Search Results - "Mouhamad, Shahul"

Apoptosis regulation in tetraploid cancer cells by Castedo, Maria, Coquelle, Arnaud, Vivet, Sonia, Vitale, Ilio, Kauffmann, Audrey, Dessen, Philippe, Pequignot, Marie O, Casares, Noelia, Valent, Alexandre, Mouhamad, Shahul, Schmitt, Elise, Modjtahedi, Nazanine, Vainchenker, William, Zitvogel, Laurence, Lazar, Vladimir, Garrido, Carmen, Kroemer, Guido

“…Tetraploidy can result in cancer‐associated aneuploidy. As shown here, freshly generated tetraploid cells arising due to mitotic slippage or failed cytokinesis…”
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Two Overlapping Domains of a Lyssavirus Matrix Protein That Acts on Different Cell Death Pathways by LARROUS, Florence, GHOLAMI, Alireza, MOUHAMAD, Shahul, ESTAQUIER, Jérôme, BOURHY, Hervé

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Apaf-1 Deficiency Causes Chromosomal Instability by Mouhamad, Shahul, Galluzzi, Lorenzo, Zermati, Yael, Castedo, Maria, Kroemer, Guido

“…Apaf-1 is an essential component of the apoptosome, the molecular complex assembled in response to mitochondrial cytochrome c release that promotes caspase…”
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IL-2 immunotherapy in chronically SIV-infected Rhesus macaques by Garibal, Julie, Laforge, Mireille, Silvestre, Ricardo, Mouhamad, Shahul, Campillo-Gimenez, Laure, Lévy, Yves, Estaquier, Jérôme

“…Despite inducing a sustained increase in CD4+ T cell counts, intermittent recombinant IL-2 (rIL-2) therapy did not confer a better clinical outcome in…”
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EBV Infection of Human B Lymphocytes Leads to Down-Regulation of Bim Expression: Relationship to Resistance to Apoptosis by Clybouw, Cyril, Mchichi, Bouchra, Mouhamad, Shahul, Auffredou, Marie Therese, Bourgeade, Marie Francoise, Sharma, Surendra, Leca, Gerald, Vazquez, Aime

“…EBV infects a large proportion of the human population worldwide and is one of the major viruses with human B lymphocyte tropism. It can immortalize human B…”
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Cdk2 associates with MAP Kinase in vivo and its nuclear translocation is dependent on MAP Kinase activation in IL-2-dependent Kit 225 T lymphocytes by BLANCHARD, D. A, MOUHAMAD, S, AUFFREDOU, M.-T, PESTY, A, BERTOGLIO, J, LECA, G, VAZQUEZ, A

“…Cell proliferation is controlled by cdk2 which in association with cyclin E and A regulates G1/S transition and S phase progression. cdk2 activation is…”
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The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques by Laforge, Mireille, Silvestre, Ricardo, Rodrigues, Vasco, Garibal, Julie, Campillo-Gimenez, Laure, Mouhamad, Shahul, Monceaux, Valérie, Cumont, Marie-Christine, Rabezanahary, Henintsoa, Pruvost, Alain, Cordeiro-da-Silva, Anabela, Hurtrel, Bruno, Silvestri, Guido, Senik, Anna, Estaquier, Jérôme

“…Apoptosis has been proposed as a key mechanism responsible for CD4+ T cell depletion and immune dysfunction during HIV infection. We demonstrated that…”
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Notch activation on effector T cells increases their sensitivity to Treg cell‐mediated suppression through upregulation of TGF‐βRII expression by Hue, Sophie, Kared, Hassen, Mehwish, Younas, Mouhamad, Shahul, Balbo, Michelle, Levy, Yves

“…Notch proteins play an important role in embryonic development and cell‐fate decisions. Notch influences also the activation and differentiation of peripheral…”
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Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint by Zermati, Yael, Mouhamad, Shahul, Stergiou, Lilli, Besse, Benjamin, Galluzzi, Lorenzo, Boehrer, Simone, Pauleau, Anne-Laure, Rosselli, Filippo, D'Amelio, Marcello, Amendola, Roberto, Castedo, Maria, Hengartner, Michael, Soria, Jean-Charles, Cecconi, Francesco, Kroemer, Guido

“…Apaf-1 is an essential factor for cytochrome c-driven caspase activation during mitochondrial apoptosis but has also an apoptosis-unrelated function. Knockdown…”
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Selective Resistance of Tetraploid Cancer Cells against DNA Damage-Induced Apoptosis by CASTEDO, MARIA, COQUELLE, ARNAUD, VITALE, ILIO, VIVET, SONIA, MOUHAMAD, SHAHUL, VIAUD, SOPHIE, ZITVOGEL, LAURENCE, KROEMER, GUIDO

