Search Results - "Mounier, Marwa M."

Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2 by El-Sayed, Wael A, Alminderej, Fahad M, Mounier, Marwa M, Nossier, Eman S, Saleh, Sayed M, Kassem, Asmaa F

“…This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar…”
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Phytochemical Profiling and Compound Isolation of Cissus rhombifolia Vahl. Leaves Aqueous Methanolic Extract with the Evaluation of Its Anti‐Inflammatory Effect Using Lipopolysaccharide‐Induced Inflammation in RAW 264.7 Cells by Raslan, Mona A., Mounier, Marwa M.

“…The inflammatory disorders represent a serious health issue. Certain Cissus species possess anti‐inflammatory effect. Cissus rhombifolia Vahl. leaves’…”
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Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide-Glycyrrhetinic-Acid-Based Derivatives by Moustafa, Gaber O, Shalaby, Ahmed, Naglah, Ahmed M, Mounier, Marwa M, El-Sayed, Heba, Anwar, Manal M, Nossier, Eman S

“…Glycyrrhetinic acid (GA) is one of many interesting pentacyclic triterpenoids showing significant anticancer activity by triggering apoptosis in tumor cell…”
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New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation by El-Sayed, Wael A, Alminderej, Fahad M, Mounier, Marwa M, Nossier, Eman S, Saleh, Sayed M, F. Kassem, Asmaa

“…Toxicity and resistance to newly synthesized anticancer drugs represent a challenging phenomenon of intensified concern arising from variation in drug targets…”
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Toward Rational Design of Novel Anti-Cancer Drugs Based on Targeting, Solubility, and Bioavailability Exemplified by 1,3,4-Thiadiazole Derivatives Synthesized Under Solvent-Free Conditions by Rashdan, Huda R M, Farag, Mohammad M, El-Gendey, Marwa S, Mounier, Marwa M

“…The 1,3,4-thiadiazole derivatives ( - ) were synthesized under solvent free conditions and their chemical composition was confirmed using different spectral…”
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Characterization, modeling, and anticancer activity of L.arginase production from marine Bacillus licheniformis OF2 by Selim, Manal S, Mounier, Marwa M, Abdelhamid, Sayeda A, Hamed, Ahmed Abdelghani, Abo Elsoud, Mostafa M, Mohamed, Sahar S

“…L-arginase, is a powerful anticancer that hydrolyzes L-arginine to L-ornithine and urea. This enzyme is widely distributed and expressed in organisms like…”
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Targeting apoptotic anticancer response with natural glucosinolates from cell suspension culture of Lepidium sativum by Ibrahim, Mona M, Mounier, Marwa M, Bekheet, Shawky A

“…Background Finding natural products with anticancer activity is an effective strategy to fight this disease. In this respect, Lepidium sativum or garden cress…”
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Target-based anticancer glycyrrhetinic derivatives: Design, synthesis, biological assessment and molecular docking studies by Moustafa, Gaber O, Kalmouch, Atef, El-Karim, Somaia S. Abd, Nossier, Eman S, Mounier, Marwa M, El-Sayed, Heba, Almehizia, Abdulrahman A, Naglah, Ahmed M, Zen, Amer A

“…18-Glycyrrhetinic acid (GA) is regarded as the principal active component isolated from the Chinese medicinal plant of licorice root, and it has considerable…”
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Production and characterisation of exopolysaccharide from Streptomyces carpaticus isolated from marine sediments in Egypt and its effect on breast and colon cell lines by Selim, Manal S., Amer, Shaimaa K., Mohamed, Sahar S., Mounier, Marwa M., Rifaat, Hala M.

“…Twenty streptomycete strains were isolated from marine sediment samples collected from Nabq area, Sharm El-Sheikh, Red Sea Coast, Egypt. Four of them produce…”
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In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide by Kassem, Asmaa F., Moustafa, Gaber O., Nossier, Eman S., Khalaf, Hemat S., Mounier, Marwa M., Al-Yousef, Suliman A., Mahmoud, Sabry Y.

“…A series of N 1 ,N 3 -bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4-16 were prepared and their structures were confirmed by different spectral…”
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Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells by Batran, Rasha Z., Kassem, Asmaa F., Abbas, Eman M.H., Elseginy, Samia A., Mounier, Marwa M.

