Search Results - "Mott, D D"

Mammary gland development: cell fate specification, stem cells and the microenvironment by Inman, Jamie L, Robertson, Claire, Mott, Joni D, Bissell, Mina J

“…The development of the mammary gland is unique: the final stages of development occur postnatally at puberty under the influence of hormonal cues. Furthermore,…”
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Regulation of matrix biology by matrix metalloproteinases by Mott, Joni D, Werb, Zena

“…Matrix metalloproteinases (MMPs) are endopeptidases that contribute to growth, development and wound healing as well as to pathologies such as arthritis and…”
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Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic Plasticity by Grillo, Claudia A, Piroli, Gerardo G, Lawrence, Robert C, Wrighten, Shayna A, Green, Adrienne J, Wilson, Steven P, Sakai, Randall R, Kelly, Sandra J, Wilson, Marlene A, Mott, David D, Reagan, Lawrence P

“…Insulin receptors (IRs) are expressed in discrete neuronal populations in the central nervous system, including the hippocampus. To elucidate the functional…”
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Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1 by Mori, Hidetoshi, Lo, Alvin T, Inman, Jamie L, Alcaraz, Jordi, Ghajar, Cyrus M, Mott, Joni D, Nelson, Celeste M, Chen, Connie S, Zhang, Hui, Bascom, Jamie L, Seiki, Motoharu, Bissell, Mina J

“…Epithelial cell invasion through the extracellular matrix (ECM) is a crucial step in branching morphogenesis. The mechanisms by which the mammary epithelium…”
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Bayesian QTL analyses using pedigreed families of an outcrossing species, with application to fruit firmness in apple by Bink, M. C. A. M, Jansen, J, Madduri, M, Voorrips, R. E, Durel, C.-E, Kouassi, A. B, Laurens, F, Mathis, F, Gessler, C, Gobbin, D, Rezzonico, F, Patocchi, A, Kellerhals, M, Boudichevskaia, A, Dunemann, F, Peil, A, Nowicka, A, Lata, B, Stankiewicz-Kosyl, M, Jeziorek, K, Pitera, E, Soska, A, Tomala, K, Evans, K. M, Fernández-Fernández, F, Guerra, W, Korbin, M, Keller, S, Lewandowski, M, Plocharski, W, Rutkowski, K, Zurawicz, E, Costa, F, Sansavini, S, Tartarini, S, Komjanc, M, Mott, D, Antofie, A, Lateur, M, Rondia, A, Gianfranceschi, L, van de Weg, W. E

“…KEY MESSAGE : Proof of concept of Bayesian integrated QTL analyses across pedigree-related families from breeding programs of an outbreeding species. Results…”
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Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo by Beliveau, Alain, Mott, Joni D, Lo, Alvin, Chen, Emily I, Koller, Antonius A, Yaswen, Paul, Muschler, John, Bissell, Mina J

“…Organization into polarized three-dimensional structures defines whether epithelial cells are normal or malignant. In a model of morphogenesis, we show that…”
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Isoform-Specific Activation of Latent Transforming Growth Factor β (LTGF-β) by Reactive Oxygen Species by Jobling, Michael F., Mott, Joni D., Finnegan, Monica T., Jurukovski, Vladimir, Erickson, Anna C., Walian, Peter J., Taylor, Scott E., Ledbetter, Steven, Lawrence, Catherine M., Rifkin, Daniel B., Barcellos-Hoff, Mary Helen

“…Jobling, M. F., Mott, J. D., Finnegan, M. T., Jurukovski, V., Erickson, A. C., Walian, P. J., Taylor, S. E., Ledbetter, S., Lawrence, C. M., Rifkin, D. B. and…”
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Cervical and systemic concentrations of long acting hormonal contraceptive (LARC) progestins depend on delivery method: Implications for the study of HIV transmission by Buckner, Lyndsey R, Drobnis, Erma Z, Augustine, Molly S, Rogers, Lynette K, Akers, Jill, Mott, Patricia D, Hope, Thomas J, Quayle, Alison J, Schust, Danny J

“…Progestin-only long-acting reversible contraceptives (LARCs) are increasingly popular among women seeking contraception; however, recent epidemiological…”
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IgG4-specific responses in patients with Staphylococcus aureus bone infections are not predictive of postoperative complications by Owen, J R, Campbell, M P, Mott, M D, Beck, C A, Xie, C, Muthukrishnan, G, Daiss, J L, Schwarz, E M, Kates, S L

