Search Results - "Mouncey, Nigel J."
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1
RIViT-seq enables systematic identification of regulons of transcriptional machineries
Published in Nature communications (17-06-2022)“…Transcriptional regulation is a critical process to ensure expression of genes necessary for growth and survival in diverse environments. Transcription is…”
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2
Comparative and pangenomic analysis of the genus Streptomyces
Published in Scientific reports (07-11-2022)“…Streptomycetes are highly metabolically gifted bacteria with the abilities to produce bioproducts that have profound economic and societal importance. These…”
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3
New keys to unlock the treasure trove of microbial natural products
Published in Nature reviews. Microbiology (01-11-2021)“…This month’s Genome Watch highlights how recent advances in computational identification of biosynthetic gene clusters (BGCs), and in their experimental…”
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4
The National Microbiome Data Collaborative: enabling microbiome science
Published in Nature reviews. Microbiology (01-06-2020)“…To harness the potential of microbiome science across the broad range of relevant disciplines, new approaches to data infrastructure and transdisciplinary…”
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5
Tiny Earth: A Big Idea for STEM Education and Antibiotic Discovery
Published in mBio (16-02-2021)“…The world faces two seemingly unrelated challenges-a shortfall in the STEM workforce and increasing antibiotic resistance among bacterial pathogens. We address…”
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Metabolic Engineering of Gluconobacter oxydans for Improved Growth Rate and Growth Yield on Glucose by Elimination of Gluconate Formation
Published in Applied and Environmental Microbiology (01-07-2010)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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7
Coassembly and binning of a twenty-year metagenomic time-series from Lake Mendota
Published in Scientific data (04-09-2024)“…The North Temperate Lakes Long-Term Ecological Research (NTL-LTER) program has been extensively used to improve understanding of how aquatic ecosystems respond…”
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8
Phylogenomics and genetic analysis of solvent-producing Clostridium species
Published in Scientific data (01-05-2024)“…The genus Clostridium is a large and diverse group within the Bacillota (formerly Firmicutes), whose members can encode useful complex traits such as solvent…”
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9
IMG-ABC v.5.0: an update to the IMG/Atlas of Biosynthetic Gene Clusters Knowledgebase
Published in Nucleic acids research (08-01-2020)“…Abstract Microbial secondary metabolism is a reservoir of bioactive compounds of immense biotechnological and biomedical potential. The biosynthetic machinery…”
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10
The secondary metabolism collaboratory: a database and web discussion portal for secondary metabolite biosynthetic gene clusters
Published in Nucleic acids research (14-11-2024)“…Abstract Secondary metabolites are small molecules produced by all corners of life, often with specialized bioactive functions with clinical and environmental…”
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11
Compendium of Metabolomic and Genomic Datasets for Cyanobacteria: Mined the Gap
Published in Water research (Oxford) (01-06-2024)“…Cyanobacterial blooms, producing toxic secondary metabolites, are becoming increasingly common phenomena in the face of rising global temperatures. They are…”
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12
Cytochromes P450 involved in bacterial RiPP biosyntheses
Published in Journal of industrial microbiology & biotechnology (17-02-2023)“…Abstract Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a large class of secondary metabolites that have garnered scientific…”
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13
A centimeter-long bacterium with DNA contained in metabolically active, membrane-bound organelles
Published in Science (American Association for the Advancement of Science) (24-06-2022)“…Cells of most bacterial species are around 2 micrometers in length, with some of the largest specimens reaching 750 micrometers. Using fluorescence, x-ray, and…”
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14
New voyages to explore the natural product galaxy
Published in Journal of industrial microbiology & biotechnology (01-03-2019)“…Natural products are a large family of diverse and complex chemical molecules that have roles in both primary and secondary metabolism, and over 210,000…”
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15
Development of platforms for functional characterization and production of phenazines using a multi-chassis approach via CRAGE
Published in Metabolic engineering (01-01-2022)“…Phenazines (Phzs), a family of chemicals with a phenazine backbone, are secondary metabolites with diverse properties such as antibacterial, anti-fungal, or…”
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16
CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria
Published in Nature microbiology (01-12-2019)“…It is generally believed that exchange of secondary metabolite biosynthetic gene clusters (BGCs) among closely related bacteria is an important driver of BGC…”
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17
An integrated workflow for phenazine-modifying enzyme characterization
Published in Journal of industrial microbiology & biotechnology (01-07-2018)“…Increasing availability of new genomes and putative biosynthetic gene clusters (BGCs) has extended the opportunity to access novel chemical diversity for…”
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18
Expanding the genomic encyclopedia of Actinobacteria with 824 isolate reference genomes
Published in Cell genomics (14-12-2022)“…The phylum Actinobacteria includes important human pathogens like Mycobacterium tuberculosis and Corynebacterium diphtheriae and renowned producers of…”
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The emergence of microbiome centres
Published in Nature microbiology (01-01-2020)“…As microbiome science expands, academic centres scramble to fill many needs, from service provider to industry liaison. A newly created network aims to share…”
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20
Cascade Regulation of Dimethyl Sulfoxide Reductase (dor) Gene Expression in the Facultative Phototroph Rhodobacter sphaeroides 2.4.1T
Published in Journal of Bacteriology (01-06-1998)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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