Search Results - "Mouraret, Nathalie"
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Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension
Published in American journal of respiratory cell and molecular biology (01-05-2013)“…Pulmonary artery (PA) smooth muscle cell (SMC) proliferation in pulmonary hypertension (PH) may be linked to dysregulated mammalian target of rapamycin (mTOR)…”
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Activation of Lung p53 by Nutlin-3a Prevents and Reverses Experimental Pulmonary Hypertension
Published in Circulation (New York, N.Y.) (23-04-2013)“…Induction of cellular senescence through activation of the p53 tumor suppressor protein is a new option for treating proliferative disorders. Nutlins prevent…”
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CCR5 as a Treatment Target in Pulmonary Arterial Hypertension
Published in Circulation (New York, N.Y.) (09-09-2014)“…BACKGROUND—Pulmonary arterial hypertension (PH), whether idiopathic or related to underlying diseases such as HIV infection, results from complex vessel…”
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p21-Dependent Protective Effects of a Carbon Monoxide–Releasing Molecule-3 in Pulmonary Hypertension
Published in Arteriosclerosis, thrombosis, and vascular biology (01-02-2014)“…OBJECTIVE—Carbon monoxide–releasing molecules (CORMs) represent a pharmacological alternative to CO gas inhalation. Here, we questioned whether CORM-3, a…”
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Role for telomerase in pulmonary hypertension
Published in Circulation (New York, N.Y.) (24-02-2015)“…Cells exhibiting dysregulated growth may express telomerase reverse transcriptase (TERT), the dual function of which consists of maintaining telomere length,…”
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Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice
Published in American journal of physiology. Lung cellular and molecular physiology (15-09-2012)“…Decreasing the bioavailability of serotonin (5-HT) by inhibiting its biosynthesis may represent a useful adjunctive treatment of pulmonary hypertension (PH)…”
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Rapamycin reverses pulmonary artery smooth muscle cell proliferation in pulmonary hypertension: mTOR Inhibition in Pulmonary Hypertension
Published in American journal of respiratory cell and molecular biology (01-05-2013)“…Pulmonary artery (PA) smooth muscle cell (SMC) proliferation in pulmonary hypertension (PH) may be linked to dysregulated mammalian target of rapamycin (mTOR)…”
Get full text
Journal Article