Search Results - "Mourich, D"

Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing by Marshall, N.B., Oda, S.K., London, C.A., Moulton, H.M., Iversen, P.L., Kerkvliet, N.I., Mourich, D.V.

“…Phosphorodiamidate morpholino oligomers (PMO) are synthetic antisense molecules that interfere with translation, pre-mRNA splicing and RNA synthesis. Like…”
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Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function by Morse, M A, Hobeika, A, Serra, D, Aird, K, McKinney, M, Aldrich, A, Clay, T, Mourich, D, Lyerly, H K, Iversen, P L, Devi, G R

“…CD4+CD25+regulatory T cells (T reg ) impair anti-tumor and anti-viral immunity. As there are higher T reg levels in cancer patients compared with healthy…”
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Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers by Alonso, M, Stein, D A, Thomann, E, Moulton, H M, Leong, J C, Iversen, P, Mourich, D V

“…Delivery of phosphorodiamidate morpholino oligomers (PMO) into fish cells in vitro and tissues in vivo was examined. Uptake was evaluated by fluorescence…”
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4‐1BB and OX40 stimulation enhance CD8 and CD4 T‐cell responses to a DNA prime, poxvirus boost vaccine by Munks, Michael W., Mourich, Dan V., Mittler, Robert S., Weinberg, Andrew D., Hill, Ann B.

“…Summary 4‐1BB (CD137) is a tumour necrosis factor receptor (TNFR) family member, expressed primarily on CD8 T cells after activation. Signalling through 4‐1BB…”
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Human Herpesvirus 8 Detection in Nasal Secretions and Saliva by Blackbourn, David J., Lennette, Evelyne T., Ambroziak, John, Mourich, Dan V., Levy, Jay A.

“…The presence of human herpesvirus 8 (HHV-8) was determined by polymerase chain reaction (PCR) in nasal secretions and saliva from 14 HHV-8-seropositive…”
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Antisense approaches to immune modulation for transplant and autoimmune diseases by Mourich, Dan V, Marshall, Nikki B

“…Antisense oligomers have been shown to be effective tools for inhibiting gene expression in a highly specific manner. This technology has proven to be…”
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Spermine compaction is an efficient and economical method of producing vaccination-grade DNA by Mourich, Dan V., Munks, Michael W., Murphy, Jason C., Willson, Richard C., Hill, Ann B.

“…Plasmid DNA inoculations can induce both humoral and cellular immunity, and this technique is now being employed in developing vaccination regimens for a large…”
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Lack of differences in nef alleles among HIV-infected asymptomatic long-term survivors and those who progressed to disease by Mourich, D V, Lee, S, Reyes-Teran, G, Mackewicz, C E, Levy, J A

“…Sequences of the human immunodeficiency virus (HIV) nef gene in virus isolates from 12 long-term survivors (LTSs) and 7 progressors were compared to determine…”
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Epitope mapping and characterization of the infectious hematopoietic necrosis virus glycoprotein, using fusion proteins synthesized in Escherichia coli by Xu, L, Mourich, D V, Engelking, H M, Ristow, S, Arnzen, J, Leong, J C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections by Iversen, Patrick L, Warren, Travis K, Wells, Jay B, Garza, Nicole L, Mourich, Dan V, Welch, Lisa S, Panchal, Rekha G, Bavari, Sina

“…There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to the development of antisense…”
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Fish vaccine antigens produced or delivered by recombinant DNA technologies by Leong, J C, Anderson, E, Bootland, L M, Chiou, P W, Johnson, M, Kim, C, Mourich, D, Trobridge, G

“…Current efforts to develop vaccines, particularly for aquacultured species, have turned largely to biotechnology because it provides the means to inexpensively…”
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Bacterially expressed nucleoprotein of infectious hematopoietic necrosis virus augments protective immunity induced by the glycoprotein vaccine in fish by Oberg, L.A. (Oregon State University, Corvallis, OR), Wirkkula, J, Mourich, D, Leong, J.C

“…The ribonucleoprotein gene of infectious hematopoietic necrosis virus (IHNV) has been expressed in Escherichia coli as a trpE fusion protein. This viral…”
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Differential Effects of Human Immunodeficiency Virus Isolates on β-Chemokine and Gamma Interferon Production and on Cell Proliferation by Greco, G, Fujimura, S H, Mourich, D V, Levy, J A

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Genetic immunization of rainbow trout (Oncorhynchus mykiss) against infectious hematopoietic necrosis virus by Anderson, E D, Mourich, D V, Fahrenkrug, S C, LaPatra, S, Shepherd, J, Leong, J A

“…Plasmid vectors encoding the infectious hematopoietic necrosis virus (IHNV) nucleoprotein or glycoprotein gene under the control of a cytomegalovirus promoter…”
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The production and characterization of murine monoclonal antibodies to a DNA receptor on human leukocytes by Bennet, RM, Hefeneider, SH, Bakke, A, Merritt, M, Smith, CA, Mourich, D, Heinrich, MC

“…Two murine mAb have been generated with a reactivity toward a 30,000 m.w. DNA binding protein found on the cell surface of human leukocytes; mAb 12A has an…”
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Idiotypic mimicry of a cell surface DNA receptor: evidence for anti‐DNA antibodies being a subset of anti‐anti‐DNA receptor antibodies by BENNETT, R. M., CORNELL, K. A., MERRITT, M. J., BAKKE, A. C., MOURICH, D., HEFENEIDER, S. H.

“…SUMMARY Anti‐idiotypic anti‐DNA antibodies (anti‐anti‐DNA) have previously been described in both patients with systemic lupus erythematosus and healthy…”
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Gene expression in rainbow trout (Oncorhynchus mykiss) following intramuscular injection of DNA by Anderson, E D, Mourich, D V, Leong, J A

“…Expression of the firefly luciferase gene under the control of viral or fish promoters was observed in fish tissue after direct DNA injection of plasmid DNA…”
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Natural killer cell enhancement factor-like gene in rainbow trout (Oncorhynchus mykiss) by Mourich, D V, Hansen, J, Leong, J

“…Fish immunomodulating factors that appear closely related to their mammalian counterparts have been described for a variety of species. However, there have…”
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Ligand Independent Form of CTLA-4 Induced by Antisense Exon Skipping Alters T?Cell Activity and Inhibits Autoimmune Diabetes in Nod Mice by Mourich, D, Johnson, M, Oda, S, Manly, B

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ANTISENSE INHIBITION OF CFLIP PROMOTES TRANSPLANT ACCEPTANCE BY SENSITIZING RESPONDING T CELLS TO UNDERGO ACTIVATION INDUCED CELL DEATH (AICD) by Mourich, D V., Marshall, N, Iversen, P, Hinrichs, D

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