Search Results - "Moule, Madeleine G"

Mycobacterium tuberculosis Dissemination Plays a Critical Role in Pathogenesis by Moule, Madeleine G, Cirillo, Jeffrey D

“…is primarily a respiratory pathogen. However, 15% of infections worldwide occur at extrapulmonary sites causing additional complications for diagnosis and…”
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Reciprocal analysis of Francisella novicida infections of a Drosophila melanogaster model reveal host-pathogen conflicts mediated by reactive oxygen and imd-regulated innate immune response by Moule, Madeleine G, Monack, Denise M, Schneider, David S

“…The survival of a bacterial pathogen within a host depends upon its ability to outmaneuver the host immune response. Thus, mutant pathogens provide a useful…”
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Bacillus Calmette-Guérin vaccination as defense against SARS-CoV-2 (BADAS): a randomized controlled trial to protect healthcare workers in the USA by enhanced trained immune responses by DiNardo, Andrew R, Arditi, Moshe, Kamat, Ashish M, Koster, Kent J, Carrero, Santiago, Nishiguchi, Tomoki, Lebedev, Maxim, Benjamin, Aaron B, Avalos, Pablo, Lozano, Marisa, Moule, Madeleine G, McCune, Brittany, Herron, Baysia, Ladki, Malik, Sheikh, Daanish, Spears, Matthew, Herrejon, Ivan A, Dodge, Courtney, Kumar, Sathish, Hutchison, Robert W, Ofili, Theresa U, Opperman, Lynne A, Bernard, Jessica A, Lerner, Seth P, Udeani, George, Neal, Gabriel, Netea, Mihai G, Cirillo, Jeffrey D

“…A large epidemic, such as that observed with SARS-CoV-2, seriously challenges available hospital capacity, and this would be augmented by infection of…”
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Genome-wide saturation mutagenesis of Burkholderia pseudomallei K96243 predicts essential genes and novel targets for antimicrobial development by Moule, Madeleine G, Hemsley, Claudia M, Seet, Qihui, Guerra-Assunção, José Afonso, Lim, Jiali, Sarkar-Tyson, Mitali, Clark, Taane G, Tan, Patrick B O, Titball, Richard W, Cuccui, Jon, Wren, Brendan W

“…Burkholderia pseudomallei is the causative agent of melioidosis, an often fatal infectious disease for which there is no vaccine. B. pseudomallei is listed as…”
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Efficacy of Cathelicidin-Mimetic Antimicrobial Peptoids against Staphylococcus aureus by Benjamin, Aaron B, Moule, Madeleine G, Didwania, Maruti K, Hardy, Jonathan, Saenkham-Huntsinger, Panatda, Sule, Preeti, Nielsen, Josefine Eilsø, Lin, Jennifer S, Contag, Christopher H, Barron, Annelise E, Cirillo, Jeffrey D

“…Staphylococcus aureus is one of the most common pathogens associated with infection in wounds. The current standard of care uses a combination of disinfection…”
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An O-Antigen Glycoconjugate Vaccine Produced Using Protein Glycan Coupling Technology Is Protective in an Inhalational Rat Model of Tularemia by Wren, Brendan W., Prior, Joann L., Atkins, Timothy P., Denman, Carmen, Moule, Madeleine G., Jenner, Dominic C., Whelan, Adam O., Davies, Carwyn H., Nelson, M., Marshall, Laura E., Cuccui, Jon

“…There is a requirement for an efficacious vaccine to protect people against infection from Francisella tularensis, the etiological agent of tularemia. The…”
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Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection by Moule, Madeleine G., Benjamin, Aaron B., Burger, Melanie L., Herlan, Claudine, Lebedev, Maxim, Lin, Jennifer S., Koster, Kent J., Wavare, Neha, Adams, Leslie G., Bräse, Stefan, Munoz-Medina, Ricardo, Cannon, Carolyn L., Barron, Annelise E., Cirillo, Jeffrey D.

“…The rise of drug resistance has become a global crisis, with >1 million deaths due to resistant bacterial infections each year. Pseudomonas aeruginosa , in…”
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Author Correction: Peptide-mimetic treatment of Pseudomonas aeruginosa in a mouse model of respiratory infection by Moule, Madeleine G., Benjamin, Aaron B., Burger, Melanie L., Herlan, Claudine, Lebedev, Maxim, Lin, Jennifer S., Koster, Kent J., Wavare, Neha, Adams, Leslie G., Bräse, Stefan, Munoz-Medina, Ricardo, Cannon, Carolyn L., Barron, Annelise E., Cirillo, Jeffrey D.

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Exploitation of bacterial N-linked glycosylation to develop a novel recombinant glycoconjugate vaccine against Francisella tularensis by Cuccui, Jon, Thomas, Rebecca M., Moule, Madeleine G., D'Elia, Riccardo V., Laws, Thomas R., Mills, Dominic C., Williamson, Diane, Atkins, Timothy P., Prior, Joann L., Wren, Brendan W.

