Search Results - "Moustafa, Amal M."
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Synthesis of new quaternized chitosan Schiff bases and their N-alkyl derivatives as antimicrobial and anti-biofilm retardants in membrane technology
Published in International journal of biological macromolecules (01-05-2024)“…New quaternized salicylidene chitosan Schiff bases (QSCSBs) and their N-octyl derivatives (OQCs) have been synthesized and characterized, aiming to develop…”
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Design, synthesis, anti-inflammatory evaluation, and molecular modelling of new coumarin-based analogs combined curcumin and other heterocycles as potential TNF-α production inhibitors via upregulating Nrf2/HO-1, downregulating AKT/mTOR signalling pathways and downregulating NF-κB in LPS induced macrophages
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2023)“…Persistent inflammation contributes to various inflammatory conditions. Inflammation-related diseases may be treated by inhibiting pro-inflammatory mediators…”
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Synthesis and Cytotoxicity Against Human Breast Carcinoma Cell Evaluation of Some New 3,4-Disubstituted Coumarin Derivatives
Published in Pharmaceutical chemistry journal (2022)“…A novel series of 3,4-disubstitutued coumarin derivatives have been synthesized by the reaction of ethyl coumarin-3-carboxylate with pyrazole-3,5-dione and…”
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Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity
Published in Journal of enzyme inhibition and medicinal chemistry (01-12-2022)“…A new series of vinyl amide-, imidazolone-, and triazinone-linked combretastatin A-4 analogues have been designed and synthesised. These compounds have been…”
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α-glucosidase inhibitory anthranols, kenganthranols A-C, from the stem bark of Harungana madagascariensis
Published in Journal of natural products (Washington, D.C.) (01-02-2006)“…One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from…”
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Histological study of the role of CD34+ stem cells and mast cells in cyclophosphamide-induced thymic injury in rats and the possible attenuating role of melatonin
Published in Histochemistry and cell biology (01-06-2023)“…Cyclophosphamide (CP) is an anticancer drug that adversely affects immunity and thymus structure. Melatonin is a hormone secreted by the pineal gland. It…”
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Structural changes in testes of Streptozotocin induced diabetic rats and possible protective effect of royal jelly: light and electron microscopic study
Published in Ultrastructural pathology (02-01-2024)“…Diabetes mellitus (DM) is one of the most common metabolic diseases causing damage in many organs in the body including the testes. Royal Jelly (RJ) is one of…”
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The possible protective role of vitamin C versus melatonin on potassium dichromate induced changes in rat thyroid gland: light and electron microscopic study
Published in Ultrastructural pathology (04-03-2023)“…Potassium dichromate is widely used in various laboratory and industrial applications. Vitamin C and melatonin are well-known antioxidants. Study the…”
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Comparative study of the ameliorative effects of omega-3 versus selenium on etoposide-induced changes in Sertoli cells and ectoplasmic specialization of adult rat testes: immunohistochemical and electron microscopic study
Published in Journal of molecular histology (01-06-2022)“…Etoposide (Eto) is an anti-cancer drug that is associated with serious adverse effects on male reproductive function. Omega-3 polyunsaturated fatty acids (ω-3…”
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Growth hormone enhances the CD34+ stem cells repopulation of the male albino rat thymus gland in cyclophosphamide induced injury: immunohistochemical and electron microscopic study
Published in Ultrastructural pathology (04-03-2023)“…Cyclophosphamide (CP) is a chemotherapeutic drug that has a harmful effect on the immune system. Growth hormone (GH) is a peptide hormone that can enhance…”
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Design, Synthesis, and Anti-Breast Cancer Activity of Some Hybrid Molecules Containing Coumarin Moiety
Published in Russian journal of bioorganic chemistry (2021)“…(Benzimidazol-2-yl)-7-hydroxycoumarin and N -(2-hydroxyphenyl)-7-hydroxycoumarin-3-carboxamide have been synthesized by the condensation of ethyl…”
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Effect of preischemic treatment with fenofibrate, a peroxisome proliferator-activated receptor-α ligand, on hepatic ischemia-reperfusion injury in rats
Published in Journal of molecular histology (01-04-2011)“…Liver ischemia/reperfusion (I/R) injury is a serious clinical problem. The reactive oxygen species (ROS) and tumor necrosis factor alpha (TNF-α) are important…”
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The possible role of L-carnitine on the skeletal muscle of ovariectomized rats
Published in Journal of molecular histology (01-06-2011)“…Low muscle strength is observed during the peri-and postmenopausal periods, when the secretion of ovarian hormones is drastically reduced. It is also a…”
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Potato disc bioassay and cytotoxic effect of Leptadenia pyrotechnica: comparative study of diverse extracts
Published in Pakistan journal of biological sciences (15-09-2011)“…Comparative acute toxicity studies of the latex and sequential extracts of Leptadenia pyrotechnica (Forsk.) Decne (Asclepiadaceae) were recorded using brine…”
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α-Glucosidase Inhibitory Anthranols, Kenganthranols A−C, from the Stem Bark of Harungana m adagascariensis
Published in Journal of natural products (Washington, D.C.) (24-02-2006)“…One new prenylated 1,4-anthraquinone and three new prenylated anthranols, named kengaquinone (1) and kenganthranols A (2), B (3), and C (4), were isolated from…”
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RETRACTED ARTICLE: Effect of preischemic treatment with fenofibrate, a peroxisome proliferator-activated receptor-α ligand, on hepatic ischemia–reperfusion injury in rats
Published in Journal of molecular histology (01-04-2011)“…Liver ischemia/reperfusion (I/R) injury is a serious clinical problem. The reactive oxygen species (ROS) and tumor necrosis factor alpha (TNF-α) are important…”
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Journal Article -
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RETRACTED ARTICLE: Effect of preischemic treatment with fenofibrate, a peroxisome proliferator-activated receptor-[alpha] ligand, on hepatic ischemia-reperfusion injury in rats
Published in Journal of molecular histology (01-04-2011)“…Liver ischemia/reperfusion (I/R) injury is a serious clinical problem. The reactive oxygen species (ROS) and tumor necrosis factor alpha (TNF-[alpha]) are…”
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Phytochemical Investigation and Toxicological Studies of Lipid Constituents Isolated from Leptadenia pyrotechnica
Published in Journal of pharmacology & toxicology (01-11-2007)“…Investigation of the chemical constituents of Leptadenia pyrotechnica (Asclepiadaceace family) let to isolate three terpenes; phytol, squalene and taraxerol,…”
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