Search Results - "Mounier, Ninon"

Simultaneous estimation of bi-directional causal effects and heritable confounding from GWAS summary statistics by Darrous, Liza, Mounier, Ninon, Kutalik, Zoltán

“…Mendelian Randomisation (MR) is an increasingly popular approach that estimates the causal effect of risk factors on complex human traits. While it has seen…”
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Structural variant calling: the long and the short of it by Mahmoud, Medhat, Gobet, Nastassia, Cruz-Dávalos, Diana Ivette, Mounier, Ninon, Dessimoz, Christophe, Sedlazeck, Fritz J

“…Recent research into structural variants (SVs) has established their importance to medicine and molecular biology, elucidating their role in various diseases,…”
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Quantification of the overall contribution of gene-environment interaction for obesity-related traits by Sulc, Jonathan, Mounier, Ninon, Günther, Felix, Winkler, Thomas, Wood, Andrew R., Frayling, Timothy M., Heid, Iris M., Robinson, Matthew R., Kutalik, Zoltán

“…The growing sample size of genome-wide association studies has facilitated the discovery of gene-environment interactions (GxE). Here we propose a maximum…”
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Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape by Sulc, Jonathan, Sonrel, Anthony, Mounier, Ninon, Auwerx, Chiara, Marouli, Eirini, Darrous, Liza, Draganski, Bogdan, Kilpeläinen, Tuomas O., Joshi, Peter, Loos, Ruth J. F., Kutalik, Zoltán

“…Obesity is a major risk factor for a wide range of cardiometabolic diseases, however the impact of specific aspects of body morphology remains poorly…”
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Genome-wide Association Studies of Retinal Vessel Tortuosity Identify Numerous Novel Loci Revealing Genes and Pathways Associated With Ocular and Cardiometabolic Diseases by Tomasoni, Mattia, Beyeler, Michael Johannes, Vela, Sofia Ortin, Mounier, Ninon, Porcu, Eleonora, Corre, Tanguy, Krefl, Daniel, Button, Alexander Luke, Abouzeid, Hana, Lazaros, Konstantinidis, Bochud, Murielle, Schlingemann, Reinier, Bergin, Ciara, Bergmann, Sven

“…To identify novel susceptibility loci for retinal vascular tortuosity, to better understand the molecular mechanisms modulating this trait, and reveal causal…”
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Bias correction for inverse variance weighting Mendelian randomization by Mounier, Ninon, Kutalik, Zoltán

“…Inverse‐variance weighted two‐sample Mendelian randomization (IVW‐MR) is the most widely used approach that utilizes genome‐wide association studies (GWAS)…”
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bGWAS: an R package to perform Bayesian genome wide association studies by Mounier, Ninon, Kutalik, Zoltán

“…Abstract Summary Increasing sample size is not the only strategy to improve discovery in Genome Wide Association Studies (GWASs) and we propose here an…”
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Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor by Liang, Xiaoran, Mounier, Ninon, Apfel, Nicolas, Khalid, Sara, Frayling, Timothy M, Bowden, Jack

“…Mendelian randomization (MR) is an epidemiological approach that utilizes genetic variants as instrumental variables to estimate the causal effect of an…”
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Causal Inference Methods to Integrate Omics and Complex Traits by Porcu, Eleonora, Sjaarda, Jennifer, Lepik, Kaido, Carmeli, Cristian, Darrous, Liza, Sulc, Jonathan, Mounier, Ninon, Kutalik, Zoltán

“…Major biotechnological advances have facilitated a tremendous boost to the collection of (gen-/transcript-/prote-/methyl-/metabol-)omics data in very large…”
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Using genetic variation to disentangle the complex relationship between food intake and health outcomes by Pirastu, Nicola, McDonnell, Ciara, Grzeszkowiak, Eryk J, Mounier, Ninon, Imamura, Fumiaki, Merino, Jordi, Day, Felix R, Zheng, Jie, Taba, Nele, Concas, Maria Pina, Repetto, Linda, Kentistou, Katherine A, Robino, Antonietta, Esko, Tõnu, Joshi, Peter K, Fischer, Krista, Ong, Ken K, Gaunt, Tom R, Kutalik, Zoltán, Perry, John R B, Wilson, James F

“…Diet is considered as one of the most important modifiable factors influencing human health, but efforts to identify foods or dietary patterns associated with…”
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Using genetic variation to disentangle the complex relationship between food intake and health outcomes by Nicola Pirastu, Ciara McDonnell, Eryk J. Grzeszkowiak, Ninon Mounier, Fumiaki Imamura, Jordi Merino, Felix R. Day, Jie Zheng, Nele Taba, Maria Pina Concas, Linda Repetto, Katherine A. Kentistou, Antonietta Robino, Tõnu Esko, Peter K. Joshi, Krista Fischer, Ken K. Ong, Tom R. Gaunt, Zoltán Kutalik, John R. B. Perry, James F. Wilson

“…Diet is considered as one of the most important modifiable factors influencing human health, but efforts to identify foods or dietary patterns associated with…”
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