Search Results - "Mouton, W."
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Current evidence on hospital antimicrobial stewardship objectives: a systematic review and meta-analysis
Published in The Lancet infectious diseases (01-07-2016)“…Summary Background Antimicrobial stewardship is advocated to improve the quality of antimicrobial use. We did a systematic review and meta-analysis to assess…”
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Invasive Aspergillosis by Aspergillus flavus : Epidemiology, Diagnosis, Antifungal Resistance, and Management
Published in Journal of fungi (Basel) (01-07-2019)“…is the second most common etiological agent of invasive aspergillosis (IA) after . However, most literature describes IA in relation to or together with other…”
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3
Clinical applications of population pharmacokinetic models of antibiotics: Challenges and perspectives
Published in Pharmacological research (01-08-2018)“…[Display omitted] Because of increasing antimicrobial resistance and the shortage of new antibiotics, there is a growing need to optimize the use of old and…”
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Combination therapy for carbapenem-resistant Gram-negative bacteria
Published in Journal of antimicrobial chemotherapy (01-09-2014)“…Carbapenem-resistant Gram-negative bacteria (CR-GNB) represent an increasing hazard in healthcare settings. A central question concerning the treatment of…”
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5
Resistance mechanisms and drug susceptibility testing of nontuberculous mycobacteria
Published in Drug resistance updates (01-06-2012)“…Abstract Nontuberculous mycobacteria (NTM) are increasingly recognized as causative agents of opportunistic infections in humans. For most NTM infections the…”
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6
Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
Published in The Lancet infectious diseases (01-06-2014)“…Summary Infections in critically ill patients are associated with persistently poor clinical outcomes. These patients have severely altered and variable…”
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Time-kill kinetics of antibiotics active against rapidly growing mycobacteria
Published in Journal of antimicrobial chemotherapy (01-03-2015)“…This study was conducted to generate basic pharmacodynamic information on the relationship between antibiotic concentrations and the growth of rapidly growing…”
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Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus
Published in The Lancet infectious diseases (01-02-2015)“…Summary In the face of diminishing therapeutic options for the treatment of infections caused by multidrug-resistant, Gram-negative bacteria, clinicians are…”
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Staphylococcus aureus internalization impairs osteoblastic activity and early differentiation process
Published in Scientific reports (03-09-2021)“…Staphylococcus aureus is the most frequent aetiology of bone and joint infections (BJI) and can cause relapsing and chronic infections. One of the main factors…”
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Multicentre validation of 4-well azole agar plates as a screening method for detection of clinically relevant azole-resistant Aspergillus fumigatus
Published in Journal of antimicrobial chemotherapy (01-12-2017)“…Azole-resistant Aspergillus fumigatus is emerging worldwide. Reference susceptibility testing methods are technically demanding and no validated commercial…”
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MIC-based dose adjustment: facts and fables
Published in Journal of antimicrobial chemotherapy (01-03-2018)“…Over recent decades, several publications have described optimization procedures for antibiotic therapy in the individual patient based on antimicrobial MIC…”
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Protein Binding: Do We Ever Learn?
Published in Antimicrobial Agents and Chemotherapy (01-07-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Optimal exposures of ceftazidime predict the probability of microbiological and clinical outcome in the treatment of nosocomial pneumonia
Published in Journal of antimicrobial chemotherapy (01-04-2013)“…The %fT>MIC of ceftazidime has been shown to correlate with microbiological outcome of Gram-negative bacteria (GNB) in preclinical studies. However, clinical…”
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Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?
Published in Journal of antimicrobial chemotherapy (01-10-2010)“…Background Gonorrhoea has been among the easiest infections to cure with antibiotics. Nevertheless, emerging resistance has driven repeated treatment shifts…”
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Temocillin (6 g daily) in critically ill patients: continuous infusion versus three times daily administration
Published in Journal of antimicrobial chemotherapy (01-03-2015)“…The growing incidence of infections caused by Enterobacteriaceae producing ESBLs has led to increased use of carbapenems. Temocillin, which resists most…”
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Consumption of antimicrobials in pigs, veal calves, and broilers in the Netherlands: quantitative results of nationwide collection of data in 2011
Published in PloS one (21-10-2013)“…In 2011, Dutch animal production sectors started recording veterinary antimicrobial consumption. These data are used by the Netherlands Veterinary Medicines…”
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Non-linear absorption pharmacokinetics of amoxicillin: consequences for dosing regimens and clinical breakpoints
Published in Journal of antimicrobial chemotherapy (01-10-2016)“…To describe the population pharmacokinetics of oral amoxicillin and to compare the PTA of current dosing regimens. Two groups, each with 14 healthy male…”
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In Vitro Antifungal Susceptibility Testing of Candida Isolates with the EUCAST Methodology, a New Method for ECOFF Determination
Published in Antimicrobial agents and chemotherapy (01-04-2017)“…The susceptibilities of 1,099 molecularly identified clinical isolates against 8 antifungal drugs were determined using the EUCAST microdilution method. A new…”
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The Pharmacokinetics and Pharmacodynamics of Pulmonary Mycobacterium avium Complex Disease Treatment
Published in American journal of respiratory and critical care medicine (15-09-2012)“…Currently recommended multidrug treatment regimens for Mycobacterium avium complex (MAC) lung disease yield limited cure rates. This results, in part, from…”
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A Novel Y319H Substitution in CYP51C Associated with Azole Resistance in Aspergillus flavus
Published in Antimicrobial agents and chemotherapy (01-10-2015)“…This study aimed to explore any mutation in the CYP51 gene conferring azole resistance in Aspergillus flavus. Two voriconazole-resistant and 45…”
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