Search Results - "Mottram, Peter"

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma by Kryczek, Ilona, Zou, Linhua, Rodriguez, Paulo, Zhu, Gefeng, Wei, Shuang, Mottram, Peter, Brumlik, Michael, Cheng, Pui, Curiel, Tyler, Myers, Leann, Lackner, Andrew, Alvarez, Xavier, Ochoa, Augusto, Chen, Lieping, Zou, Weiping

“…Tumor-associated macrophages are a prominent component of ovarian cancer stroma and contribute to tumor progression. B7-H4 is a recently identified B7 family…”
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Modulation of vacuolar pH is required for replication of Edwardsiella ictaluri in channel catfish macrophages by Baumgartner, Wes A, Dubytska, Lidiya, Rogge, Matthew L, Mottram, Peter J, Thune, Ronald L

“…Previous in vitro work demonstrated that Edwardsiella ictaluri produces an acid-activated urease that can modulate environmental pH through the production of…”
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Biodistribution and toxicity of orally administered poly (lactic-co-glycolic) acid nanoparticles to F344 rats for 21 days by Navarro, Sara M, Morgan, Timothy W, Astete, Carlos E, Stout, Rhett W, Coulon, Diana, Mottram, Peter, Sabliov, Cristina M

“…Quantify the biodistribution and assess the toxicity of PLGA (poly-lactic-co-glycolic acid) and surface-modified PLGA chitosan (PLGA/Chi) nanoparticles (NPs)…”
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Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer by CURIEL, Tyler J, PUI CHENG, LACKNER, Andrew, CARMELIET, Peter, WEIPING ZOU, MOTTRAM, Peter, ALVAREZ, Xavier, MOONS, Lieve, EVDEMON-HOGAN, Melina, SHUANG WEI, LINHUA ZOU, KRYCZEK, Ilona, HOYLE, Gary

“…Angiogenesis is essential for both primary and metastatic tumor growth. Tumor blood vessel formation is complex and regulated by many factors. Ovarian…”
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Hepatocyte ploidy in cats with and without hepatocellular carcinoma by Post, Jacqueline, Langohr, Ingeborg M, Webster, Cynthia R L, Mottram, Peter, Liu, Chin-Chi, Johnston, Andrea

“…Domestic cats rarely develop hepatocellular carcinoma. The reason for the low prevalence is unknown. Reductions in hepatocellular ploidy have been associated…”
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Possible role of glial cells in the onset and progression of Lyme neuroborreliosis by Ramesh, Geeta, Borda, Juan T, Gill, Amy, Ribka, Erin P, Morici, Lisa A, Mottram, Peter, Martin, Dale S, Jacobs, Mary B, Didier, Peter J, Philipp, Mario T

“…Lyme neuroborreliosis (LNB) may present as meningitis, cranial neuropathy, acute radiculoneuropathy or, rarely, as encephalomyelitis. We hypothesized that…”
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Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma by Kryczek, Ilona, Wei, Shuang, Zhu, Gefeng, Myers, Leann, Mottram, Peter, Cheng, Pui, Chen, Lieping, Coukos, George, Zou, Weiping

“…B7-H4 is a recently identified B7 family member. We previously showed that ovarian tumor and associated macrophages expressed B7-H4; tumor B7-H4+ macrophages…”
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Hepatocyte Ploidy in Cats with and without Hepatocellular Carcinoma by Post, Jacqueline, Langohr, Ingeborg, Liu, Chin-Chi, Mottram, Peter, Webster, Cynthia R. L., Johnston, Andrea

“…Hepatocellular carcinoma (HCC) is one of the most common causes of cancer related death in humans, yet it is an uncommon neoplasm in the domestic cat. The…”
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CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers by KRYCZEK, Ilona, LANGE, Andrzej, EMILIE, Dominique, TERRASSA, Margarita, LACKNER, Andrew, CURIEL, Tyler J, CARMELIET, Peter, WEIPING ZOU, MOTTRAM, Peter, ALVAREZ, Xavier, PUI CHENG, HOGAN, Melina, MOONS, Lieve, SHUANG WEI, LINHUA ZOU, MACHELON, Véronique

“…Ovarian carcinomas have a poor prognosis, often associated with multifocal i.p. dissemination accompanied by intense neovascularization. To examine tumor…”
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Cutting Edge: Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells by Kryczek, Ilona, Wei, Shuang, Zou, Linhua, Zhu, Gefeng, Mottram, Peter, Xu, Huanbin, Chen, Lieping, Zou, Weiping

“…Multiple modes of suppressive mechanisms including IL-10 are thought to be implicated in CD4+CD25+ regulatory T (Treg) cell-mediated suppression. However, the…”
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Inhalation of particulate matter containing environmentally persistent free radicals induces endothelial dysfunction mediated via AhR activation at the air-blood interface by Aryal, Ankit, Harmon, Ashlyn C, Varner, K J, Noël, Alexandra, Cormier, Stephania A, Nde, Divine B, Mottram, Peter, Maxie, Jemiah, Dugas, Tammy R

