Search Results - "Mousa, Shaaban"

CXCL10 controls inflammatory pain via opioid peptide-containing macrophages in electroacupuncture by Wang, Ying, Gehringer, Rebekka, Mousa, Shaaban A, Hackel, Dagmar, Brack, Alexander, Rittner, Heike L

“…Acupuncture is widely used for pain treatment in patients with osteoarthritis or low back pain, but molecular mechanisms remain largely enigmatic. In the early…”
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Pro- versus Antinociceptive Nongenomic Effects of Neuronal Mineralocorticoid versus Glucocorticoid Receptors during Rat Hind Paw Inflammation by Li, Xiongjuan, Shaqura, Mohammed, Mohamed, Doaa, Beyer, Antje, Yamada, Shunji, Mousa, Shaaban A, Schäfer, Michael

“…BACKGROUND:In naive rats, corticosteroids activate neuronal membrane–bound glucocorticoid and mineralocorticoid receptors in spinal cord and periphery to…”
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Pathological alterations in liver injury following congestive heart failure induced by volume overload in rats by Shaqura, Mohammed, Mohamed, Doaa M, Aboryag, Noureddin B, Bedewi, Lama, Dehe, Lukas, Treskatsch, Sascha, Shakibaei, Mehdi, Schäfer, Michael, Mousa, Shaaban A

“…Heart failure has emerged as a disease with significant public health implications. Following progression of heart failure, heart and liver dysfunction are…”
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Aldosterone Synthase in Peripheral Sensory Neurons Contributes to Mechanical Hypersensitivity during Local Inflammation in Rats by Mohamed, Doaa M., Shaqura, Mohammed, Li, Xiongjuan, Shakibaei, Mehdi, Beyer, Antje, Treskatsch, Sascha, Schäfer, Michael, Mousa, Shaaban A.

“…BACKGROUND:Recent emerging evidence suggests that extra-adrenal synthesis of aldosterone occurs (e.g., within the failing heart and in certain brain areas). In…”
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Membrane-bound glucocorticoid receptors on distinct nociceptive neurons as potential targets for pain control through rapid non-genomic effects by Shaqura, Mohammed, Li, Xiongjuan, Al-Khrasani, Mahmoud, Shakibaei, Mehdi, Tafelski, Sascha, Fürst, Susanna, Beyer, Antje, Kawata, Mitsuhiro, Schäfer, Michael, Mousa, Shaaban A.

“…Glucocorticoids were long believed to primarily function through cytosolic glucocorticoid receptor (GR) activation and subsequent classical genomic pathways…”
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Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain areas by Mousa, Shaaban A, Khalefa, Baled I, Shaqura, Mohammed, Al-Madol, Mohammed, Treskatsch, Sascha, Schäfer, Michael

“…Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release…”
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Immune cell-derived opioids protect against neuropathic pain in mice by Labuz, Dominika, Schmidt, Yvonne, Schreiter, Anja, Rittner, Heike L, Mousa, Shaaban A, Machelska, Halina

“…The analgesic effects of leukocyte-derived opioids have been exclusively demonstrated for somatic inflammatory pain, for example, the pain associated with…”
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Naltrexone-Induced Cardiac Function Improvement is Associated With an Attenuated Inflammatory Response and Lipid Perioxidation in Volume Overloaded Rats by Dehe, Lukas, Mousa, Shaaban A., Shaqura, Mohammed, Shakibaei, Mehdi, Schäfer, Michael, Treskatsch, Sascha

“…In previous studies, upregulation of myocardial opioid receptors as well as the precursors of their endogenous ligands were detected in the failing heart due…”
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The presence of mu-, delta-, and kappa-opioid receptors in human heart tissue by Sobanski, Piotr, Krajnik, Malgorzata, Shaqura, Mohammed, Bloch-Boguslawska, Elzbieta, Schäfer, Michael, Mousa, Shaaban A.

“…Functional evidence suggests that the stimulation of peripheral and central opioid receptors (ORs) is able to modulate heart function. Moreover, selective…”
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Identification of glucocorticoid receptors as potential modulators of parasympathetic and sympathetic neurons within rat intracardiac ganglia by Mousa, Shaaban A, Dehe, Lukas, Aboryag, Noureddin, Shaqura, Mohammed, Beyer, Antje, Schäfer, Michael, Treskatsch, Sascha

“…Emerging evidences indicate that glucocorticoid receptors (GR) play a regulatory role in cardiac function, particularly with regard to the autonomic nervous…”
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Identification of mineralocorticoid and glucocorticoid receptors on peripheral nociceptors: Translation of experimental findings from animal to human biology by Tafelski, Sascha, Mohamed, Doaa, Shaqura, Mohammed, Assaf, Chalid, Beyer, Antje, Treskatsch, Sascha, Schäfer, Michael, Mousa, Shaaban A.

