Search Results - "Moura, Bruna C."
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Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579
Published in European journal of medicinal chemistry (01-08-2013)“…In an attempt to increase the affinity of our antipsychotic lead compound LASSBio-579 (1-((1-(4-chlorophenyl)-1H-pyrazol-4-yl)methyl)-4-phenylpiperazine; (2))…”
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Salivary MMPs, TIMPs, and MPO levels in periodontal disease patients and controls
Published in Clinica chimica acta (05-06-2013)“…Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases with an important role in physiological and pathological remodeling. Their…”
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Functional binding assays for estimation of the intrinsic efficacy of ligands at the 5-HT1A receptor: Application for screening drug candidates
Published in Journal of pharmacological and toxicological methods (01-07-2014)“…Determination of the intrinsic efficacy of ligands at the 5-HT1A receptor is important for selecting drug candidates, e.g. in the case of schizophrenia where…”
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Functional binding assays for estimation of the intrinsic efficacy of ligands at the 5-HT sub(1A) receptor: Application for screening drug candidates
Published in Journal of pharmacological and toxicological methods (01-08-2014)“…Introduction: Determination of the intrinsic efficacy of ligands at the 5-HT sub(1A) receptor is important for selecting drug candidates, e.g. in the case of…”
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