Search Results - "Mourik, Niels"
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Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study
Published in PloS one (30-10-2019)“…Acute respiratory distress syndrome (ARDS) is characterized by acute, diffuse, inflammatory lung injury leading to increased pulmonary vascular permeability,…”
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Risk of Aerosol Formation During High-Flow Nasal Cannula Treatment in Critically Ill Subjects
Published in Respiratory care (01-06-2021)“…There is a persistent concern over the risk of respiratory pathogen transmission, including SARS-CoV-2, via the formation of aerosols (ie, a suspension of…”
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Aged versus fresh autologous platelet transfusion in a two‐hit healthy volunteer model of transfusion‐related acute lung injury
Published in Transfusion (Philadelphia, Pa.) (01-12-2022)“…Background Transfusion‐related acute lung injury (TRALI) is a severe complication of blood transfusion that is thought of as a two‐hit event: first the…”
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Intramuscular adipose tissue at level Th12 is associated with survival in COVID‐19
Published in Journal of cachexia, sarcopenia and muscle (01-06-2021)“…Sarcopenia, as an example of abnormal body composition, is defined as a significant loss of skeletal muscle mass (muscle wasting) and muscle strength and…”
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Incidence of transfusion‐related acute lung injury temporally associated with solvent/detergent plasma use in the ICU: A retrospective before and after implementation study
Published in Transfusion (Philadelphia, Pa.) (01-09-2022)“…Background Transfusion‐related acute lung injury (TRALI) is a severe complication of plasma transfusion, though the use of solvent/detergent pooled plasma…”
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Towards personalized medicine: a scoping review of immunotherapy in sepsis
Published in Critical care (London, England) (28-05-2024)“…Despite significant progress in our understanding of the pathophysiology of sepsis and extensive clinical research, there are few proven therapies addressing…”
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25-Hydroxyvitamin D concentrations do not affect the humoral or cellular immune response following SARS-CoV-2 mRNA vaccinations
Published in Vaccine (07-03-2024)“…•BNT162b2 or mRNA-1273 induced antibodies are not affected by 25(OH)D concentration.•BNT162b2 induced T cell responses are not associated with 25(OH)D…”
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The predictive value of the modified early warning score for admission to the intensive care unit in patients with a hematologic malignancy – A multicenter observational study
Published in Intensive & critical care nursing (01-12-2023)“…The modified early warning score (MEWS) is used to detect clinical deterioration of hospitalized patients. We aimed to investigate the predictive value of MEWS…”
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The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees
Published in EBioMedicine (01-01-2023)“…Afucosylated IgG1 responses have only been found against membrane-embedded epitopes, including anti-S in SARS-CoV-2 infections. These responses, intrinsically…”
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Personalised immunotherapy in sepsis: a scoping review protocol
Published in BMJ open (09-05-2022)“…IntroductionSepsis, a life-threatening organ dysfunction syndrome occurring in the context of severe infections, remains a major burden on global health with…”
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The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccineesResearch in context
Published in EBioMedicine (01-01-2023)“…Background: Afucosylated IgG1 responses have only been found against membrane-embedded epitopes, including anti-S in SARS-CoV-2 infections. These responses,…”
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A Higher Fluid Balance in the Days After Septic Shock Reversal Is Associated With Increased Mortality: An Observational Cohort Study
Published in Critical care explorations (01-10-2020)“…Previous studies demonstrated that extensive fluid loading and consequently positive fluid balances during sepsis resuscitation are associated with adverse…”
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Mapping the human genetic architecture of COVID-19
Published in Nature (London) (16-12-2021)“…The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors…”
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Afucosylated IgG characterizes enveloped viral responses and correlates with COVID-19 severity
Published in Science (American Association for the Advancement of Science) (26-02-2021)“…Immunoglobulin G (IgG) antibodies are crucial for protection against invading pathogens. A highly conserved N-linked glycan within the IgG-Fc tail, which is…”
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Autoantibodies against type I interferons are associated with multi-organ failure in COVID-19 patients
Published in Intensive care medicine (01-06-2021)Get full text
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Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study
Published in The lancet respiratory medicine (01-02-2021)“…Little is known about the practice of ventilation management in patients with COVID-19. We aimed to describe the practice of ventilation management and to…”
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Hypotension during intensive care stay and mortality and morbidity: a systematic review and meta-analysis
Published in Intensive care medicine (01-04-2024)“…Purpose The aim of this study is to provide a summary of the existing literature on the association between hypotension during intensive care unit (ICU) stay…”
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Lung Microbiota of Critically Ill Patients with COVID-19 Are Associated with Nonresolving Acute Respiratory Distress Syndrome
Published in American journal of respiratory and critical care medicine (01-10-2022)“…Bacterial lung microbiota are correlated with lung inflammation and acute respiratory distress syndrome (ARDS) and altered in severe coronavirus disease…”
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ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol
Published in BMJ open (20-12-2022)“…Sepsis is a major cause of death among hospitalised patients. Accumulating evidence suggests that immune response during sepsis cascade lies within a spectrum…”
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Clinical features and prognostic factors in Covid-19: A prospective cohort study
Published in EBioMedicine (01-05-2021)“…Mortality rates are high among hospitalized patients with COVID-19, especially in those intubated on the ICU. Insight in pathways associated with unfavourable…”
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