Search Results - "Mouchiroud, G."

Src-family kinases play an essential role in differentiation signaling downstream of macrophage colony-stimulating factor receptors mediating persistent phosphorylation of phospholipase C- gamma 2 and MAP kinases ERK1 and ERK2 by Bourgin-Hierle, C, Gobert-Gosse, S, Therier, J, Grasset, M-F, Mouchiroud, G

“…Macrophage colony-stimulating factor (M-CSF) has been found to be involved in multiple developmental processes, especially production of cells belonging to the…”
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Src-family kinases play an essential role in differentiation signaling downstream of macrophage colony-stimulating factor receptors mediating persistent phosphorylation of phospholipase C-γ2 and MAP kinases ERK1 and ERK2 by Bourgin-Hierle, C, Gobert-Gosse, S, Thérier, J, Grasset, M-F, Mouchiroud, G

“…Macrophage colony-stimulating factor (M-CSF) has been found to be involved in multiple developmental processes, especially production of cells belonging to the…”
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E2a Pbx1 oncogene inhibits terminal differentiation but not myeloid potential of pro-T cells by BOURETTE, R. P, GRASSET, M.-F, MOUCHIROUD, G

“…E2a/Pbx1 is a fusion oncoprotein resulting from the t(1;19) translocation found in human pre-B acute lymphocytic leukemia and in a small number of acute…”
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Characterization of promoter elements directing Mona/Gads molecular adapter expression in T and myelomonocytic cells: involvement of the AML-1 transcription factor by Guyot, B., Mouchiroud, G.

“…Monocytic adaptor (Mona, also called Gads) is a molecular adaptor implicated in T cell activation and macrophage differentiation. The objective of this study…”
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Src-family kinases play an essential role in differentiation signaling downstream of macrophage colony-stimulating factor receptors mediating persistent phosphorylation of phospholipase C-gamma2 and MAP kinases ERK1 and ERK2 by Bourgin-Hierle, C, Gobert-Gosse, S, Thérier, J, Grasset, M-F, Mouchiroud, G

“…Macrophage colony-stimulating factor (M-CSF) has been found to be involved in multiple developmental processes, especially production of cells belonging to the…”
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Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development by Bourette, Roland P., Arnaud, Sylvie, Myles, Gary M., Blanchet, Jean-Paul, Rohrschneider, Larry R., Mouchiroud, Guy

“…The production, survival and function of monocytes and macrophages are regulated by the macrophage colony‐stimulating factor (M‐CSF or CSF‐1) through its…”
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Suppressor of Cytokine Signaling 1 Interacts with the Macrophage Colony-stimulating Factor Receptor and Negatively Regulates Its Proliferation Signal by Bourette, Roland P., De Sepulveda, Paulo, Arnaud, Sylvie, Dubreuil, Patrice, Rottapel, Robert, Mouchiroud, Guy

“…Macrophage colony-stimulating factor receptor (M-CSF-R) is a tyrosine kinase that regulates proliferation, differentiation, and cell survival during monocytic…”
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Expression of Mona (monocytic adapter) in myeloid progenitor cells results in increased and prolonged MAP kinase activation upon macrophage colony-stimulating factor stimulation by Bourgin, Caroline, Bourette, Roland, Mouchiroud, Guy, Arnaud, Sylvie

“…Mona is an SH3 and SH2 domain-containing adapter molecule that is induced during monocytic differentiation. Here we have first shown that M-CSFR is the major…”
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Genomic organization and restricted expression of the human Mona/Gads gene suggests regulation by two specific promoters by Guyot, B, Arnaud, S, Phothirath, P, Bourette, R.P, Grasset, M.-F, Rigal, D, Mouchiroud, G

“…Monocytic adaptor (Mona) also known as Gads is a Grb2-related adaptor whose expression is restricted to hematopoietic cells. It plays an important role in…”
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Role of the membrane form of human colony-stimulating factor-1 (CSF-1) in proliferation of multipotent hematopoietic FDCP-Mix cells expressing human CSF-1 receptor by TSUBOI, I, REVOL, V, BLANCHET, J. P, MOUCHIROUD, G

“…Because IL-3-dependent multipotential FDCP-Mix cells expressing human colony-stimulating factor-1 (CSF-1) receptor did not proliferate in response to soluble…”
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Modulation of human and mouse erythropoiesis by thyroid hormone and retinoic acid: evidence for specific effects at different steps of the erythroid pathway by Perrin, M C, Blanchet, J P, Mouchiroud, G

