Search Results - "Motz, Carina"
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Magic-Angle Spinning Frequencies beyond 300 kHz Are Necessary To Yield Maximum Sensitivity in Selectively Methyl Protonated Protein Samples in Solid-State NMR
Published in Journal of physical chemistry. C (19-07-2018)“…In the last decade, proton detection in magic-angle spinning (MAS) solid-state NMR became a popular strategy for biomolecular structure determination. In…”
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Paramyxovirus V Proteins Disrupt the Fold of the RNA Sensor MDA5 to Inhibit Antiviral Signaling
Published in Science (American Association for the Advancement of Science) (08-02-2013)“…The retinoic acid—inducible gene I (RIG-I)—like receptor (RLR) melanoma differentiation—associated protein 5 (MDA5) senses cytoplasmic viral RNA and activates…”
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Limits of Resolution and Sensitivity of Proton Detected MAS Solid-State NMR Experiments at 111 kHz in Deuterated and Protonated Proteins
Published in Scientific reports (07-08-2017)“…MAS solid-state NMR is capable of determining structures of protonated solid proteins using proton-detected experiments. These experiments are performed at MAS…”
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DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa
Published in Proceedings of the National Academy of Sciences - PNAS (22-12-2009)“…DCP1 stimulates the decapping enzyme DCP2, which removes the mRNA 5' cap structure committing mRNAs to degradation. In multicellular eukaryotes, DCP1-DCP2…”
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MAS dependent sensitivity of different isotopomers in selectively methyl protonated protein samples in solid state NMR
Published in Journal of biomolecular NMR (01-11-2019)Get full text
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Cryo-EM shows how dynactin recruits two dyneins for faster movement
Published in Nature (London) (08-02-2018)“…Dynein and its cofactor dynactin form a highly processive microtubule motor in the presence of an activating adaptor, such as BICD2. Different adaptors link…”
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The structure of the dynactin complex and its interaction with dynein
Published in Science (American Association for the Advancement of Science) (27-03-2015)“…Dynactin is an essential cofactor for the microtubule motor cytoplasmic dynein-1. We report the structure of the 23-subunit dynactin complex by cryo-electron…”
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MAS dependent sensitivity of different isotopomers in selectively methyl protonated protein samples in solid state NMR
Published in Journal of biomolecular NMR (01-11-2019)“…Sensitivity and resolution together determine the quality of NMR spectra in biological solids. For high-resolution structure determination with solid-state…”
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