“…Glycoconjugate-based vaccines have proved to be effective at producing long-lasting protection against numerous pathogens. Here, we describe the application of…”
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Twin Arginine Translocation System Is Essential for Aerobic Growth and Full Virulence of Burkholderia thailandensis by Wagley, Sariqa, Hemsley, Claudia, Thomas, Rachael, Moule, Madeleine G, Vanaporn, Muthita, Andreae, Clio, Robinson, Matthew, Goldman, Stan, Wren, Brendan W, Butler, Clive S, Titball, Richard W

“…The twin arginine translocation (Tat) system in bacteria is responsible for transporting folded proteins across the cytoplasmic membrane, and in some bacteria,…”
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Drosophila eiger mutants are sensitive to extracellular pathogens by Schneider, David S, Ayres, Janelle S, Brandt, Stephanie M, Costa, Alexandre, Dionne, Marc S, Gordon, Michael D, Mabery, Eric M, Moule, Madeleine G, Pham, Linh N, Shirasu-Hiza, Mimi M

“…We showed previously that eiger, the Drosophila tumor necrosis factor homolog, contributes to the pathology induced by infection with Salmonella typhimurium…”
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Role for PP2A in ARF Signaling to p53 by Moule, Madeleine G., Collins, Crista H., McCormick, Frank, Fried, Mike, Cleaver, James E.

“…Activation of the ARF-p53 tumor suppressor pathway is one of the cell's major defense mechanisms against cancer induced by oncogenes. The ARF-p53 pathway is…”
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Safety and delivery efficiency of a photodynamic treatment of the lungs using indocyanine green and extracorporeal near infrared illumination by Kassab, Giulia, Cheburkanov, Vsevolod, Willis, Jace, Moule, Madeleine G., Kurachi, Cristina, Yakovlev, Vladislav, Cirillo, Jeffrey D., Bagnato, Vanderlei S.

“…Photodynamic inactivation (PDI) is a promising alternative for combating infections caused by antimicrobial resistant bacteria. Pneumonias are among the most…”
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Characterization of New Virulence Factors Involved in the Intracellular Growth and Survival of Burkholderia pseudomallei by Moule, Madeleine G, Spink, Natasha, Willcocks, Sam, Lim, Jiali, Guerra-Assunção, José Afonso, Cia, Felipe, Champion, Olivia L, Senior, Nicola J, Atkins, Helen S, Clark, Taane, Bancroft, Gregory J, Cuccui, Jon, Wren, Brendan W

“…Burkholderia pseudomallei, the causative agent of melioidosis, has complex and poorly understood extracellular and intracellular lifestyles. We used…”
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Polyelectrolyte Complex that Minimizes Bacterial Adhesion to Polyester by Smith, Ryan J., Moule, Madeleine G., Leon, Pablo A., Iverson, Ethan T., Kolibaba, Thomas J., Cirillo, Jeffrey D., Grunlan, Jaime C.

“…Bacterial adhesion is a major concern in the medical field, where bacterial fouling can lead to diminished device efficacy and failure. To combat this,…”
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The Rat ARF Protein is Translated from Two Closely Spaced ATG Start Codons and Can Transcriptionally Activate p53 in the Absence of p53 Protein Stabilization by Hunt, Abigail E., Moule, Madeleine G., Fried, Mike

“…We have analyzed the transcriptional start sites of the rat ARF gene and theamino acid sequence of the rat ARF tumor suppressor protein. The 5' end of the…”
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Polyelectrolyte Multilayer Nanocoating Dramatically Reduces Bacterial Adhesion to Polyester Fabric by Smith, Ryan J, Moule, Madeleine G, Sule, Preeti, Smith, Travis, Cirillo, Jeffrey D, Grunlan, Jaime C

“…Bacterial adhesion to textiles is thought to contribute to odor and infection. Alternately exposing polyester fabric to aqueous solutions of…”
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Reciprocal Analysis of Francisella novicida Infections of a Drosophila melanogaster Model Reveal Host-Pathogen Conflicts Mediated by Reactive Oxygen and imd-Regulated Innate Immune Response: e1001065 by Moule, Madeleine G, Monack, Denise M, Schneider, David S

“…The survival of a bacterial pathogen within a host depends upon its ability to outmaneuver the host immune response. Thus, mutant pathogens provide a useful…”
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Reciprocal analysis of Francisella novicida infections of a Drosophilae melanogaster model reveal host-pathogen conflicts mediated by reactive oxygen and imd-regulated innate immune response by Moule, Madeleine G, Monack, Denise M, Schneider, David S

“…The survival of a bacterial pathogen within a host depends upon its ability to outmaneuver the host immune response. Thus, mutant pathogens provide a useful…”
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Drosophila eiger mutants are sensitive to extracellular pathogens by Schneider, David S, Ayres, Janelle S, Brandt, Stephanie M, Costa, Alexandre, Dionne, Marc S, Gordon, Michael D, Mabery, Eric M, Moule, Madeleine G, Pham, Linh N, Shirasu-Hiza, Mimi M

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