Search Results - "Motoki, Takahiro"
-
1
Hypertension and Proteinuria as Predictive Factors of Effects of Bevacizumab on Advanced Breast Cancer in Japan
Published in Biological & pharmaceutical bulletin (2018)“…Bevacizumab (BV), an inhibitor of vascular endothelial growth factor, is used in combination with paclitaxel (PTX) to treat advanced breast cancer…”
Get full text
Journal Article -
2
Disaster Pharmacists' Support and Challenges Faced by Hospital Pharmacy Departments in the Disaster Response for the 2024 Noto Peninsula Earthquake
Published in The Tohoku Journal of Experimental Medicine (2024)“…The 2024 Noto Peninsula Earthquake, which reached a maximum intensity of 7, led to the deterioration of critical services including electricity, water,…”
Get full text
Journal Article -
3
A puerperal patient with agranulocytosis during tazobactam / piperacillin administration : A case report
Published in The Journal of Medical Investigation (2021)“…Tazobactam / piperacillin (TAZ / PIPC) is an injectable combination drug consisting of a broad-spectrum penicillin and a β-lactamase inhibitor. This…”
Get full text
Journal Article -
4
Renal dysfunction can occur in advanced‐stage Duchenne muscular dystrophy
Published in Muscle & nerve (01-02-2020)“…Introduction With improved treatments, patients with Duchenne muscular dystrophy (DMD) can survive far beyond adolescence. However, advanced‐stage DMD patients…”
Get full text
Journal Article -
5
Relationship between Epidermal Growth Factor Receptor Mutations and Adverse Events in Non-Small Cell Lung Cancer Patients treated with Afatinib
Published in The Journal of Medical Investigation (2021)“…Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors such as afatinib are used for non-small cell lung cancer (NSCLC) and show varying efficacy…”
Get full text
Journal Article -
6
Improved developmental quality in a patient with trisomy 21 following treatment for refractory Lennox-Gastaut syndrome by total corpus callosotomy: a case report
Published in Epilepsy & Seizure (2022)“…The indications for surgical intervention for epilepsy associated with chromosomal abnormalities remain controversial. We report a 13-year-old girl with…”
Get full text
Journal Article -
7
Incidence of infantile spinal muscular atrophy on Shikoku Island of Japan
Published in Brain & development (Tokyo. 1979) (01-01-2019)“…Spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by homozygous mutations in the SMN1 gene. SMA has long been known to be the most common…”
Get full text
Journal Article -
8
A Pharmacist's Query Avoiding Exacerbation of Adverse Effects in a Patient with Acyclovir Encephalopathy: A Case Report
Published in Yakugaku zasshi (01-07-2022)Get full text
Journal Article -
9
Developing Population Pharmacokinetic Parameters for High-Dose Methotrexate Therapy: Implication of Correlations among Developed Parameters for Individual Parameter Estimation Using the Bayesian Least-Squares Method
Published in Biological & pharmaceutical bulletin (2014)“…Bayesian estimation enables the individual pharmacokinetic parameters of the medication administrated to be estimated using only a few blood concentrations…”
Get full text
Journal Article -
10
Therapeutic Effect of Linezolid in Children With Health Care–Associated Meningitis or Ventriculitis
Published in Clinical pediatrics (01-12-2018)“…We evaluated the efficacy of linezolid treatment in 6 children with health care–associated meningitis or ventriculitis (HCAMV) caused by gram-positive cocci…”
Get full text
Journal Article -
11
What information can change the attitude of teachers toward the human papillomavirus vaccine?
Published in The journal of obstetrics and gynaecology research (01-04-2018)“…Aim We conducted a self‐administered survey on the perception of teachers toward human papillomavirus (HPV) vaccine to determine the ways to increase their…”
Get full text
Journal Article -
12
Enhancing carbapenem antimicrobial dosing optimization: synergy of antimicrobial stewardship teams and ward-based clinical pharmacists
Published in Antimicrobial stewardship & healthcare epidemiology : ASHE (2024)“…Antimicrobial-product package inserts and insufficient staffing impede routine carbapenem monitoring in the inpatient setting in Japan. The collaboration…”
Get full text
Journal Article -
13
Survey of patients with spinal muscular atrophy on the island of Shikoku, Japan
Published in Brain & development (Tokyo. 1979) (01-09-2020)“…Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder associated with spinal motor neuron loss and characterized by generalized muscle weakness…”
Get full text
Journal Article -
14
Treatable renal failure found in non-ambulatory Duchenne muscular dystrophy patients
Published in Neuromuscular disorders : NMD (01-10-2015)“…Highlights • We describe Duchenne muscular dystrophy (DMD) patients with treatable renal failure. • CystatinC is a useful marker of kidney function in reduced…”
Get full text
Journal Article -
15
Changes in the Incidence of Infantile Spinal Muscular Atrophy in Shikoku, Japan between 2011 and 2020
Published in International journal of neonatal screening (26-09-2022)“…Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disorder. Al-though there was no cure for SMA, newly developed therapeutic drugs…”
Get full text
Journal Article -
16
Episodic tremors representing cortical myoclonus are characteristic in Angelman syndrome due to UBE3A mutations
Published in Brain & development (Tokyo. 1979) (01-02-2015)“…Abstract Objective Neurological manifestations including psychomotor developmental delay and epilepsy in patients with Angelman syndrome caused by ubiquitin…”
Get full text
Journal Article -
17
A Pharmacist's Query Avoiding Exacerbation of Adverse Effects in a Patient with Acyclovir Encephalopathy: A Case Report
Published in YAKUGAKU ZASSHI (01-07-2022)“…We report a haemodialysis patient with end-stage renal failure whom a pharmacist aided in the management of acyclovir (ACV) encephalopathy, which may have been…”
Get full text
Journal Article -
18
Positron emission tomography with glucose hypermetabolism of a hypothalamic hamartoma in infantile spasms associated with Pallister–Hall syndrome
Published in Brain & development (Tokyo. 1979) (01-09-2010)“…Abstract Although hypothalamic hamartomas (HHs) have been shown to be intrinsically epileptogenic and to participate in the generation of gelastic seizures, no…”
Get full text
Journal Article -
19
Inhibition of Hepatocyte Growth Factor Induction in Human Dermal Fibroblasts by Tryptanthrin
Published in Biological & Pharmaceutical Bulletin (01-02-2005)“…In addition to regulation of normal cell functions, hepatocyte growth factor (HGF) has also been shown to be involved in malignant cell transformation and in…”
Get full text
Journal Article -
20
Inhibition of tumor–stromal interaction through HGF/Met signaling by valproic acid
Published in Biochemical and biophysical research communications (01-02-2008)“…Hepatocyte growth factor (HGF), which is produced by surrounding stromal cells, including fibroblasts and endothelial cells, has been shown to be a significant…”
Get full text
Journal Article