Search Results - "Mousavizadeh, Rouhollah"

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  1. 1

    β1 integrin, ILK and mTOR regulate collagen synthesis in mechanically loaded tendon cells by Mousavizadeh, Rouhollah, Hojabrpour, Payman, Eltit, Felipe, McDonald, Paul C., Dedhar, Shoukat, McCormack, Robert G., Duronio, Vincent, Jafarnejad, Seyed Mehdi, Scott, Alex

    Published in Scientific reports (28-07-2020)
    “…Tendons are specialized tissues composed primarily of load-responsive fibroblasts (tenocytes) embedded in a collagen-rich extracellular matrix. Habitual…”
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    Journal Article
  2. 2

    MRGPRX2-mediated mast cell activation by substance P from overloaded human tenocytes induces inflammatory and degenerative responses in tendons by Mousavizadeh, Rouhollah, Waugh, Charlie M., McCormack, Robert G., Cairns, Brian E., Scott, Alex

    Published in Scientific reports (12-06-2024)
    “…Mast cells are immune cells minimally present in normal tendon tissue. The increased abundance of mast cells in tendinopathy biopsies and at the sites of…”
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    Journal Article
  3. 3

    Exposure to oxLDL impairs TGF-β activity in human tendon cells by Mousavizadeh, Rouhollah, Waugh, Charlie M, DeBruin, Erin, McCormack, Robert G, Duronio, Vincent, Scott, Alex

    Published in BMC musculoskeletal disorders (16-03-2023)
    “…Previous studies have shown that patients with hypercholesterolemia experience elevated levels of oxidized LDL (oxLDL), a molecule which triggers inflammation…”
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    Journal Article
  4. 4

    The application of mechanical load onto mouse tendons by magnetic restraining represses Mmp-3 expression by Mousavizadeh, Rouhollah, West, Valerie C, Inguito, Kameron L, Elliott, Dawn M, Parreno, Justin

    Published in BMC research notes (30-06-2023)
    “…Mechanical loading is crucial for tendon matrix homeostasis. Under-stimulation of tendon tissue promotes matrix degradation and ultimately tendon failure. In…”
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    Journal Article
  5. 5

    Mild hypercholesterolemia impacts achilles sub-tendon mechanical properties in young rats by Waugh, Charlie M, Mousavizadeh, Rouhollah, Lee, Jenny, Screen, Hazel R C, Scott, Alexander

    Published in BMC musculoskeletal disorders (12-04-2023)
    “…Hypercholesterolemia is associated with tendon pathology, but the reasons underpinning this relationship are not well understood. Cholesterol can accumulate in…”
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    Journal Article
  6. 6

    Cyclic strain alters the expression and release of angiogenic factors by human tendon cells by Mousavizadeh, Rouhollah, Khosravi, Shahram, Behzad, Hayedeh, McCormack, Robert G, Duronio, Vincent, Scott, Alex

    Published in PloS one (13-05-2014)
    “…Angiogenesis is associated with the tissue changes underlying chronic overuse tendinopathy. We hypothesized that repetitive, cyclic loading of human tendon…”
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    Journal Article
  7. 7

    The Impact of Hypercholesterolemia on Tendon Injury Repair by Waugh, Charlie, Mousavizadeh, Rouhollah, Screen, Hazel, Scott, Alexander

    Published in The FASEB journal (01-05-2021)
    “…Background Hypercholesterolemia is a condition characterized by high blood cholesterol levels and is associated with tendon xanthomas (cholesterol deposits…”
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    Journal Article
  8. 8

    In vitro collagen biomarkers in mechanically stimulated human tendon cells: a systematic review by Squier, Kipling, Mousavizadeh, Rouhollah, Damji, Faraz, Beck, Charlotte, Hunt, Michael, Scott, Alexander

    Published in Connective tissue research (03-03-2024)
    “…The aim of this study was to comprehensively examine and summarize the available in vitro evidence regarding the relationship between mechanical stimulation…”
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    Journal Article
  9. 9

    Exposure to oxLDL impairs TGF-[beta] activity in human tendon cells by Mousavizadeh, Rouhollah, Waugh, Charlie M, DeBruin, Erin, McCormack, Robert G, Duronio, Vincent, Scott, Alex

    Published in BMC musculoskeletal disorders (16-03-2023)
    “…Background Previous studies have shown that patients with hypercholesterolemia experience elevated levels of oxidized LDL (oxLDL), a molecule which triggers…”
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    Journal Article
  10. 10

    Mast cells exert pro-inflammatory effects of relevance to the pathophyisology of tendinopathy by Behzad, Hayedeh, Sharma, Aishwariya, Mousavizadeh, Rouhollah, Lu, Alex, Scott, Alex