“…Abstract Particulate matter (PM) containing environmentally persistent free radicals (EPFR) is formed by the incomplete combustion of organic wastes, resulting…”
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Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival by Zou, Weiping, Curiel, Tyler J, Coukos, George, Zou, Linhua, Alvarez, Xavier, Cheng, Pui, Mottram, Peter, Evdemon-Hogan, Melina, Conejo-Garcia, Jose R, Zhang, Lin, Burow, Matthew, Zhu, Yun, Wei, Shuang, Kryczek, Ilona, Daniel, Ben, Gordon, Alan, Myers, Leann, Lackner, Andrew, Disis, Mary L, Knutson, Keith L, Chen, Lieping

“…Regulatory T (T(reg)) cells mediate homeostatic peripheral tolerance by suppressing autoreactive T cells. Failure of host antitumor immunity may be caused by…”
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Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma by SHUANG WEI, KRYCZEK, Ilona, LINHUA ZOU, DANIEL, Ben, PUI CHENG, MOTTRAM, Peter, CURIEL, Tyler, LANGE, Andrzej, WEIPING ZOU

“…To directly dissect the role of each immune component in human tumor immunopathogenesis, we have studied the interaction between dendritic cells and T cells in…”
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Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signals by Zou, Linhua, Barnett, Brian, Safah, Hana, Larussa, Vincent F, Evdemon-Hogan, Melina, Mottram, Peter, Wei, Shuang, David, Odile, Curiel, Tyler J, Zou, Weiping

“…CD4(+)CD25(+) regulatory T cells (Tregs) mediate peripheral T-cell homeostasis and contribute to self-tolerance. Their homeostatic and pathologic trafficking…”
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Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity by Curiel, Tyler J, Zou, Weiping, Wei, Shuang, Dong, Haidong, Alvarez, Xavier, Cheng, Pui, Mottram, Peter, Krzysiek, Roman, Knutson, Keith L, Daniel, Ben, Zimmermann, Maria Carla, David, Odile, Burow, Matthew, Gordon, Alan, Dhurandhar, Nina, Myers, Leann, Berggren, Ruth, Hemminki, Akseli, Alvarez, Ronald D, Emilie, Dominique, Curiel, David T, Chen, Lieping

“…Suppression of dendritic cell function in cancer patients is thought to contribute to the inhibition of immune responses and disease progression. Molecular…”
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Phenylalanine residues at the carboxyl terminus of the herpes simplex virus 1 UL20 membrane protein regulate cytoplasmic virion envelopment and infectious virus production by Charles, Anu-Susan, Chouljenko, Vladimir N, Jambunathan, Nithya, Subramanian, Ramesh, Mottram, Peter, Kousoulas, Konstantin G

“…The herpes simplex virus type 1 (HSV-1) UL20 gene encodes a 222-amino-acid nonglycosylated envelope protein which forms a complex with viral glycoprotein K…”
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Localization of Upstream Elements Involved in Transcriptional Regulation of the Rat Testis-Specific Histone H1t Gene in Somatic Cells by WOLFE, S. A, MOTTRAM, P. J, VANWERT, J. M, GRIMES, S. R

“…The testis-specific histone H1t is synthesized exclusively in late pachytene primary spermatocytes during spermatogenesis. The mechanisms involved in…”
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Induction of B7-H4 on APCs through IL-10: Novel Suppressive Mode for Regulatory T Cells by Kryczek, Ilona, Wei, Shuang, Zou, Linhua, Zhu, Gefeng, Mottram, Peter, Xu, Huanbin, Chen, Lieping, Zou, Weiping

“…Multiple modes of suppressive mechanisms including IL-10 are thought to be implicated in CD4 super(+)CD25 super(+) regulatory T (Treg) cell-mediated…”
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Relationship between B7-H4T regulatory Τ cells, and patient outcome in human ovarian carcinoma by KRYCZEK, Ilona, SHUANG WEI, GEFENG ZHU, MYERS, Leann, MOTTRAM, Peter, PUI CHENG, LIEPING CHEN, COUKOS, George, WEIPING ZOU

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Plasmacytoid Dendritic Cells Induce CD8 super(+) Regulatory T Cells In Human Ovarian Carcinoma by Wei, Shuang, Kryczek, Ilona, Zou, Linhua, Daniel, Ben, Cheng, Pui, Mottram, Peter, Curiel, Tyler, Lange, Andrzej, Zou, Weiping

“…To directly dissect the role of each immune component in human tumor immunopathogenesis, we have studied the interaction between dendritic cells and T cells in…”
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