Search Results - "Moura, Tatiana R de"

Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil by Magalhães, Lucas S, Bomfim, Lays Gs, Mota, Sthefanne G, Cruz, Geydson S, Corrêa, Cristiane B, Tanajura, Diego M, Lipscomb, Michael W, Borges, Valéria M, Jesus, Amélia R de, Almeida, Roque P de, Moura, Tatiana R de

“…BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance…”
Get full text

Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection by de Moura, Tatiana R, Oliveira, Fabiano, Carneiro, Marcia W, Miranda, José Carlos, Clarêncio, Jorge, Barral-Netto, Manoel, Brodskyn, Cláudia, Barral, Aldina, Ribeiro, José M C, Valenzuela, Jesus G, de Oliveira, Camila I

“…Leishmania parasites are transmitted in the presence of sand fly saliva. Together with the parasite, the sand fly injects salivary components that change the…”
Get full text

Immunity to Lutzomyia intermedia saliva modulates the inflammatory environment induced by Leishmania braziliensis by de Moura, Tatiana R, Oliveira, Fabiano, Rodrigues, Gabriele C, Carneiro, Marcia W, Fukutani, Kiyoshi F, Novais, Fernanda O, Miranda, José Carlos, Barral-Netto, Manoel, Brodskyn, Claudia, Barral, Aldina, de Oliveira, Camila I

“…During blood feeding, sand flies inject Leishmania parasites in the presence of saliva. The types and functions of cells present at the first host-parasite…”
Get full text

Dual-task training is as effective as functional training on the functional fitness of older women: a randomized clinical trial by Aragão-Santos, José C, Behm, David G, de Moura, Tatiana R, Da Silva-Grigoletto, Marzo Edir

“…The interest in approaches that improve older individuals' functional fitness and autonomy is increasing. However, the effects of dual-task training on older…”
Get full text

Space-time risk cluster of visceral leishmaniasis in Brazilian endemic region with high social vulnerability: An ecological time series study by Ribeiro, Caique J N, Dos Santos, Allan D, Lima, Shirley V M A, da Silva, Eliete R, Ribeiro, Bianca V S, Duque, Andrezza M, Peixoto, Marcus V S, Dos Santos, Priscila L, de Oliveira, Iris M, Lipscomb, Michael W, de Araújo, Karina C G M, de Moura, Tatiana R

“…Despite visceral leishmaniasis (VL) being epidemic in most Brazilian regions, the Northeast region is responsible for the highest morbidity and mortality…”
Get full text

Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes by Elizondo, Diana M., Brandy, Nailah Z. D., da Silva, Ricardo L. L., de Moura, Tatiana R., Ali, Jamel, Yang, Dazhi, Lipscomb, Michael W.

“…Therapeutic approaches to combat type 1 diabetes (T1D) include donor pancreas transplantation, exogenous insulin administration and immunosuppressive…”
Get full text

The Severity of Visceral Leishmaniasis Correlates with Elevated Levels of Serum IL-6, IL-27 and sCD14 by Dos Santos, Priscila L, de Oliveira, Fabrícia A, Santos, Micheli Luize B, Cunha, Luana Celina S, Lino, Michelle T B, de Oliveira, Michelle F S, Bomfim, Manuela O M, Silva, Angela Maria, de Moura, Tatiana R, de Jesus, Amélia R, Duthie, Malcolm S, Reed, Steven G, de Almeida, Roque P

“…Visceral leishmaniasis (VL) is a severe disease caused by infection with protozoa of the genus Leishmania. Classic VL is characterized by a systemic infection…”
Get full text

Allograft Inflammatory Factor-1 Governs Hematopoietic Stem Cell Differentiation Into cDC1 and Monocyte-Derived Dendritic Cells Through IRF8 and RelB in vitro by Elizondo, Diana M, Brandy, Nailah Z D, da Silva, Ricardo L L, Haddock, Naomi L, Kacsinta, Apollo D, de Moura, Tatiana R, Lipscomb, Michael W

“…The multistep differentiation process from hematopoietic stem cells through common myeloid progenitors into committed dendritic cell (DC) subsets remains to be…”
Get full text

Leishmania infantum Induces the Release of sTREM-1 in Visceral Leishmaniasis by Bomfim, Lays G S, Magalhães, Lucas S, Santos-Filho, Marcello A A, Peres, Nalu T A, Corrêa, Cristiane B, Tanajura, Diego M, Silva, Angela M, Lipscomb, Michael W, Borges, Valéria M, Jesus, Amélia R, Almeida, Roque P, de Moura, Tatiana R

“…Visceral leishmaniasis (VL) is a systemic transmissible disease that remains to be a major global health problem. The inflammatory response during VL is…”
Get full text

Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-alpha production by Souza, Anselmo S, Giudice, Angela, Pereira, Júlia Mb, Guimarães, Luís H, de Jesus, Amelia R, de Moura, Tatiana R, Wilson, Mary E, Carvalho, Edgar M, Almeida, Roque P

“…Nitric oxide (NO) produced in macrophages plays a pivotal role as a leishmanicidal agent. A previous study has demonstrated that 20% of the L. (V.)…”
Get full text