“…:  Aneuploidy and chromosomal instability, which are frequent in cancer, can result from the asymmetric division of tetraploid precursors. Genomic instability…”
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Notch activation on effector T cells increases their sensitivity to Treg cell-mediated suppression through upregulation of TGF-[beta]RII expression by Hue, Sophie, Kared, Hassen, Mehwish, Younas, Mouhamad, Shahul, Balbo, Michelle, Levy, Yves

“…Notch proteins play an important role in embryonic development and cell-fate decisions. Notch influences also the activation and differentiation of peripheral…”
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Notch activation on effector T cells increases their sensitivity to T reg cell‐mediated suppression through upregulation of TGF ‐β RII expression by Hue, Sophie, Kared, Hassen, Mehwish, Younas, Mouhamad, Shahul, Balbo, Michelle, Levy, Yves

“…Notch proteins play an important role in embryonic development and cell‐fate decisions. Notch influences also the activation and differentiation of peripheral…”
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Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint by Zermati, Yael, Mouhamad, Shahul, Stergiou, Lilli, Besse, Benjamin, Galluzzi, Lorenzo, Boehrer, Simone, Pauleau, Anne-Laure, Rosselli, Filippo, D’Amelio, Marcello, Amendola, Roberto, Castedo, Maria, Hengartner, Michael, Soria, Jean-Charles, Cecconi, Francesco, Kroemer, Guido

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chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint by Mondragón, Laura, Galluzzi, Lorenzo, Mouhamad, Shahul, Orzáez, Mar, Vicencio, José-Miguel, Vitale, Ilio, Moure, Alejandra, Messeguer, Angel, Perez-Paya, Enrique, Kroemer, Guido

“…QM31 represents a new class of cytoprotective agents that inhibit the formation of the apoptosome, the caspase activation complex composed by Apaf-1,…”
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Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism by Renault-Mihara, François, Beuvon, Frédéric, Iturrioz, Xavier, Canton, Brigitte, De Bouard, Sophie, Léonard, Nadine, Mouhamad, Shahul, Sharif, Ariane, Ramos, Joe W, Junier, Marie-Pierre, Chneiweiss, Hervé

“…Phosphoprotein enriched in astrocytes-15 kDa (PEA-15), a phosphoprotein enriched in astrocytes, inhibits both apoptosis and proliferation in normal and…”
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p38-mediated Regulation of an Fas-associated Death Domain Protein-independent Pathway Leading to Caspase-8 Activation during TGFβ-induced Apoptosis in Human Burkitt Lymphoma B Cells BL41 by Schrantz, Nicolas, Bourgeade, Marie-Françoise, Mouhamad, Shahul, Leca, Gérald, Sharma, Surendra, Vazquez, Aimé

“…On binding to its receptor, transforming growth factor β (TGFβ) induces apoptosis in a variety of cells, including human B lymphocytes. We have previously…”
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Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis by Coquelle, Arnaud, Mouhamad, Shahul, Pequignot, Marie O., Braun, Thorsten, Carvalho, Gabrielle, Vivet, Sonia, Métivier, Didier, Castedo, Maria, Kroemer, Guido

“…The susceptibility of cells to apoptosis induction is deeply influenced by their position in the cell cycle. Unfortunately, however, current methods for the…”
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B Cell Receptor-Mediated Apoptosis of Human Lymphocytes Is Associated with a New Regulatory Pathway of Bim Isoform Expression by Mouhamad, Shahul, Besnault, Laurence, Auffredou, Marie Therese, Leprince, Corinne, Bourgeade, Marie Francoise, Leca, Gerald, Vazquez, Aime

“…Studies in Bim-deficient mice have shown that the proapoptotic molecule Bim plays a key role in the control of B cell homeostasis and activation. However, the…”
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Differential modulation of interleukin-2-and interleukin-4-mediated early activation of normal human B lymphocytes by the caspase inhibitor zVAD-fmk by Mouhamad, Shahul, Arnoult, Damien, Auffredou, Marie-Thérèse, Estaquier, Jérome, Vazquez, Aimé

“…Caspases are a group of cysteine-related proteases that control the process of apoptosis and may also be involved in the control of lymphocyte activation. We…”
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Cdk2 associates with MAP Kinase in vivoand its nuclear translocation is dependent on MAP Kinase activation in IL-2-dependent Kit 225 T lymphocytes by Blanchard, Dominique Alain, Mouhamad, Shahul, Auffredou, Marie-Therese, Pesty, Arlette, Bertoglio, Jacques, Leca, Gerald, Vazquez, Aime

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