“…[Display omitted] •A new set of 4-phenylcoumarins was designed and synthesized.•Cytotoxic effects against MCF-7 were assessed.•Compounds 3a, 3b and 3f were…”
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Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors by Ali, Islam H., Abdel-Mohsen, Heba T., Mounier, Marwa M., Abo-elfadl, Mahmoud T., El Kerdawy, Ahmed M., Ghannam, Iman A.Y.

“…[Display omitted] •Series of 2-arylbenzimidazole derivatives 12a,b, 13a-d and 14a-l were synthesized.•Compounds 14c and 14g-i were the most potent anticancer…”
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Cell based and In vivo systematic evaluation of some Egyptian plant extracts targeting breast cancer by Mahmoud, Khaled, Ahmed A.F, Soliman, Marwa M, Mounier, Zeinab A, Elshahid, Salwa M, El-Hallouty, Walid, Fayad, May A, El-Manawaty, Youssef, Elham M.

“…The prevalence of breast cancer as a significant public health concern necessitates continued exploration of natural resources for novel anti-cancer agents is…”
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Discovery of novel diaryl urea-oxindole hybrids as BRAF kinase inhibitors targeting BRAF and KRAS mutant cancers by Ghannam, Iman A.Y., El Kerdawy, Ahmed M., Mounier, Marwa M., Abo-elfadl, Mahmoud T., Abdel-Mohsen, Heba T.

“…[Display omitted] •A novel series of diaryl urea-oxindole hybrids was rationally designed as BRAF inhibitors.•The synthesized candidates 9a-t exhibit potent…”
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Synthesis of novel heterocyclic compounds bearing tetralin moiety of potential anticancer activity targeting the intrinsic apoptotic pathway by Hamdy, Nehal A., El Sayed, Mardia T., Hussein, Hoda A. R., Mounier, Marwa M., Anwar, Manal M.

“…This study deals with the readily reaction of the enaminone derivative 3 with different reagents to give the corresponding pyrazolo[3,4-b]pyridine,…”
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In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N 1 , N 3 -bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide by Kassem, Asmaa F, Moustafa, Gaber O, Nossier, Eman S, Khalaf, Hemat S, Mounier, Marwa M, Al-Yousef, Suliman A, Mahmoud, Sabry Y

“…A series of -based derivatives - were prepared and their structures were confirmed by different spectral tools. The cytotoxic potentiality of novel compounds -…”
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Novel 2‐oxo‐2‐phenylethoxy and benzyloxy diaryl urea hybrids as VEGFR‐2 inhibitors: Design, synthesis, and anticancer evaluation by Ghannam, Iman A. Y., El Kerdawy, Ahmed M., Mounier, Marwa M., Abo‐elfadl, Mahmoud T., Ali, Islam H.

“…Two series of diaryl urea derivatives, 6a–k and 7a–n, were synthesized. All the newly synthesized compounds were tested against the NCI (US) cancer cell lines…”
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Synthesis of Novel Pyrazole Derivatives as Antineoplastic Agent by Rizk, Sameh A., El‐Sayed, Amira A., Mounier, Marwa M.

“…Anticancer evaluation of pyrazole 2 and Schiff base 5 is reported. Synthesis of some important heterocyclic compounds via 2,3‐diaryloxirane‐2,3‐dicarbonitrile…”
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N α -1, 3-Benzenedicarbonyl-Bis-(Amino Acid) and Dipeptide Candidates: Synthesis, Cytotoxic, Antimicrobial and Molecular Docking Investigation by Naglah, Ahmed M, Moustafa, Gaber O, Elhenawy, Ahmed A, Mounier, Marwa M, El-Sayed, Heba, Al-Omar, Mohamed A, Almehizia, Abdulrahman A, Bhat, Mashooq A

“…The objective of our work was to prepare a potent and safe antimicrobial and anticancer agents, through synthesis of several peptides and examine their…”
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Mycosynthesis of silver nanoparticles using Aspergillus caespitosus: Characterization, antimicrobial activities, cytotoxicity, and their performance as an antimicrobial agent for textile materials by El‐Bendary, Magda A., Moharam, Maysa E., Hamed, Shimaa R., Abo El‐Ola, Samiha M., Khalil, Safaa K. H., Mounier, Marwa M., Roshdy, Amira M., Allam, Mousa A.

“…Mycosynthesis of stable silver nanoparticles (AgNPs) using Aspergillus caespitosus exo‐ and endo‐filtrates were obtained. Both exo‐ and endo‐AgNPs showed an…”
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