Enhanced Leishmania braziliensis infection following pre-exposure to sandfly saliva by de Moura, Tatiana R, Oliveira, Fabiano, Novais, Fernanda O, Miranda, José Carlos, Clarêncio, Jorge, Follador, Ivonise, Carvalho, Edgar M, Valenzuela, Jesus G, Barral-Netto, Manoel, Barral, Aldina, Brodskyn, Cláudia, de Oliveira, Camila I

“…Sand fly saliva has an array of pharmacological and immunomodulatory components, and immunity to saliva protects against Leishmania infection. In the present…”
Get full text

Toward a Novel Experimental Model of Infection To Study American Cutaneous Leishmaniasis Caused by Leishmania braziliensis by de Moura, Tatiana R, Novais, Fernanda O, Oliveira, Fabiano, Clarêncio, Jorge, Noronha, Almério, Barral, Aldina, Brodskyn, Claudia, de Oliveira, Camila I

“…Leishmania spp. cause a broad spectrum of diseases collectively known as leishmaniasis. Leishmania braziliensis is the main etiological agent of American…”
Get full text

PLGA nanoparticles loaded with KMP-11 stimulate innate immunity and induce the killing of Leishmania by Santos, Diego M, Carneiro, Marcia W, de Moura, Tatiana R, Soto, Manuel, Luz, Nívea F, Prates, Deboraci B, Irache, Juan Manuel, Brodskyn, Claudia, Barral, Aldina, Barral-Netto, Manoel, Espuelas, Socorro, Borges, Valéria M, de Oliveira, Camila I

“…Abstract We recently demonstrated that immunization with polyester poly(lactide-co-glycolide acid) (PLGA) nanoparticles loaded with the 11-kDa Leishmania…”
Get full text

Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages by de Moura, Tatiana R., Santos, Micheli Luize Barbosa, Braz, Juciene M., Santos, Luis Felipe V. C., Aragão, Matheus T., de Oliveira, Fabricia A., Santos, Priscila L., da Silva, Ângela Maria, de Jesus, Amélia Ribeiro, de Almeida, Roque P.

“…Visceral leishmaniasis is a life-threatening disease characterized by intense parasitism of the spleen, liver, and bone marrow. Antimonials have served as…”
Get full text

Allograft inflammatory factor-1 in myeloid cells drives autoimmunity in type 1 diabetes by Elizondo, Diana M, Brandy, Nailah Zd, da Silva, Ricardo L, de Moura, Tatiana R, Lipscomb, Michael W

“…Allograft inflammatory factor-1 (AIF1) is a calcium-responsive cytoplasmic scaffold protein that directs hematopoiesis and immune responses within dendritic…”
Get full text

The presence of Tregs does not preclude immunity to reinfection with Leishmania braziliensis by C. Falcão, Sarah, de Moura, Tatiana R., Clarêncio, Jorge, Brodskyn, Cláudia, Barral, Aldina, de Oliveira, Camila I.

“…[Display omitted] ► Evaluation of the presence of regulatory T cells (Treg) during Leishmania braziliensis infection. ► CD4+CD25+Foxp3+/CD103+/GITR+ T cells…”
Get full text

Towards development of novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded with kinetoplastid membrane protein-11 by Santos, Diego M, Carneiro, Marcia W, de Moura, Tatiana R, Fukutani, Kiyoshi, Clarencio, Jorge, Soto, Manuel, Espuelas, Socorro, Brodskyn, Claudia, Barral, Aldina, Barral-Netto, Manoel, de Oliveira, Camila I

“…Vaccine development has been a priority in the fight against leishmaniases, which are vector-borne diseases caused by Leishmania protozoa. Among the different…”
Get full text

Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil by Magalhães, Lucas S, Bomfim, Lays GS, Mota, Sthefanne G, Cruz, Geydson S, Corrêa, Cristiane B, Tanajura, Diego M, Lipscomb, Michael W, Borges, Valéria M, Jesus, Amélia R de, Almeida, Roque P de, Moura, Tatiana R de

“…BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance…”
Get full text

Resistance of Leishmania braziliensis to nitric oxide: correlation with antimony therapy and TNF-[alpha] production by Souza, Anselmo S, Giudice, Angela, Pereira, Júlia MB, Guimarães, Luís H, de Jesus, Amelia R, de Moura, Tatiana R, Wilson, Mary E, Carvalho, Edgar M, Almeida, Roque P

“…Background Nitric oxide (NO) produced in macrophages plays a pivotal role as a leishmanicidal agent. A previous study has demonstrated that 20% of the L. (V.)…”
Get full text

Resistance of Leishmania by Souza, Anselmo S, Giudice, Angela, Pereira, Júlia MB, Guimarães, Luís H, de Jesus, Amelia R, de Moura, Tatiana R, Wilson, Mary E, Carvalho, Edgar M, Almeida, Roque P

“…Nitric oxide (NO) produced in macrophages plays a pivotal role as a leishmanicidal agent. A previous study has demonstrated that 20% of the L. (V.)…”
Get full text