“…Receptors for L-triiodothyronine (T3) and alltrans retinoic acid (ATRA) are DNA-binding proteins that can form transcriptionally active heterodimers. In this…”
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Myogenic progenitor cells exhibit IFN type I-driven pro-angiogenic properties and molecular signature during juvenile dermatomyositis by Gitiaux, C., Latroche, C., Weiss-Gayet, M., Rodero, M., Duffy, D., Bader Meunier, B., Bodemer, C., Mouchiroud, G., Chelly, J., Germain, S., Desguerre, I., Chazaud, B.

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P.197 - Myogenic progenitor cells exhibit IFN type I-driven pro-angiogenic properties and molecular signature during juvenile dermatomyositis by Gitiaux, C., Latroche, C., Weiss-Gayet, M., Rodero, M., Duffy, D., Bader Meunier, B., Bodemer, C., Mouchiroud, G., Chelly, J., Germain, S., Desguerre, I., Chazaud, B.

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Colony-stimulating factor-1 impairs both proliferation and differentiation signals of erythropoietin during the commitment of bipotential NFS-60 cell line to the monocytic lineage by Pawlak, Géraldine, Valadoux-Delplanque, Cathy, Revol, Valérie, Bourette, Roland P, Blanchet, Jean-Paul, Mouchiroud, Guy

“…The interleukin-3 (IL-3) dependent cell line NFS-60 contains bipotential progenitors that exhibit both erythroid and myelomonocytic potentials. In order to…”
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Instructive role of M‐CSF on commitment of bipotent myeloid cells involves ERK‐dependent positive and negative signaling by Carras, Sylvain, Valayer, Alexandre, Moratal, Claudine, Weiss‐Gayet, Michèle, Pages, Gilles, Morlé, Francois, Mouchiroud, Guy, Gobert, Stéphanie

“…The role of PKCδ and ERK during molecular mechanism of myeloid differentiation in bipotent progenitors. M‐CSF and G‐CSF are instructive cytokines that…”
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A novel growth-factor–dependent myeloid cell line derived from mouse bone marrow cells contains progenitors endowed with high proliferative potential by Revol, Valérie, Tsuboi, Isao, Flamant, Frédéric, Samarut, Jacques, Blanchet, Jean-Paul, Mouchiroud, Guy

“…Constitutive expression of human colony-stimulating factor-1 receptor (CSF-1R) confers long-lasting CSF-1–dependent proliferation to mouse myeloid cell lines…”
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Expression of Human Colony-Stimulating Factor-1 (CSF-1) Receptor in Murine Pluripotent Hematopoietic NFS-60 Cells Induces Long-Term Proliferation in Response to CSF-1 Without Loss of Erythroid Differentiation Potential by Bourette, Roland P., Mouchiroud, Guy, Ouazana, Roland, Morlé, François, Godet, Jacqueline, Blanchet, Jean-Paul

“…NFS-60 and FDCP-Mix cells are interleukin-3–dependent multipotent hematopoietic cells that can differentiate in vitro into mature myeloid and erythroid cells…”
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Human chronic myeloid leukemic cell line with positive Philadelphia chromosome exhibits megakaryocytic and erythroid characteristics by Seigneurin, D, Champelovier, P, Mouchiroud, G, Berthier, R, Leroux, D, Prenant, M, McGregor, J, Starck, J, Morle, F, Micouin, C

“…A cell line (LAMA-84) has been established from the blood of a patient with chronic myeloid leukemia in acute phase. LAMA-84 cells retained the patient's…”
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Analyse des capacités de régénération des cellules souches musculaires dans la dermatomyosite by Gallay, L., Hot, A., Streichenberger, N., Mouchiroud, G., Chazaud, B.

“…Dans la dermatomyosite (DM), la balance nécrose/régénération de la fibre musculaire apparaît comme négative, avec une lésion musculaire chronique, dictant…”
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Isolation and characterization of c-fos-expressing murine bone marrow stromal cell lines supporting myeloid differentiation by Steff, A M, Bouaboula, M, Mouchiroud, G, Arnaud, S, Roux, P, Cassellas, P, Piechaczyk, M

“…We have previously reported that constitutive expression of c-fos oncogene allows long-term proliferation of primary mouse bone marrow stromal cells favoring…”
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