Search Results - "Moura, Tales Rocha"

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    The cap-binding site of influenza virus protein PB2 as a drug target by Severin, Chelsea, Rocha de Moura, Tales, Liu, Yong, Li, Keqin, Zheng, Xiaofeng, Luo, Ming

    “…The RNA polymerase of influenza virus consists of three subunits: PA, PB1 and PB2. It uses a unique `cap‐snatching' mechanism for the transcription of viral…”
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    Journal Article
  2. 2

    Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes by de Moura, Tales Rocha, Purta, Elżbieta, Bernat, Agata, Martín-Cuevas, Eva M, Kurkowska, Małgorzata, Baulin, Eugene F, Mukherjee, Sunandan, Nowak, Jakub, Biela, Artur P, Rawski, Michał, Glatt, Sebastian, Moreno-Herrero, Fernando, Bujnicki, Janusz M

    Published in Nucleic acids research (12-04-2024)
    “…Betacoronaviruses are a genus within the Coronaviridae family of RNA viruses. They are capable of infecting vertebrates and causing epidemics as well as global…”
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    Journal Article
  3. 3

    Cryo-EM Structure of raiA ncRNA From Clostridium Reveals a New RNA 3D Fold by Badepally, Nagendar Goud, de Moura, Tales Rocha, Purta, Elżbieta, Baulin, Eugene F., Bujnicki, Janusz M.

    Published in Journal of molecular biology (01-12-2024)
    “…[Display omitted] •Cryo-EM reveals the 3D structure of raiA ncRNA from Clostridium sp. CAG 138.•raiA ncRNA adopts a unique globular architecture with a novel…”
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    Journal Article
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    Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors by de Moura, Tales Rocha, Mozaffari-Jovin, Sina, Szabó, Csaba Zoltán Kibédi, Schmitzová, Jana, Dybkov, Olexandr, Cretu, Constantin, Kachala, Michael, Svergun, Dmitri, Urlaub, Henning, Lührmann, Reinhard, Pena, Vladimir

    Published in Molecular cell (15-03-2018)
    “…Human nineteen complex (NTC) acts as a multimeric E3 ubiquitin ligase in DNA repair and splicing. The transfer of ubiquitin is mediated by Prp19—a…”
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    Journal Article
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    A Novel CD34-Specific T-Cell Engager Efficiently Depletes Stem Cells and Acute Myeloid Leukemia Cells in Vitro and In Vivo by Arruda, Lucas C M, Jin, Liqing, Lambert, Melanie, Sanchez Rivera, Laura, Alvez, Renato, Rocha de Moura, Tales, Mim, Carsten, Axelsson-Robertson, Rebecca, Dick, John E., Mattsson, Jonas, Onfelt, Bjorn, Carlsten, Mattias, Uhlin, Michael

    Published in BLOOD (2021)
    “…ASH Abstract. Intro Acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS) are poor prognosis hematological malignancies characterized by…”
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    Journal Article Conference Proceeding
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