Search Results - "Moulds, Courtney"

Antisense Gene Inhibition by Oligonucleotides Containing C-5 Propyne Pyrimidines by Wagner, Richard W., Matteucci, Mark D., Lewis, Jason G., Gutierrez, Arnold J., Moulds, Courtney, Froehler, Brian C.

“…Phosphorothioate oligodeoxynucleotides containing the C-5 propyne analogs of uridine and cytidine bind RNA with high affinity and are potent antisense…”
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Site and Mechanism of Antisense Inhibition by C-5 Propyne Oligonucleotides by Moulds, Courtney, Lewis, Jason G, Froehler, Brian C, Grant, Deborah, Huang, Teresa, Milligan, John F, Matteucci, Mark D, Wagner, Richard W

“…Antisense gene inhibition occurs when an oligonucleotide (ON) has sufficient binding affinity such that it hybridizes its reverse complementary target RNA and…”
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Multiple Biological Activities are Expressed by a Mouse Interleukin 6 cDNA Clone Isolated from Bone Marrow Stromal Cells by Chiu, Choy-Pik, Moulds, Courtney, Coffman, Robert L., Rennick, Donna, Lee, Frank

“…Interleukin 6 (IL-6) refers to the gene product that was characterized initially as β 2 interferon/26-kDa protein produced by human fibroblasts and later was…”
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Oligonucleotide-Mediated Triple Helix Formation Using an N3-Protonated Deoxycytidine Analog Exhibiting pH-Independent Binding Within the Physiological Range by Krawczyk, Steven H., Milligan, John F., Wadwani, Shalini, Moulds, Courtney, Froehler, Brian C., Matteucci, Mark D.

“…Triple helix formation with pyrimidine deoxyoligonucleotides for the sequence-specific recognition of DNA duplex targets suffers from a decrease in affinity as…”
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Clonal rearrangements of T-cell receptor genes in mycosis fungoides and dermatopathic lymphadenopathy by Weiss, L M, Hu, E, Wood, G S, Moulds, C, Cleary, M L, Warnke, R, Sklar, J

“…Histologic diagnosis of mycosis fungoides may be difficult, especially in lymph nodes that show changes frequently associated with chronic skin disease. As an…”
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Deoxyoligonucleotides bearing neutral analogs of phosphodiester linkages recognize duplex DNA via triple-helix formation by Matteucci, Mark, Lin, Kuei Ying, Butcher, Samuel, Moulds, Courtney

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Interleukin-6. A multifunctional regulator of growth and differentiation by Lee, F, Chiu, C P, Wideman, J, Hodgkin, P, Hudak, S, Troutt, L, Ng, T, Moulds, C, Coffman, R, Zlotnik, A

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