible for maintaining T cell homeostasis. Today, it is well-known that homeostatic…”
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Homeostatic cytokines in immune reconstitution and graft-versus-host disease by Thiant, Stéphanie, Moutuou, Moutuaata M., Leboeuf, Dominique, Guimond, Martin

“…•T cell reconstitution is impaired after allogeneic stem cell transplantation.•IL-7 and IL-15 in T cell homeostasis.•GVHD insult to stromal cells impairs…”
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Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions by Silvestri, Giovannino, Trotta, Rossana, Stramucci, Lorenzo, Ellis, Justin J, Harb, Jason G, Neviani, Paolo, Wang, Shuzhen, Eisfeld, Ann-Kathrin, Walker, Christopher J, Zhang, Bin, Srutova, Klara, Gambacorti-Passerini, Carlo, Pineda, Gabriel, Jamieson, Catriona H M, Stagno, Fabio, Vigneri, Paolo, Nteliopoulos, Georgios, May, Philippa C, Reid, Alistair G, Garzon, Ramiro, Roy, Denis-Claude, Moutuou, Moutuaata M, Guimond, Martin, Hokland, Peter, Deininger, Michael W, Fitzgerald, Garrett, Harman, Christopher, Dazzi, Francesco, Milojkovic, Dragana, Apperley, Jane F, Marcucci, Guido, Qi, Jianfei, Polakova, Katerina Machova, Zou, Ying, Fan, Xiaoxuan, Baer, Maria R, Calabretta, Bruno, Perrotti, Danilo

“…Persistence of drug-resistant quiescent leukemic stem cells (LSC) and impaired natural killer (NK) cell immune response account for relapse of chronic…”
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Modulating endothelial cells with EGFL7 to diminish aGVHD after allogeneic bone marrow transplantation in mice by Dorrance, Adrienne M., Moutuou, Moutuaata M., Goda, Chinmayee, Sell, Natalie E., Kalyan, Sonu, Karunasiri, Malith, Kulkarni, Rohan, Goulard, Marie, Kolovich, Sofia, Rudich, Alexander, Naumann, Eric, Ackaoui, Antoine, Bigras, Charles-Etienne, Daudelin, Francis, Garzon, Ramiro, Ranganathan, Parvathi, Guimond, Martin

“…Acute graft-versus-host disease (aGVHD) is the second most common cause of death after allogeneic hematopoietic stem cell transplantation (allo-HSCT),…”
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IL-7 Is the Limiting Homeostatic Factor that Constrains Homeostatic Proliferation of CD8+ T Cells after Allogeneic Stem Cell Transplantation and Graft-versus-Host Disease by Gauthier, Simon-David, Moutuou, Moutuaata M., Daudelin, Francis, Leboeuf, Dominique, Guimond, Martin

“…•CD8+ T cell reconstitution is impaired after allogeneic stem cell transplantation.•Low IL-7 concentrations constrain CD8+ T cell homeostatic…”
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Double-Negative T Cell Levels Correlate with Chronic Graft-versus-Host Disease Severity by Hillhouse, Erin E., Thiant, Stéphanie, Moutuou, Moutuaata M., Lombard-Vadnais, Félix, Parat, Rachel, Delisle, Jean-Sébastien, Ahmad, Imran, Roy, Denis-Claude, Guimond, Martin, Roy, Jean, Lesage, Sylvie

“…•Activated double-negative (DN) T cells are reduced at the onset of chronic graft-versus-host disease (cGVHD).•Low DN T cell proportion correlates with an…”
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Abstract 2675: A new dual-targeting anti-immune checkpoint therapeutic approach for the treatment of “hot” and “cold” tumors by Moutuou, Moutuaata M., DeLuce, Nora, Creton, Elodie, Lucchi, Honorine, Accolas, Julien, Savatier, Alexandra, Léonetti, Michel

“…Abstract Anti-Immune Checkpoint (ICP) antibody approaches provided a major breakthrough in the field of cancer therapy. However, their efficiency is mainly…”
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Persistence of Drug-Resistant Leukemic Stem Cells and Impaired NK Cell Immunity in CML Patients Depend on MIR300 Antiproliferative and PP2A-Activating Functions by Silvestri, Giovannino, Trotta, Rossana, Stramucci, Lorenzo, Ellis, Justin J., Harb, Jason G., Neviani, Paolo, Wang, Shuzhen, Eisfeld, Ann-Kathrin, Walker, Christopher J., Zhang, Bin, Srutova, Klara, Gambacorti-Passerini, Carlo, Pineda, Gabriel, Jamieson, Catriona H. M., Stagno, Fabio, Vigneri, Paolo, Nteliopoulos, Georgios, May, Philippa C., Reid, Alistair G., Garzon, Ramiro, Roy, Denis-Claude, Moutuou, Moutuaata M., Guimond, Martin, Hokland, Peter, Deininger, Michael W., Fitzgerald, Garrett, Harman, Christopher, Dazzi, Francesco, Milojkovic, Dragana, Apperley, Jane F., Marcucci, Guido, Qi, Jianfei, Polakova, Katerina Machova, Zou, Ying, Fan, Xiaoxuan, Baer, Maria R., Calabretta, Bruno, Perrotti, Danilo

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