    Published in Arthritis research & therapy (01-01-2013)
    “…We have previously found an increased mast cell density in tendon biopsies from patients with patellar tendinopathy compared to controls. This study examined…”
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    Journal Article
  11. 11

    The impact of mild hypercholesterolemia on injury repair in the rat patellar tendon by Waugh, Charlie M., Mousavizadeh, Rouhollah, Lee, Jenny, Screen, Hazel R. C., Scott, Alexander

    Published in Journal of orthopaedic research (01-09-2023)
    “…Hypercholesterolemia is associated with tendon pathology and injury prevalence. Lipids can accumulate in the tendon's extracellular spaces, which may disrupt…”
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    Journal Article
  12. 12

    The tourniquet's effects on skeletal muscle during total knee arthroplasty by Johnsen, Magnus, Mousavizadeh, Rouhollah, Scott, Alex, Havik, Steinar, Husby, Vigdis S., Winther, Siri B., Husby, Otto S., Lian, Øystein

    Published in Journal of orthopaedic research (01-09-2024)
    “…This study investigates the impact of perioperative tourniquet on skeletal muscle cells during total knee arthroplasty (TKA) and its effects on the gene…”
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    Journal Article
  13. 13

    Influence of repetitive mechanical loading on MMP2 activity in tendon fibroblasts by Huisman, Elise, Lu, Alex, Jamil, Sarwat, Mousavizadeh, Rouhollah, McCormack, Robert, Roberts, Clive, Scott, Alex

    Published in Journal of orthopaedic research (01-11-2016)
    “…ABSTRACT Matrix metalloproteinase2 has been implicated in tendon pathology caused by repetitive movements. However, its activity in the early stages of the…”
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    Journal Article
  14. 14

    Angiopoietin-like 4 Enhances the Proliferation and Migration of Tendon Fibroblasts by JAMIL, SARWAT, MOUSAVIZADEH, ROUHOLLAH, ROSHAN-MONIRI, MANI, TEBBUTT, SCOTT J, MCCORMACK, ROBERT G, DURONIO, VINCENT, SCOTT, ALEX

    “…PURPOSEAngiopoietin-like 4 (ANGPTL4) is known to play a variety of roles in the response to exercise, and more recently has been shown to enhance the healing…”
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    Journal Article
  15. 15

    Angiopoietin‐like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblasts by Mousavizadeh, Rouhollah, Scott, Alex, Lu, Alex, Ardekani, Gholamreza S, Behzad, Hayedeh, Lundgreen, Kirsten, Ghaffari, Mazyar, McCormack, Robert G, Duronio, Vincent

    Published in The Journal of physiology (01-06-2016)
    “…Key points Angiopoietin‐like 4 (ANGPTL4) modulates tendon neovascularization. Cyclic loading stimulates the activity of transforming growth factor‐β and…”
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    Journal Article
  16. 16

    Abstract B013: STEAP1 facilitates iron transport in ewing sarcoma to support mitochondrial activity by Shyp, Taras, Mousavizadeh, Rouhollah, Negri, Gian Luca, Zhang, Hai-Feng, Lizardo, Michael, Sorensen, Poul

    Published in Clinical cancer research (15-09-2022)
    “…Abstract Ewing sarcoma (EwS) is a highly aggressive bone-associated tumor of children and young adults with strong propensity to progress and dismal outcome…”
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    Journal Article
  17. 17

    Effect of Spiritual Care Program on Quality of Life in Patients with Heart Failure by farideh movahedi, Nasim Naderi, Fidan Shabani, Sepideh Taghavi, Rouhollah Mousavizadeh, Mahmood Sheikh Fathollahi

    “…Background: Heart failure (HF) is the common result of most heart disorders. The quality of life (QoL) of these patients is severely impaired and they need…”
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    Journal Article
  18. 18

    Dexamethasone decreases substance P expression in human tendon cells: an in vitro study by Mousavizadeh, Rouhollah, Backman, Ludvig, McCormack, Robert G, Scott, Alex

    Published in Rheumatology (Oxford, England) (01-02-2015)
    “…Glucocorticoid injections are used by rheumatologists to treat chronic tendinopathy. Surprisingly, the mechanisms by which corticosteroids induce pain relief…”
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    Journal Article
  19. 19

    Mechanism of mast cell adhesion to human tenocytes in vitro by Behzad, Hayedeh, Tsai, Shu-Huei, Nassab, Paulina, Mousavizadeh, Rouhollah, McCormack, Robert G., Scott, Alex

    Published in Journal of orthopaedic research (01-01-2015)
    “…ABSTRACT Mast cells and fibroblasts are two key players involved in many fibrotic and degenerative disorders. In the present study we examined the nature of…”
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    Journal Article
  20. 20