“…The most prevalent pathogen in bone infections is Staphylococcus aureus; its incidence and severity are partially determined by host factors. Prior studies…”
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New and Better Detectors for the JWST Near-Infrared Spectrograph by Rauscher, Bernard J., Boehm, Nicholas, Cagiano, Steve, Delo, Gregory S., Foltz, Roger, Greenhouse, Matthew A., Hickey, Michael, Hill, Robert J., Kan, Emily, Lindler, Don, Mott, D. Brent, Waczynski, Augustyn, Wen, Yiting

“…ESA and NASA recently selected two 5 μm cutoff Teledyne H2RG sensor chip assemblies (SCA) for flight on the James Webb Space Telescope (JWST) Near Infrared…”
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Polo-like Kinase 1 Is Involved in Invasion through Extracellular Matrix by RIZKI, Aylin, MOTT, Joni D, BISSELL, Mina J

“…Polo-like kinase 1 (PLK1) has important functions in maintaining genome stability via its role in mitosis. Because PLK1 is up-regulated in many invasive…”
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A Conceptual Framework for the Spruce Budworm Early Intervention Strategy: Can Outbreaks be Stopped? by Robert C. Johns, Joseph J. Bowden, Drew R. Carleton, Barry J. Cooke, Sara Edwards, Erik J. S. Emilson, Patrick M. A. James, Dan Kneeshaw, David A. MacLean, Véronique Martel, Eric R. D. Moise, Gordon D. Mott, Chris J. Norfolk, Emily Owens, Deepa S. Pureswaran, Dan T. Quiring, Jacques Régnière, Brigitte Richard, Michael Stastny

“…The spruce budworm, Choristoneura fumiferana, Clem., is the most significant defoliating pest of boreal balsam fir (Abies balsamea (L.) Mill.) and spruce…”
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Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP-14 by Gomes, Angélica Maciel, Bhat, Ramray, Correia, Ana Luísa, Mott, Joni D., Ilan, Neta, Vlodavsky, Israel, Pavão, Mauro S.G., Bissell, Mina

“…ABSTRACT The development of the mammary gland involves formation of a branched arboreal structure resulting from the penetration and proliferation of…”
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Unraveling the role of zinc in memory by Mott, David D, Dingledine, Raymond

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A Human Breast Cell Model of Preinvasive to Invasive Transition by RIZKI, Aylin, WEAVER, Valerie M, SAIRA MIAN, I, BOROWSKY, Alexander D, JENSEN, Roy A, IDOWU, Michael O, FANQING CHEN, CHEN, David J, PETERSEN, Ole W, GRAY, Joe W, BISSELL, Mina J, LEE, Sun-Young, ROZENBERG, Gabriela I, CHIN, Koei, MYERS, Connie A, BASCOM, Jamie L, MOTT, Joni D, SEMEIKS, Jeremy R, GRATE, Leslie R

“…A crucial step in human breast cancer progression is the acquisition of invasiveness. There is a distinct lack of human cell culture models to study the…”
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Subunit-specific desensitization of heteromeric kainate receptors by Mott, David D., Rojas, Asheebo, Fisher, Janet L., Dingledine, Raymond J., Benveniste, Morris

“…Kainate receptor subunits can form functional channels as homomers of GluK1, GluK2 or GluK3, or as heteromeric combinations with each other or incorporating…”
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Functional neuroanatomy of amygdalohippocampal interconnections and their role in learning and memory by McDonald, Alexander J., Mott, David D.

“…The amygdalar nuclear complex and hippocampal/parahippocampal region are key components of the limbic system that play a critical role in emotional learning…”
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Improved Reference Sampling and Subtraction: A Technique for Reducing the Read Noise of Near-infrared Detector Systems by Rauscher, Bernard J., Arendt, Richard G., Fixsen, D. J., Greenhouse, Matthew A., Lander, Matthew, Lindler, Don, Loose, Markus, Moseley, S. H., Mott, D. Brent, Wen, Yiting, Wilson, Donna V., Xenophontos, Christos

“…Near-infrared array detectors, like the James Webb Space Telescope (JWST) NIRSpec’s Teledyne’s H2RGs, often provide reference pixels and a reference output…”
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Phenylethanolamines inhibit NMDA receptors by enhancing proton inhibition by Mott, David D, Doherty, James J, Zhang, Sunan, Washburn, Mark S, Fendley, Morris J, Lyuboslavsky, Polina, Traynelis, Stephen F, Dingledine, Raymond

“…The phenylethanolamines, ifenprodil and CP-101,606, are NMDA receptor antagonists with promising neuroprotective properties. In recombinant NMDA receptors…”
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Neuregulin blocks synaptic strengthening after epileptiform activity in the rat hippocampus by Iyengar, Sloka S, Mott, David D

“…Abstract Synaptic strengthening produced by epileptiform activity may contribute to seizure progression and cognitive impairment in epilepsy. Agents that limit…”
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