“…•Neuronal MR und GR receptors modulate pain by genomic and non-genomic mechanisms.•Translation of findings in animal models was focussed in this study.•MR and…”
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Toll like Receptor (TLR)-4 as a Regulator of Peripheral Endogenous Opioid-Mediated Analgesia in Inflammation by Sauer, Reine-Solange, Hackel, Dagmar, Morschel, Laura, Sahlbach, Henrike, Wang, Ying, Mousa, Shaaban A, Roewer, Norbert, Brack, Alexander, Rittner, Heike L

“…Background: Leukocytes containing opioid peptides locally control inflammatory pain. In the early phase of complete Freund's adjuvant (CFA)-induced hind paw…”
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Accessibility of axonal G protein coupled mu-opioid receptors requires conceptual changes of axonal membrane targeting for pain modulation by Mousa, Shaaban A., Shaqura, Mohammed, Al-Madol, Mohammed, Tafelski, Sascha, Khalefa, Baled I., Shakibaei, Mehdi, Schäfer, Michael

“…The mechanisms of axonal trafficking and membrane targeting are well established for sodium channels, which are the principle targets for perineurally applied…”
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Translation of Experimental Findings from Animal to Human Biology: Identification of Neuronal Mineralocorticoid and Glucocorticoid Receptors in a Sectioned Main Nerve Trunk of the Leg by Tafelski, Sascha, Wandrey, Jan D, Shaqura, Mohammed, Hong, Xueqi, Beyer, Antje, Schäfer, Michael, Mousa, Shaaban A

“…The activation of the mineralocorticoid (MR) and glucocorticoid (GR) receptors on peripheral sensory neurons seems to modify pain perception through both…”
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Functional and Anatomical Characterization of Corticotropin-Releasing Factor Receptor Subtypes of the Rat Spinal Cord Involved in Somatic Pain Relief by Mousa, Shaaban A., Shaqura, Mohammed, Khalefa, Baled I., Li, Li, Al-Madol, Mohammed, Treskatsch, Sascha, Schäfer, Michael

“…Corticotropin-releasing factor (CRF) orchestrates our body’s response to stressful stimuli. Pain is often stressful and counterbalanced by activation of CRF…”
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A modified approach to induce predictable congestive heart failure by volume overload in rats by Treskatsch, Sascha, Feldheiser, Aarne, Rosin, Adrian T, Sifringer, Marco, Habazettl, Helmut, Mousa, Shaaban A, Shakibaei, Mehdi, Schäfer, Michael, Spies, Claudia D

“…The model of infrarenal aortocaval fistula (ACF) has recently gained new interest in its use to investigate cardiac pathophysiology. Since in previous…”
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Identification of Mineralocorticoid Receptors, Aldosterone, and Its Processing Enzyme CYP11B2 on Parasympathetic and Sympathetic Neurons in Rat Intracardiac Ganglia by Dehe, Lukas, Mousa, Shaaban A, Aboryag, Noureddin, Shaqura, Mohammed, Beyer, Antje, Schäfer, Michael, Treskatsch, Sascha

“…Recent interest has focused on the mineralocorticoid receptor (MR) and its impact on the myocardium and the performance of the heart. However, there is a lack…”
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Neuronal aldosterone elicits a distinct genomic response in pain signaling molecules contributing to inflammatory pain by Shaqura, Mohammed, Li, Li, Mohamed, Doaa M, Li, Xiongjuan, Treskatsch, Sascha, Buhrmann, Constanze, Shakibaei, Mehdi, Beyer, Antje, Mousa, Shaaban A, Schäfer, Michael

“…Recently, mineralocorticoid receptors (MR) were identified in peripheral nociceptive neurons, and their acute antagonism was responsible for immediate and…”
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Acute mechanical sensitization of peripheral nociceptors by aldosterone through non-genomic activation of membrane bound mineralocorticoid receptors in naive rats by Shaqura, Mohammed, Li, Xiongjuan, Al-Madol, Mohammed A., Tafelski, Sascha, Beyer-Koczorek, Antje, Mousa, Shaaban A., Schäfer, Michael

“…Recently, there is increasing interest in the role of peripheral mineralocorticoid receptors (MR) to modulate pain, but their localization in neurons and glia…”
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Protein kinase C-mediated mu-opioid receptor phosphorylation and desensitization in rats, and its prevention during early diabetes by Mousa, Shaaban A., Shaqura, Mohammed, Winkler, Jens, Khalefa, Baled I., Al-Madol, Mohammed A., Shakibaei, Mehdi, Schulz, Stefan, Schäfer, Michael

“…Painful diabetic neuropathy is associated with impaired opioid analgesia; however, the precise mechanism in sensory neurons remains unclear. This study aimed…”
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